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6581
Low-Cost Electronic Microfluidics for Multiplexed Point-of-Care Biomarker Detection
Published 2024“…It was validated by measuring spiked IL-6 concentrations in human blood, with applications demonstrated in CAR-T patient monitoring and small molecule detection for drug regulation. …”
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Thesis -
6582
Towards a Single Bio-molecule Detector Based on CMOS Nanofluidic Platform
Published 2024“…Cytokines secretion is a core component of the function of many cell therapy products: It affects the tissue repair capacity of induced Pluripotent Stem Cells (iPSCs) and Mesenchymal Stem cells (MSCs) and the tumorigenicity of Chimeric Antigen Receptor (CAR) T-cell therapies. Ideally, we would be able to continuously monitor the secretome of these cell therapies as they are transformed and expanded in manufacturing.However, state-of-theart techniques for monitoring typically low concentrations of cytokines require either Mass Spectroscopy (MS) or immunoassays like Enzyme-linked Immunosorbent Assay (ELISA). …”
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Thesis -
6583
Biologically inspired visual intelligence for unmanned ground vehicles
Published 2012“…Based on empirical evidences, it is known that when human drivers become familiar with the road situations, they prefer to look at the far field where the road edges converge (called the vanishing point) to anticipate the upcoming road trajectory and the car steering with maximal lead time. Based on these findings, vanishing point is considered as a salient and consistent feature during most of the open driving behavior tasks regardless of type of the environments. …”
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Thesis -
6584
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6585
Carbon–cement supercapacitors as a scalable bulk energy storage solution
Published 2024“…Texture analysis reveals that the hydration reactions of cement in the presence of carbon generate a fractal-like electron-conducting carbon network that permeates the load-bearing cement-based matrix. The energy storage capacity of this space-filling carbon black network of the high specific surface area accessible to charge storage is shown to be an intensive quantity, whereas the high-rate capability of the carbon-cement electrodes exhibits self-similarity due to the hydration porosity available for charge transport. …”
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Article -
6586
Dual Origin of Viscoelasticity in Polymer-Carbon Black Hydrogels: A Rheometry and Electrical Spectroscopy Study
Published 2024“…Here we focus on aqueous dispersions of hydrophobic colloidal soot particles, namely carbon black (CB) dispersed with a sodium salt of carboxymethylcellulose (CMC), a food additive known as cellulose gum that bears hydrophobic groups, which are liable to bind physically to CB particles. …”
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Article -
6587
SARS-CoV-2 evolution during treatment of chronic infection
Published 2021“…In vitro, the spike double mutant bearing both ΔH69/ΔV70 and D796H conferred modestly decreased sensitivity to convalescent plasma, while maintaining infectivity levels that were similar to the wild-type virus.The spike substitution mutant D796H appeared to be the main contributor to the decreased susceptibility to neutralizing antibodies, but this mutation resulted in an infectivity defect. …”
Journal article -
6588
Molecular pathways leading to sleep and wakefulness in Drosophila
Published 2021“…In the chronically sleep-deprived flies bearing a mutation for the crossveinless-c (cv-c) gene, the dFB neurons were previously found in electrical quiescence as well. …”
Thesis -
6589
Melatonin and health: an umbrella review of health outcomes and biological mechanisms of action
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Journal Article -
6590
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6591
BOR2G: Building Optimal Regularised Reconstructions with GPUs (in cubes)
Published 2017“…We evaluate the quantitative performance of our proposed method through the use of synthetic and real-world datasets—including datasets from Stanford's Burghers of Calais, University of Oxford's RobotCar, University of Oxford’s Dense Reconstruction, and Karlsruhe Institute of Technology’s KITTI—compared to ground-truth laser data. …”
Thesis -
6592
Mathematical foundation of data science
Published 2020“…High-dimensional probability theory bears vital importance in the mathematical foundation of data science. …”
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Final Year Project (FYP) -
6593
Organic solvent-assisted control of hydrogel structures and properties
Published 2024“…However, major limitations still exist for hydrogels, especially their mechanical weakness, which limits their use in load-bearing applications. In addition, due to their soft and wet nature, it remains technically challenging to generate hydrogel structures with complex geometries as the well-established techniques developed for shaping traditional engineering materials, such as machining and lithography, are no longer useful. …”
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Thesis-Doctor of Philosophy -
6594
An investigation on correlation between linguistic features and personality traits : a case of Singapore Twitter users.
Published 2013“…Furthermore, the usage of vulgarities bearing inversed correlations with first-person pronouns in the plural forms also augmented the hypothesis since the usage of vulgarities in a collectivistic society is undesirable. …”
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Thesis -
6595
Polymeric nanoparticles and organic fluorophores for cancer sensing and therapy
Published 2016“…We have extended this work to the in-vivo system and the nano formulation showed a positive effect on the tumor bearing nude mice. Apart from tackling the disease by developing an efficient system for therapeutic purposes, diagnostic strategies developments are also a key aspect that the biomedical societies are focusing on. …”
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Thesis -
6596
Alkaline earth complexes supported by chelating diamido ligands
Published 2024“…</p> <p>A THF-free synthetic route enabled the isolation and characterisation of a new family of dimeric calcium, strontium and barium complexes bearing phenyl-substituted 1,8-bis(silylamido)naphthalene ligands, which display two distinct dimerisation modes and form unstable monomeric adducts when dissolved in THF.…”
Thesis -
6597
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6598
Cognitive Effects of Simulated Galactic Cosmic Radiation Are Mediated by ApoE Status, Sex, and Environment in APP Knock-In Mice
Published 2024“…Here, we investigated the central nervous system (CNS) effects of 0 Gy (sham) or 0.75 Gy five-ion GCRsim or 2 Gy gamma radiation (IRR) in 14-month-old female and male APP<sup>NL-F/NL-F</sup> knock-in (KI) mice bearing humanized ApoE3 or ApoE4 (APP;E3F and APP;E4F). …”
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Article -
6599
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6600