Nanosized silica particles for achiral drug separation by Tan, Timothy Thatt Yang.

“…It is widely recognized that the full potential of rapid chromatography can be realized with very small support particulates and tailor-made chiral stationary phase. …”
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Collection and analysis on data from Drugs.com by Aw, Teng Teng

“…In this report, Scrapy, is a web scraper, which will be used to extract data from Drugs.com. Scrapy is a framework, done in Python and the outputs will be saved in JSON files. …”
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18F-labelling of new chemotypes for drug discovery by Khotavivattana, T

“…Finally, Chapter 5 gives full experimental procedures and characterisation data for all compounds.…”

Amplifying signals in the tumor microenvironment for drug development and diagnostics by Martin Alonso, Maria Carmen

“…Leveraging advancements in high throughput screening and in deep learning, we contribute important tools for the effective design of conditional drugs that require the cleavage of a protease substrate to unleash drug cytotoxicity. …”
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Controlled-release nanoencapsulating microcapsules to combat inflammatory diseases by Baek, Jong-Suep, Yeo, Eng Wan, Lee, Yin Hao, Tan, Nguan Soon, Loo, Say Chye Joachim

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Functional genomics reveals an off-target dependency of drug synergy in gastric cancer therapy by Leylek, Ozen, Honeywell, Megan E., Lee, Michael J., Hemann, Michael T., Ozcan, Gulnihal

“…However, realizing the full potential of this approach requires a clear comprehension of the genetic dependencies underlying drug synergy. …”
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Evaluation of paper spray mass spectrometry for direct analysis of small molecule drugs and hemoglobin constant spring peptide markers by Takyi-Williams, John

“…The studies described in this thesis were undertaken to evaluate the application of paper spray mass spectrometry for direct analysis of small molecule drugs and biomarker in dried matrix spot samples. …”
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Modular Titratable Polypills for Personalized Medicine and Simplification of Complex Medication Regimens by Karavasili, Christina, Babaee, Sahab, Kutty, Shruti, Chu, Jacqueline N., Min, Seokkee, Fitzgerald, Nina, Morimoto, Joshua, Inverardi, Nicoletta, Traverso, Giovanni

“…To fill the existing gap in drug dose personalization and simplification of complex medication regimens commonly encountered in the treatment of cardiovascular disease, tuberculosis, and tapering of corticosteroid therapy, a modular titratable polypill approach that simultaneously addresses both aspects is proposed. …”
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Investigation of blood pressure regulation schemes by Chai, Chang Yong

“…Hence, continuous monitoring and careful control of the infusion of drug is required. Since the middle 1970s, many researches have been conducted using various types of feedback control system to regulate blood pressure through the infusion of antihypertension drug [5]. …”
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Interfacial phenomena and biological recognition of mammalian cells on biomimetic materials by Chan, Vincent.

“…We intend to fill this gap by interrogating the biophysical events involved in membrane-polymer interaction, biological adhesion, tissue engineering and cellular fluid mechanics. …”
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Cloud Spark Cluster to analyse English prescription big data for NHS intelligence by Fernando, Sandra, Sowinski-Mydlarz, Viktor, Virdee, Bal Singh

“…This study illustrates regions as well as GP practices in terms of reimbursement cost, drug consumption level, the type of the drug, and the disease type; varied demand for dispensed chemical substances over the years; shows what diseases have increased or decreased over the years as well as the total cost and its trends.…”
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Doxorubicin-loaded cell-derived nanovesicles: an alternative targeted approach for anti-tumor therapy by Goh, Wei Jiang, Lee, Choon Keong, Zou, Shui, Woon, Esther, Czarny, Bertrand, Pastorin, Giorgia

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Understanding the viral protein structures of clinically relevant arboviruses and fragment-based screening for antivirals by Farhana Abu Bakar

“…In recent years, antiviral drug discovery has increasingly relied on the use of high-resolution structural information of important viral proteins and have led to the development of potent inhibitors. …”
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Design, simulation, and testing of a low cost laser micromachining system for flexible and rapid tissue-on-chip fabrication. by Nin, Jorge A.

“…With fabrication times of 6-8 minutes for small features and less than an hour for a full chip, our method represents a significant advancement in rapid prototyping capabilities. …”
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Optimising expression and purification of Dengue soluble E protein by Poh, Nina Yong Xin

“…It offers insights into viral-host immune interactions. The full-length E protein is essential for vaccine design. …”
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Ion doping behavior of stöber silica-nanosynthesis and application by Song, Xiaohui

“…Besides, we can dope positive charged organic molecules inside silica nanoparticle, such as dyes, drugs, and so on. The above synthesis control is important to silica application in biosensors, drug delivery, catalysts, and battery. …”
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Association of current Schistosoma mansoni, Schistosoma japonicum, and Schistosoma mekongi infection status and intensity with periportal fibrosis: a systematic review and meta-ana... by Ewuzie, A, Wilburn, L, Thakrar, DB, Cheng, H, Reitzug, F, Roberts, N, Malouf, R, Chami, GF

“…Two reviewers independently screened abstracts and full-text reports for eligibility. A third reviewer was consulted in cases of disagreement. …”

Improving access to pulmonary rehabilitation for patients with COPD treated for substance misuse in the London Borough of Islington by Narasimhan, Divya, Simpson, Jane, Stewart, Duncan

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Barriers and leverage points for seeing alcohol differently in integrated care systems in England: a senior stakeholder interview study by Madden, Mary, Stewart, Duncan, McCambridge, Jim

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Delay-and-pay: prolonging pharmaceutical patent protection without paying the ‘price’ by Foss-Solbrekk, K

“…<p>This thesis argues that actors use the patent system as part of a ‘delay-and-pay’ strategy to preserve drug prices for as long as possible by delaying generic/biosimilar market entry – and that they have a significant incentive to do so. …”