Antitumor polycyclic acridines. 7. Synthesis and biological properties of DNA affinic tetra- and pentacyclic acridines by Stanslas, Johnson, Hagan, Damien J., Ellis, Michael J., Turner, Claire, Carmichael, James, Ward, Wynne, Hammonds, Timothy R., Stevens, Malcolm F. G.

“…The novel water-soluble agent dihydroindolizino[7,6,5-kl]acridinium chloride 14 has inhibitory activity in a panel of non-small-cell lung and breast tumor cell lines exceeding that of m-AMSA. The salt inhibited the release of minicircle products of kDNA confirming that disorganization of topoisomerase II partly underlies the activity of the compound. …”

Circularly polarized antennas and phased arrays for 5G applications by Hu, Yiyun

“…This unit is improved based on the off-center fed folded long dipole by introducing the half-ring structure, which could make the unit more suitable for beam scanning arrays. …”
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Jurisdictional approaches to high conservation value area designation using regulatory instruments: an Indonesian pilot project by Padmanaba, Michael, Sloan, Sean, Watts, John D., Irawan, Silvia, Lee, Janice Ser Huay, Pasaribu, Katryn N., Wiratama, Cokorda Gde Wisnu, Watson, Ellen, Utami, Nadia Putri

“…Likely HCV areas were generally similar between the ECCA and HCV Screening method, as each set spanned ∼90% of the district. However, higher-confidence HCV areas according to the ECCA were much less extensive, at 51% of the district, and uniquely extensive across oil-palm concessions. …”
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Nation in action : making Chinese in the rural borderland between China and North Korea by Chen, Shiwei

“…Data collection is based on multi-sited fieldwork over the span of three years, utilizing participant observation and in-depth interviews. …”
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Upper mantle rheology from GRACE and GPS postseismic deformation after the 2004 Sumatra-Andaman earthquake by Banerjee, Paramesh, Panet, I., Mikhailov, V., Diament, M., Grijalva, K., Pollitz, Fred F.

“…To fit the remaining misfit to the GRACE data, larger at the smaller spatial scales, cumulative afterslip of about 75 cm at depth should be added over the period spanned by the GRACE models. It produces only small crustal displacements. …”
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Remote digital cognitive assessment reveals cognitive deficits related to hippocampal atrophy in autoimmune limbic encephalitis: a cross-sectional validation study by Shibata, K, Attaallah, B, Tai, X-Y, Trender, W, Hellyer, PJ, Hampshire, A, Irani, SR, Manohar, SG, Husain, M

“…No impairments in digit & spatial span, target detection (attention) and emotion discrimination were observed. …”

Cellular reporter for inflammation. by Yuhanis Abdullah Sunny.

“…Currently, there are commercial green fluorescent protein (GFP) assays available for in vitro cell lines only. There are no in vivo systems that can report NF-B activation in hematopoietic stem cells. …”
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Laser surface treatment of 50CrMo4 steel by Chew, Han Xin

“…The speed of laser is significance in affecting the width and depth of the laser treated lines. When the speed is too high, the change is not visible, thus, the hardness test cannot be done on the cross section area.…”
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Database and Application Programming Interface Development for Rotational Spectroscopy by Cheung, Jasmine So Yee

“…A database of spectroscopic data serves as the foundation of the automation pipeline for assigning spectral lines to species. While there are existing databases available for use, we developed our custom database, named SAAGAdb, and an application programming interface (API) to access the database to fulfill the needs of SAAGA. …”
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Cytotoxic triosmium carbonyl clusters : a structure-activity relationship study by Top, Siden, Vessières, Anne, Leong, Weng Kee, Lee, Shirley Hui Zhi

“…In vitro evaluation of these new compounds showed that some are selectively active against estrogen receptor (ER)-independent MDA-MB-231 breast cancer cell lines relative to ER-dependent MCF-7 breast cancer cells, suggesting that the compounds have a different biological target specific to MDA-MB-231 cells. …”
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An iGlu receptor antagonist and its simultaneous use with an anticancer drug for cancer therapy by Luo, Zhong, Li, Peizhou, Tan, Si Yu, Ang, Chung Yen, Nguyen, Kim Truc, Zhao, Yanli

“…In vitro studies on B16F10 and NIH3T3 cell lines revealed that the iGlu receptor antagonist L1 exhibited therapeutic as well as targeting effects. …”
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Extensive promoter-centered chromatin interactions provide a topological basis for transcription regulation by Li, Guoliang, Ruan, Xiaoan, Auerbach, Raymond K., Sandhu, Kuljeet Singh, Zheng, Meizhen, Wang, Ping, Poh, Huay Mei, Goh, Yufen, Lim, Joanne, Zhang, Jingyao, Sim, Hui Shan, Peh, Su Qin, Mulawadi, Fabianus Hendriyan, Ong, Chin Thing, Orlov, Yuriy L., Hong, Shuzhen, Zhang, Zhizhuo, Landt, Steve, Raha, Debasish, Euskirchen, Ghia, Wei, Chia-Lin, Ge, Weihong, Wang, Huaien, Davis, Carrie, Fisher-Aylor, Katherine I., Mortazavi, Ali, Gerstein, Mark, Gingeras, Thomas, Wold, Barbara, Sun, Yi, Cheung, Edwin, Liu, Edison, Sung, Wing-Kin, Snyder, Michael, Ruan, Yijun, Fullwood, Melissa Jane

“…Comparative analyses of different cell lines showed that cell-specific chromatin interactions could provide structural frameworks for cell-specific transcription, and suggested significant enrichment of enhancer-promoter interactions for cell-specific functions. …”
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Investigating the content and function of stress-induced extracellular vesicles in colorectal cancer by Mason, J

“…Therefore, my DPhil focussed on investigating the potential pro-tumorigenic properties of these “switched” EVs in CRC cell lines in vitro and also assessing the composition of EVs in CRC patient plasma.…”

Neuroprotective effect of tocotrienol-rich fraction and a-tocopherol of vitamin E against glutamate toxicity in neuronal cells and astrocytes by Selvaraju, Thilaga Rati

“…In this study, the effects of vitamin E when supplemented before (pre-treatment) and after (post-treatment) glutamate insult were elucidated in neuronal and astrocyte cell lines. The neuroprotective effect of TRF and α-TCP were investigated. …”
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Design and investigation of block copolymers for dispersion of carbon nanotubes in polymer matrices by Liu, Chengyin

“…To further improve the tensile properties of the SWNTs/epoxy nanocomposites, we fabricated another series of PI-derived block copolymers via ring-opening polymerization initiated from hydroxyl-terminated polyimide of lactide and allyl-bearing 2-methyl-2-(allyloxycarbonyl)propylene carbonate) (MAC) to produce PLA-b-PI-b-PLA (TB1) and PMAC-b-PI-b-PMAC (TB2) which are polyester and poly(ester-carbonate)-derived, respectively. …”
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Structure and functions of a metallo-beta-lactamase- like hypothetical protein bleg1_2437 from alkali-tolerant soil bacterium Bacillus lehensis G1 by Tan, Soo Huei

“…However, the emergence of antibiotic resistance mechanism among pathogenic bacteria has downsized the efficacy of antibiotics via the production metallo-β-lactamase (MBL) which enables pathogens to destroy the β- lactam ring of β-lactam antibiotics. Although MBL is not ubiquitously found in all pathogenic bacteria, its presence is a public health concern. …”
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Serial interconnections of 1-contracting and 2-contracting systems by Ofir, Ron, Margaliot, Michael, Levron, Yoash, Slotine, Jean-Jacques

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Assessing the financial performance of container shipping companies by Shen, Wanling.

“…Five companies were shortlisted from the top 30 container shipping lines, where trends and changes in five selected indicators were analyzed over a specified timeframe before and after integration. …”
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Targeted therapy to gastric cancer by Hou, Qian.

“…In this study, 17 gastric cancer cell lines were used to screen a library of 60 small molecule inhibitors and chemotherapy drugs for discovery of potential therapeutic agent by methyl thiazole tetrazolium (MTT) assays. 8 effective drugs which include Docetaxel, Paclitaxel, 17-DMAG, Bortezomib, Calyculin A, Okadaic acid, Staurosporine and Bafilomycin A1 were identified and subject to further characterization by IC50 calculation, cell migration assay, morphology study and cell cycle analysis by FACS. …”
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Reconfigurable antennas for GSM and WLAN applications by IHD Mavidu Nipunath Iddagoda

“…A prototype antenna was fabricated with commercially available diodes used for switching between the two frequency bands. DC biasing lines were drawn from the top surfaces of the nested antenna. …”
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