Butelase 1: A Versatile Ligase for Peptide and Protein Macrocyclization by Nguyen, Giang Kien Truc, Kam, Antony, Tam, James Pingkwan, Loo, Shining, Jansson, Anna Elisabet, Pan, Lucy Xin

“…Here we report a highly efficient method using butelase 1 to macrocyclize peptides and proteins ranging in sizes from 26 to >200 residues. …”
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2-amino-5-chloropyrimidin-1-ium hydrogen maleate by Fun, Hoong-Kun., Hemamalini, Madhukar., Rajakannan, Venkatachalam.

“…In the title salt, C4H5ClN3+·C4H3O4-, the 2-amino-5-chloropyrimidinium cation is protonated at one of its pyrimidine N atoms. In the roughly planar (r.m.s. deviation = 0.026 Å) hydrogen malate anion, an intramolecular O-HO hydrogen bond generates an S(7) ring. …”
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Kalman filtering with scheduled measurements - part I : estimation framework by You, Keyou, Xie, Lihua

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Proceedings of Data Analytics and Management: ICDAM 2023, Volume 1

Perturbed hematopoiesis in the Tc1 mouse model of Down syndrome by Alford, KA, Slender, A, Vanes, L, Li, Z, Fisher, EMC, Nizetic, D, Orkin, SH, Roberts, I, Tybulewicz, VLJ

“…TMD and DS-AMKL almost always carry an acquired mutation in GATA1 resulting in exclusive synthesis of a truncated protein (GATA1s), suggesting that both trisomy 21 and GATA1 mutations are required for leukemogenesis. …”

Preclinical development of antisense conjugates for the treatment of myotonic dystrophy 1 by Stoodley, J

“…</p> <p>To address the challenge of CNS delivery in DM1, I also tested the potential of ASO conjugation to a CNS optimized, anti-transferrin receptor 1 (anti-TfR1)- targeting antibody. …”

Transport and inhibition of the sphingosine-1-phosphate exporter SPNS2 by Li, HZ, Pike, ACW, Chang, Y, Prakaash, D, Gelova, Z, Stanka, J, Moreau, C, Scott, HC, Wunder, F, Wolf, G, Scacioc, A, McKinley, G, Batoulis, H, Mukhopadhyay, S, Garofoli, A, Pinto-Fernández, A, Kessler, BM, Burgess-Brown, NA, Štefanić, S, Wiedmer, T, Dürr, KL, Puetter, V, Ehrmann, A, Khalid, S, Sauer, DB

“…Sphingosine-1-phosphate (S1P) is a signaling lysolipid critical to heart development, immunity, and hearing. …”

Role of the collagen receptor DDR1 in epithelial morphogenesis and polarisation by Søgaard, P

Subjects:

PIERCE1: a determinant of left-right asymmetry in mammals by Farley, H

“…Transmission electron microscopy studies point towards a role for PIERCE1 in the assembly or trafficking of dynein arms and their components; however, protein interaction studies have proved inconclusive thus far at placing PIERCE1 within the network of known dynein arm assembly factors.…”

Within-host evolution of HIV-1 and the analysis of transmissible diversity by English, SE

“…I explain how the experimental data that I have generated and the analyses I have carried out address certain basic assumptions and predictions about HIV-1 transmission and may inform current strategies for vaccine design. …”

Pasukan Olahraga UPM Juara VTF SIRKIT 1 2024 by Universiti Putra Malaysia, .

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Analyses of human vaccine-specific circulating and bone marrow-resident B cell populations reveal benefit of delayed vaccine booster dosing with blood-stage malaria antigens by Barrett, JR, Silk, SE, Mkindi, CG, Kwiatkowska, KM, Hou, MM, Lias, AM, Kalinga, WF, Mtaka, IM, McHugh, K, Bardelli, M, Davies, H, King, LDW, Edwards, NJ, Chauhan, VS, Mukherjee, P, Rwezaula, S, Chitnis, CE, Olotu, AI, Minassian, AM, Draper, SJ, Nielsen, CM

“…Notably, a higher frequency of vaccine-specific (putatively long-lived) plasma cells was detected in the bone marrow of these delayed boosting vaccinees by ELISPOT and correlated strongly with serum IgG. …”

Human Wharton's jelly mesenchymal stem cells show unique gene expression compared with bone marrow mesenchymal stem cells using single-cell RNA-sequencing by Barrett, Angela N., Fong, Chui-Yee, Subramanian, Arjunan, Liu, Wenting, Feng, Yirui, Choolani, Mahesh, Biswas, Arijit, Rajapakse, Jagath Chandana, Bongso, Ariff

“…Their broad differentiation potential, high rate of proliferation, ready availability from discarded cords, and prolonged maintenance of stemness properties in culture make them an attractive alternative source of MSCs with therapeutic value compared with human bone marrow MSCs (hBMMSCs). We aimed to characterize the differences in gene expression profiles between these two stem cell types using single-cell RNA sequencing (scRNA-Seq) to determine which pathways are involved in conferring hWJSCs with their unique properties. …”
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One-Step Replica Symmetry Breaking of Random Regular NAE-SAT II by Nam, Danny, Sly, Allan, Sohn, Youngtak

“…Continuing our earlier work in Nam et al. (One-step replica symmetry breaking of random regular NAE-SAT I, <jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://arxiv.org/abs/2011.14270">arXiv:2011.14270</jats:ext-link>, 2020), we study the random regular <jats:italic>k</jats:italic>-<jats:sc>nae-sat</jats:sc> model in the condensation regime. …”
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No One Wants To Be A Parasitologist: The Shrinking Field of America's Least Favorite Animals by Richter, Hannah

“…While parasites can cause horrible human suffering, especially in countries without reliable clean water or sanitation systems, only a fraction of parasites affect humans, with estimates as low as 0.1%. As climate change and habitat loss threaten animals, so too do they endanger the parasites that live on and inside them. …”
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Portia: It is Not a "Crisis Committee," But One Might Want a "Portia" Anyway by Rowe, Mary

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A family of curves for the geometric mean distance of one rectangle from another by Uluant, Cemal Ali.

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Pick one, but be quick : 5' splice sites and the problems of too many choices by Roca, Xavier, Krainer, Adrian R., Eperon, Ian C.

“…We also discuss recent work demonstrating that U1 snRNA:5′ss helices can accommodate noncanonical registers such as bulged duplexes. …”
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Finite volume method for one-dimensional heat conduction in functionally graded materials by Soh, Nicholas

“…The finite volume method (FVM), which is used to study a functionally graded one-dimensional study on a material, is considered by the theoretical framework. …”
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AI based failure analysis for one type of switch gears in power systems by Zhang, Qingquan

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