Development of an inhibitor of the mutagenic SOS response that suppresses the evolution of quinolone antibiotic resistance by Bradbury, JD, Hodgkinson, T, Thomas, AM, Tanwar, O, La Monica, G, Rogga, VV, MacKay, LJ, Taylor, EK, Gilbert, K, Zhu, Y, Sefton, AY, Edwards, AM, Gray-Hammerton, C, Smith, GR, Roberts, P, Walsh, TR, Lanyon-Hogg, T

“…Small molecules, such as IMP-1700, potentiate DNA damage and inhibit the SOS response in methicillin-resistant S. aureus; however, understanding of the structure–activity relationship (SAR) of this series is lacking. We report here the first comprehensive SAR study of the IMP-1700 scaffold, identifying key pharmacophoric groups and delivering the most potent analogue reported to date, OXF-077. …”

Harnessing novel strategies and cell types to overcome immune tolerance during adoptive cell therapy in cancer by Neo, Shi Yong, Xu, Shengli, Chong, Joni, Lam, Kong-Peng, Wu, Jing

“…We discuss recent advances in various types of cell therapies, including T cell receptor-T cells, chimeric antigen receptor (CAR)-T cells, tumor-infiltrating lymphocytes and natural killer cells. …”
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Video surveillance for intelligent transportation system by Liu, Jiamin

“…We are presenting a way to robustly detect the real-time traffic flowrate and classify the vehicle type (bus, car, motorbike) using basic video processing technologies from a surveillance camera video input. …”
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Internet stock trading : a study on the current developments and implications for future growth by Lee, James Chih Hui, Wan, Qian Wen, Lim, Bee Peng

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Evaluation of Singapore as an association hub. by Ho, Aileen Yee Pei., Lim, Ee Jin., Tang, Michelle Bee Shan.

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Impact of electronic commerce on consumer behaviour and attitude in Singapore. by Seah, Judy Bee Woon.

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Information needs of prospective students to New Zealand by Chuah, Joo Bee.

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The relationship between industry profit and interest rate in Singapore : an exploratory study. by Chia, Min Liang., Lim, Daphne Bee Kuan., Yip, Wei-Jen.

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The role and influence of service quality on the business of provision stores. by Lui Woon Kuan, Sim Hui Ling, Yeo Siew Bee

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Challenges of a New Zealand information communication technology company in the call center business. by Chua, Bee Luan., Lim, Chooi Hoe., Ng, Ginny Tuan., Yeo, Khee Teck.

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Factors affecting longevity of foreign direct investments. by Chua, Pamela Wan Leng., Kwek, Yi Shin., Ng, Bee Keng.

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Effective communication of low probabilities by Chai, Khai Shin, Koh, Angela Bee Lin, Lee, Yen Teik

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Scope, characteristics, behavior change techniques, and quality of conversational agents for mental health and well-being: systematic assessment of apps by Lin, Xiaowen, Martinengo, Laura, Jabir, Ahmad Ishqi, Ho, Andy Hau Yan, Car, Josip, Atun, Rifat, Tudor Car, Lorainne

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Audit quality : practice review by Leow, May Cin, Lim, Joo Kiow, Seah, Bee Cheng

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Inferior market performance of initial public offerings issued by family firms : myth or reality? by Lee, Jimmy Kiat Bee., Ng, Tuck Whye., Wong, Manquan.

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Focused strategy and advantage in the telecommunications equipment industry by Pek, Ruoh Han, Aw, Bee Huay, How, Janice Sui Yen

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Connecting the dots: the state of arts and health in Singapore by Tan, Michael Koon Boon, Tan, Chao Min, Tan, Soon Guan, Yoong, Joanne, Gibbons, Brent

“…Results: We find that the field in Singapore is rapidly growing, with a proliferation of activities across the arts and culture, healthcare, and social care sectors in recent decades fostered by various policy developments, increased funding and new peer-to-peer networking. Nevertheless, several issues persist, including inconsistent understanding and conceptualisation of the field as a whole across multiple stakeholders, limited research capacity and training platforms, and lack of professional recognition. …”
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Cytotoxic triosmium carbonyl clusters : a structure-activity relationship study by Top, Siden, Vessières, Anne, Leong, Weng Kee, Lee, Shirley Hui Zhi

“…The SAR results showed that good solubility in DMSO and at least one vacant site are required for cytotoxicity. …”
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Singapore youth and their idols : celebrity workshop from a media and psychosocial perspective by Deng, Yihan, Lye, Peixian, Nai, Ying Jiin

“…This study examines the impact of media exposure (TV, radio, internet, magazines) and psychosocial factors such as self-esteem, emotional autonomy and peer attachment on celebrity worship levels among Singaporean adolescents and includes gender and academic stream of study as control variables.…”
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Implementation of reinforcement learning using neural networks by Tan, Keng Hui

“…Reinforcement learning can be used to train machine to do our daily job such as cleaning the house, driving the car and may even one day breach into the manufacturing world.…”
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