Proteomic and metabolomic analyses of the human adult myocardium reveal ventricle-specific regulation in end-stage cardiomyopathies by Hunter, B, Li, M, Parker, BL, Koay, YC, Harney, DJ, Pearson, E, Cao, J, Chen, GT, Guneratne, O, Smyth, GK, Larance, M, O’Sullivan, JF, Lal, S

“…Inter-ventricular significance of these metabolic pathways was then found to be diminished within end-stage dilated cardiomyopathy and ischaemic cardiomyopathy, while heart failure-associated pathways were increased in the left ventricle relative to the right within ischaemic cardiomyopathy, such as fluid sheer-stress, increased glutamine-glutamate ratio, and down-regulation of contractile proteins, indicating a left ventricular pathological bias.…”

Large scale paired antibody language models by Kenlay, H, Dreyer, FA, Kovaltsuk, A, Miketa, D, Pires, D, Deane, CM

“…With the advent of next-generation sequencing, billions of antibody sequences have been collected in recent years, though their application in the design of better therapeutics has been constrained by the sheer volume and complexity of the data. To address this challenge, we present IgBert and IgT5, the best performing antibody-specific language models developed to date which can consistently handle both paired and unpaired variable region sequences as input. …”

Battery operated portable fridge by Ng, Chun Kiat.

Get full text

Quality over quantity: powering neuroimaging samples in psychiatry by Makowski, C, Nichols, TE, Dale, AM

“…In this review, we encourage this discourse to shift from a focus on sheer increases in sample size to more thoughtful choices surrounding experimental study designs. …”

Random by Koh, Bryan Theng Hui, Chan, Melody, Tang, Weixin

Get full text

Ancient Art, Modern Tech: Experiencing the Digital Reinvention of the Mogao Grottoes by Zhao, Celina

“…But now it must confront the greatest challenge to its continued existence: modern-day tourism. The sheer volume of visitors seeking a direct experience of this unique but delicate site has resulted in an increasingly rapid process of destruction in the 21st century. …”
Get full text
Get full text

Wind tunnel design and fabrication for lift force investigation by Kong, Shao Ming

“…As wind tunnels are resource intensive equipment, its potential as a learning aid is greatly hampered due to the sheer cost and logistics involved in the operation of a full sized wind tunnel. …”
Get full text

Ig.n.is. by Ong, Jian'an.

“…This spectrum does not appear suddenly, nor was it by sheer chance. There is a cascading effect on successive development of thought and spirituality that led to where we are, who we are, and why do we behave the way we do.…”
Get full text

Aggregating and analyzing Indian political tweets by Chirag Ruhela

“…Understanding this huge data-set in its raw form is not possible due to the sheer dimensionality of the data-set. Thus dimensionality reduction and clever insightful visualizations are needed to make this data consumable for general public. …”
Get full text

Developement of electrical equivalent circuit for super capacitor by Muhammad Bukhari Amiruddin.

Get full text

Battery reliability balancing by Tan, Yong Quan.

Get full text

Thermoelectric refrigerator by Keh, Yao Long.

Get full text

Development of load balancing technology for high power LED modules with constant current source by Zhong, Lidong

Get full text

《回味》= After taste by Lau, Chong Wai, Ng, Rebecca Yihui, Sim, Yu Ling

Get full text

Edge/cloud resource management for time-sensitive applications by Lim, Her Huey

“…Technological advancements and skyrocketing interest in areas such as Artificial Intelligence and Internet of Things as well as the sheer increase in development of software solutions, tools, infrastructure, and more have driven demand for cloud resources to staggering heights. …”
Get full text

SyROCCo: enhancing systematic reviews using machine learning by Fang, Z, Arana-Catania, M, van Lier, F-A, Outes Velarde, J, Bregazzi, H, Airoldi, M, Carter, E, Proctor, R

“…The sheer number of research outputs published every year makes systematic reviewing increasingly time- and resource-intensive. …”

Plastic heat sink by Tan, Cornelius Ming Han.

Get full text

Double trouble by Bay, Gladys Yun Ting, Wynn, Thant Sinn Halyn, Soh, Jovina Chui Ling, Loo, Sean Jia Jie

Get full text

Material extrusion-based printing optimization of recycled HDPE filaments made from used milk jugs by Teng, Phillis Soek Po, Tee, Chor Hiong, Tan, Hwee Boon, Leong, Kah Fai

“…High-density polyethylene (HDPE) is a widely used thermoplastic material for product packaging. The sheer availability of recyclable or recycled HDPE (rHDPE) from used packaging has led to efforts to apply it in MEX printing. …”
Get full text

HIV decision support : from molecule to man by Sloot, Peter M. A., Coveney, P. V., Muller, V., Boucher, Charles A. B., Ertaylan, Gokhan, Bubak, Marian

“…Effective highly active antiretroviral therapy and the availability of genetic screening of patient virus data have led to sustained viral suppression and higher life expectancy in patients who have been infected with HIV. The sheer complexity of the disease stems from the multiscale and highly dynamic nature of the system under study. …”
Get full text
Get full text