Large scale paired antibody language models by Kenlay, H, Dreyer, FA, Kovaltsuk, A, Miketa, D, Pires, D, Deane, CM

“…With the advent of next-generation sequencing, billions of antibody sequences have been collected in recent years, though their application in the design of better therapeutics has been constrained by the sheer volume and complexity of the data. To address this challenge, we present IgBert and IgT5, the best performing antibody-specific language models developed to date which can consistently handle both paired and unpaired variable region sequences as input. …”

Quality over quantity: powering neuroimaging samples in psychiatry by Makowski, C, Nichols, TE, Dale, AM

“…In this review, we encourage this discourse to shift from a focus on sheer increases in sample size to more thoughtful choices surrounding experimental study designs. …”

Contractor Learning and Home Energy Efficiency in Heat Pump Installations by Ontiveros, Johnattan H.

“…This learning impact is strongest for homes with a natural gas backup heater, which is the cheapest source of heating in Massachusetts followed by electric heat pump heating. …”
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Instrumentation optimisation for unicompartmental knee replacement by Arthur, LW

“…To minimise the risk of bearing fracture in the very long-term, surgeons should position the bearing close to the tibial wall, neutrally align the femoral component, and avoid using the thinnest Size 3 bearings in young patients.…”

Pushing the limits of relaxation and modulated-bath AC calorimetry. by Song, Zhibo.

“…This design also has the advantage that the DC offset which plagues conventional AC calorimeter can be eliminated by superposing an AC plus DC current supply to the joule heater. The detailed design of this calorimeter is investigated and the full working principle is explained. …”
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Study on structural robustness to resist progressive collapse of vertical irregularly base-isolated structures by Bao, Chao, Ma, Xiaotong, Lv, Dahai, Wu, Qiaozhi, Doh, Shu Ing, Chin, Siew Choo, Shu, Hongbo, Nor Hayati, Abdul Hamid

“…It is suggested that reasonable protection measures should be set for the isolation bearing with greater vulnerability coefficient which may suffer from extreme accidents and the potential risk of isolation bearing with greater component importance coefficient is eliminated or reduced.…”
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Study on mechanism and influential factors of progressive collapse resistance of base-isolated structure by Bao, Chao, Zhang, Yuhang, Lv, Dahai, Wang, Huxiang, Ma, Xiaotong, Cao, Jixing, Lim, Kar Sing

“…In the case of side isolation bearing failure, due to the lack of sufficient lateral restraint, the capacity was significantly lower than other conditions, which were more likely to cause partly collapse. …”
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Ancient Art, Modern Tech: Experiencing the Digital Reinvention of the Mogao Grottoes by Zhao, Celina

“…But now it must confront the greatest challenge to its continued existence: modern-day tourism. The sheer volume of visitors seeking a direct experience of this unique but delicate site has resulted in an increasingly rapid process of destruction in the 21st century. …”
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Design, synthesis, characterization and property study of topological structures of DNA by Li, Dawei

“…It is demonstrated in the current studies for the first time that the shapes of DNA writher (toroidal and interwound forms) can be precisely created sheerly through maneuvering the sequence of DNA and with no involvement of topological enzymes. …”
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Study of a dry fixed-vane revolving compressor by Toh, Shaun Jia Hui

“…However, when using sealed thrust bearings at the end-face and sealed roller bearings at the shaft-journal-support, results proved similar to lubricated values of power friction losses. …”
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Development of PCM-cooled helmet by Sua, Chong Chai.

“…The PCM-cooled helmet is tested in a wind tunnel at different wind speeds. Heater is used to simulate the heat generated by wearer’s head and heat radiator is used to create the solar radiation effect. …”
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Wind tunnel design and fabrication for lift force investigation by Kong, Shao Ming

“…As wind tunnels are resource intensive equipment, its potential as a learning aid is greatly hampered due to the sheer cost and logistics involved in the operation of a full sized wind tunnel. …”
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Ig.n.is. by Ong, Jian'an.

“…This spectrum does not appear suddenly, nor was it by sheer chance. There is a cascading effect on successive development of thought and spirituality that led to where we are, who we are, and why do we behave the way we do.…”
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Aggregating and analyzing Indian political tweets by Chirag Ruhela

“…Understanding this huge data-set in its raw form is not possible due to the sheer dimensionality of the data-set. Thus dimensionality reduction and clever insightful visualizations are needed to make this data consumable for general public. …”
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Influence of shear stress on cyclic behavior of marine sand by Kim, Jin Man, Safdar, Muhammad, Son, Su Won

“…Static and cyclic bearing capacity of marine soil is important for design of offshore wind turbine foundation. …”
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Large-scale model testing of high-pressure grouting reinforcement for bedding slope with rapid-setting polyurethane by Zhang, Zhichao, Tang, Xuefeng, Liu, Kan, Ye, Longzhen, He, Xiang

“…This study proposes an innovative polymer grout method to improve the bearing capacity and reduce the displacement of bedding slopes. …”
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IS activity in Southeast Asia by Liow, Joseph Chinyong, Liow Chin Yong, Joseph

“…The increasing number of recruits from Indonesia and Malaysia to Islamic State reflects the evolving security threat to Southeast Asia. The emerging pattern bears lessons for countries in the region.…”
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Modeling of formation and breaking of lubricant bridge in the head–disk interface by molecular dynamic simulation by Dai, Xiangyu, Li, Hui, Lei, Xiao, Shen, Shengnan, Wu, Shijing, Liu, Sen, Du, Hejun

“…And the duration of lubricant bridge is notably affected by heating-up time, rotation speed and bearing pressure. A shorter heating-up time leads to a longer duration of lubricant bridge, whereas a higher rotation speed and bearing pressure reduces the duration of lubricant bridge.…”
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Material extrusion-based printing optimization of recycled HDPE filaments made from used milk jugs by Teng, Phillis Soek Po, Tee, Chor Hiong, Tan, Hwee Boon, Leong, Kah Fai

“…High-density polyethylene (HDPE) is a widely used thermoplastic material for product packaging. The sheer availability of recyclable or recycled HDPE (rHDPE) from used packaging has led to efforts to apply it in MEX printing. …”
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A 2'-alkynylnucleotide strategy for site-directed spin labelling of DNA by Haugland, M

“…Herein is also outlined the preparation of azide-bearing nitroxyl radicals. After site-selective incorporation of 2'-alkynylnucleosides into DNA using a standard solid-supported phosphoramidite protocol, the modified oligonucleotides were spin labelled with the azide-bearing nitroxyl spin labels via the Cu(I)-catalysed azide-alkyne [3+2] Huisgen cycloaddition (CuAAC or 'click' reaction). …”