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    Cognitive Effects of Simulated Galactic Cosmic Radiation Are Mediated by ApoE Status, Sex, and Environment in APP Knock-In Mice by Wieg, Laura, Ciola, Jason C., Wasén, Caroline C., Gaba, Fidelia, Colletti, Brianna R., Schroeder, Maren K., Hinshaw, Robert G., Ekwudo, Millicent N., Holtzman, David M., Saito, Takashi, Sasaguri, Hiroki, Saido, Takaomi C., Cox, Laura M., Lemere, Cynthia A.

    Published 2024
    “…Here, we investigated the central nervous system (CNS) effects of 0 Gy (sham) or 0.75 Gy five-ion GCRsim or 2 Gy gamma radiation (IRR) in 14-month-old female and male APP<sup>NL-F/NL-F</sup> knock-in (KI) mice bearing humanized ApoE3 or ApoE4 (APP;E3F and APP;E4F). …”
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