Synthesis resolution of 3,4,3'4'-tetramethoxyl-1,1'-1,2,3,4-tetrahydrobisisoquinoline and application in asymmetric alkylation reactions by Almeida Hazel Virgilia Ann

“…This report describes the synthesis of chiral 3,4,3',4'-tetramethoxyl-1,1'-1,2,3,4-tetrahydrobisisoquinoline. The compound is to be later used as a catalyst in the asymmetric alkylation addition reaction between 2-propargyl acetate and benzaldehyde to form an allylic alcohol. …”
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Effect of inflammation on apolipoprotein A-1(apoA-1) secretion by intestinal cells. by Yu, Kenneth.

“…In contrast, pro-inflammatory drugs such as lipopolysaccharides and endotoxin appeared to decrease intestinal secretion of apoA-1. These results indicate that aspirin and paracetamol, two of the most widely used medications for fevers and headaches, may have beneficial effects on the metabolism of high-density-lipoproteins(HDL),the so-called" good cholesterol" by increasing the rate of apoA-1 secretion by the intestine. …”
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Molecular study of Rasd1 transcriptional regulation and Rasd1-NonO interaction. by Ong, Angeline Shufen.

“…I also find that Dbp enhances Rasd1 promoter activity by binding to the CCAAT/enhancer binding protein beta (C/EBPβ) site located at the 5’ untranslated region (UTR) of Rasd1. …”
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Trifluoroacetic acid as a molecular probe for the dense phase in liquid-liquid phase-separating peptide systems by Lim, Jessica, Chin, Sze Yuet, Miserez, Ali, Xue, Kai, Pervushin, Konstantin

“…We show that TFA can be employed to probe specific interactions in coacervating bioinspired peptide phenylalanine (Phe) 19F-labeled at a single site, altering its liquid-liquid phase separation (LLPS) behavior. …”
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The classification of 1D `perovskites' by Wong, Walter Pei De, Hanna, John V., Grimsdale, Andrew C.

“…The classification of perovskites has been unambiguous in the discussion of 3D and layered 2D perovskites due to the dimensional constraints. However, in 1D perovskites, the additional degrees of freedom have resulted in a large number of possible structural configurations. …”
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When I say … privilege by Cleland, Jennifer, Razack, Saleem

“…In the latest instalment of “When I Say…” Cleland and Razack argue it is time for medical education to acknowledge its complicit participation in socially constructed privilege and systemic inequalities and commit to change.…”
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Metaverse for virtual education 1 by Lau, Wynne Chen Yi

“…Several studies have indicated that the use of higher quality VR equipment provides a more immersive experience for its users, however, not all education institutes have the budget to invest in the more expensive and higher quality VR equipment for every one of their students. Hence, this project focuses on the development of a metaverse prototype for applications in virtual education to help educational institutes manage the use of the limited amount of VR equipment. …”
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Tangible Video Communication 1 by Yang, Fan

“…The key parts in the development phase are (1) establishing a network connection and (2) generating an efficient haptic rendering algorithm. (1) is used to solve the task of data transmission, while (2) is used to compute feedback force applied to haptic devices. …”
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Visualising mathematics for little ones by Tho, Shi Yee

“…This project is an exploration on children’s interests towards mathematics as a subject. I used to fair badly in mathematics until I received help from a tutor who made sure I fully understood the basic concepts. …”
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EV Myvi emo-1 by Ridzuan, Lizam

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Crystal Engineering of a Two-Dimensional Lead-Free Perovskite with Functional Organic Cations by Second-Sphere Coordination by Cortecchia, Daniele, Soci, Cesare, Cametti, Massimo, Petrozza, Annamaria, Martí-Rujas, Javier

Subjects: “…Hydrogen bonds…”
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Nanoarchitectonics-based model membrane platforms for probing membrane-disruptive interactions of odd-chain antimicrobial lipids by Yoon, Bo Kyeong, Tan, Sue Woon, Tan, Brenda Jia Ying, Jackman, Joshua A., Cho, Nam-Joon

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A Secure Digital In-Memory Compute (IMC) Macro with Protections for Side-Channel and Bus Probing Attacks by Ashok, Maitreyi, Maji, Saurav, Zhang, Xin, Cohn, John, Chandrakasan, Anantha P.

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Renal-clearable molecular probe for near-infrared fluorescence imaging and urinalysis of SARS-CoV-2 by Liew, Si Si, Zeng, Ziling, Cheng, Penghui, He, Shasha, Zhang, Chi, Pu, Kanyi

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Effect of early and later prone positioning on outcomes in invasively ventilated COVID-19 patients with acute respiratory distress syndrome: analysis of the prospective COVID-19 critical care consortium cohort study by Simpkin, AJ, McNicholas, BA, Hannon, D, Bartlett, R, Chiumello, D, Dalton, HJ, Gibbons, K, White, N, Merson, L, Fan, E, Panigada, M, Grasselli, G, Motos, A, Torres, A, Barbé, F, Ng, PY, Fanning, JP, Nichol, A, Suen, JY, Bassi, GL, Fraser, JF, Laffey, JG

“…We compared outcomes between patients prone positioned within 48 h of IMV to those (i) never proned, and (ii) proned only after 48 h. …”

Potent antimyeloma activity of the novel bromodomain inhibitors I-BET151 and I-BET762 by Chaidos, A, Caputo, V, Gouvedenou, K, Liu, B, Marigo, I, Chaudhry, M, Rotolo, A, Tough, DF, Smithers, NN, Bassil, AK, Chapman, TD, Harker, NR, Barbash, O, Tummino, P, Al-Mahdi, N, Haynes, AC, Cutler, L, Le, B, Rahemtulla, A, Roberts, I, Kleijnen, M, Witherington, J, Parr, NJ, Prinjha, RK, Karadimitris, A

“…Herein we expand the mechanistic understanding of BET inhibitors in multiple myeloma by using the chemical probe molecule I-BET151. I-BET151 induces apoptosis and exerts strong antiproliferative effect in vitro and in vivo. …”

Investigating ERO1α, IDO1 and MHC Class I : potential proteins that can be manipulated to change the tumour microenvironment from ‘cold’ to ‘hot’ by Peck, Jia Yi

“…ERO1α, a cancer-associated protein, and IDO1, an immunomodulatory enzyme, have been shown to be associated with the expression of MHC Class I proteins. …”
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Temperature-dependent ultrafast carrier and phonon dynamics of topological insulator Bi1.5Sb0.5Te1.8Se1.2 by Cheng, Liang, La-o-vorakiat, Chan, Tang, Chi Sin, Nair, Saritha K., Xia, Bin, Wang, Lan, Zhu, Jian-Xin, Chia, Elbert E. M.

“…Using ultrafast optical pump-probe technique, we studied the temperature-dependent carrier and phonon dynamics of the topological insulator Bi1.5Sb0.5Te1.8Se1.2 single-crystal from 10 K to 300 K. …”
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Green bonds : an introduction to a new market based approach in solving the regional haze crisis by Chew, John Han Hui, Chin, Yin Chai, Han, Kai Jie

“…Our paper explores the rationale for using Green Bonds over financial aid as well as explaining the details of the whole Green Bonds issuance process. …”
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Structural characterization of vaccinia-related kinase 1 (VRK1), a histone mitotic kinase by Ngow, Yeen Shian

“…To-date, the structural basis of VRK1-ATP interaction is not available, hindering the progress toward designing VRK1 specific Type I inhibitors. …”
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