Increased interleukin-6 correlates with myelin oligodendrocyte glycoprotein antibodies in pediatric monophasic demyelinating diseases and multiple sclerosis by Horellou, P, Wang, M, Keo, V, Chrétien, P, Serguera, C, Waters, P, Deiva, K

“…Acquired demyelinating syndromes (ADS) in children evolve either as a monophasic disease diagnosed as acute demyelinating encephalomyelitis (ADEM), transverse myelitis (TM) or optic neuritis (ON), or a multiphasic one with several relapses most often leading to the diagnosis of multiple sclerosis (MS) or neuromyelitis optica (NMO). …”

Nutraceuticals silybin B, resveratrol, and epigallocatechin-3 gallate-bind to cardiac muscle troponin to restore the loss of lusitropy caused by cardiomyopathy mutations in vitro,... by Yang, Z, Sheehan, AM, Messer, AE, Tsui, S, Sparrow, A, Redwood, C, Kren, V, Gould, IR, Marston, SB

“…Phosphorylation causes a 2-3 fold decrease of affinity of cTn for Ca2+ associated with a higher rate of Ca2+ dissociation from cTnC leading to a faster relaxation rate of the cardiac muscle (lusitropy). …”

Investigating the functional and metabolic role of carnitine in the diabetic heart using hyperpolarized MRI by Savic, D

“…<p>Diabetes increases the incidence of myocardial infarction and heart failure, which are leading causes of mortality in diabetic patients. …”

Investigation of soil-structure interaction for deep excavations by Hensman, P

“…The results can provide confidence in the use of numerical models for the design of future deep excavation structures, leading to cost and carbon savings through a reduction in required material quantities.…”

Enhancement of lentiviral vector production through alteration of virus-cell interactions by Gelinas, J

“…</p> <p>Further work will be necessary to understand the role of the inhibitory factors in lentiviral vector production, but novel cell lines in which genes encoding these factors have been permanently deleted from producer cells could lead to higher titres, reducing costs in the manufacture of lentiviral vectors and making <em>in vivo</em> gene therapy more feasible from a health economics perspective.…”

Monitoring and analysis of antenatal and postnatal changes in maternal vital signs by Pullon, R

“…</p> <p>The investigations in this thesis contribute additional knowledge of pregnancy-associated vital-sign changes, and lead to an initial proposal for an evidence-based obstetric early warning score specific to the stage of pregnancy.…”

Dose escalation pre-clinical trial of novel DOK7-AAV in mouse model of DOK7 congenital myasthenia by Cossins, J, Kozma, I, Canzonetta, C, Hawkins, A, Beeson, D, Sepulveda, P, Dong, YY

“…Mutations in this gene are one of the leading three most prevalent causes of congenital myasthenia in diverse populations across the globe. …”

Securing reform? Post-election power sharing and security sector reform in Zimbabwe, Kenya, and Togo, 2006-2013 by Noyes, A

“…</p> <p>As such, this dissertation seeks to answer the following questions: Does post-election power sharing lead to security sector reform? Which causal factors are most important in shaping security reform outcomes under post-election power sharing, and through what processes or mechanisms?…”

Mendelian randomization identifies proteins involved in neurodegenerative diseases by Belbasis, L, Morris, S, Van Duijn, C, Bennett, D, Walters, R

“…Evidence of co-localisation between plasma protein abundance and disease risk (posterior probability &gt;0.80) was identified for 61 proteindisease pairs, leading to 50 unique protein-disease associations. …”

“I believe it when there is an expert next to me:” a qualitative analysis on the perceptions and experiences of pregnant women to self-monitor blood pressure in Lombok, Indonesia... by Tamrat, T, Setiyawati, YD, Barreix, M, Madani, N, Geissbühler, A, Shankar, AH, Tuncalp, O

“…Background: Hypertensive disorders of pregnancy (HDP) are a leading cause of maternal deaths and require close monitoring of blood pressure (BP) to mitigate potential adverse effects. …”

Life cycle assessment of greenhouse gas emissions and carbon mitigation methods in probiotic-fed broiler production by Chin, H.W., Tee, T.P., Tan, N.P., Angkanaporn, Kris

“…Implementing sustainable agricultural practices could lead to more ecological poultry production, contributing to global efforts in climate change mitigation.…”

Knowledge, beliefs, perceptions and barriers related to implementing smoke-free home practices in two rural settlement areas in Malaysia by Kamni, Siti Nurhasyimah Ayuni, Saiful Bahron, Nur Ain Nadhirah, Zulkifli, Aziemah, Uny, Isabelle, O’Donnell, Rachel, Prabandari, Yayi Suryo, Bintoro, Bagas Suryo, Zainal Abidin, Emilia, Semple, Sean

“…INTRODUCTION Studies have found that parental smoking is the primary source of secondhand smoke (SHS) exposure among children, leading to respiratory illnesses, especially in non-smokers like children and women. …”
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Microplastics in urban soils from different land use activities of Cyberjaya (Malaysia): exploring occurrence, relationships, sources and pollution level by Praveena, Sarva Mangala, Nik Mohd Zaidi, Nik Munirah, Nafisyah, Ayu Lana, Lingaraju, H.G.

“…As human activities continue to increase, the production and utilisation of plastics have become pervasive, leading to a surplus of plastic waste in the environment. …”
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ESBL producing E. coli in chickens and poultry farms environment in Selangor, Malaysia: a cross-sectional study on their occurrence and associated risk factors with environment and... by Aliyu, Abdulrasheed Bello, Jalila, Abu, Saleha, Abdul Aziz, Zunita, Zakaria

“…Conclusions: Our study showed the presence and spread of ESBL EC among chickens in the farms and their environment; this may lead to being spread to outside of farm environment by flies, vermins, flying birds, litter and farm wastes and possibly to humans upon contact with the contaminated environment and by poultry meat. …”

Temporal disruption in tuberculosis incidence patterns during COVID-19: a time series analysis in China by Zhang, Jiarui, Sun, Zhong, Deng, Qi, Yu, Yidan, Dian, Xingyue, Luo, Juan, Karuppiah, Thilakavathy, Joseph, Narcisse, He, Guozhong

“…Conclusions: The COVID-19 pandemic has had a temporary but significant impact on PTB incidence in China, leading to a reduction in reported cases during the pandemic. …”
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Apoptotic-related signalling pathways in mcf-7 cells treated with ethyl acetate extract of dillenia suffruticosa, and isolation of its major compounds by Yin, Sim Tor

“…EADs was found to promote oxidative stress that will lead to cell death because the pre-treatment with antioxidants α-tocopherol and ascorbic acid significantly reduced the cytotoxicity of the extract (P<0.05). …”
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Ethanol sensor using tapered optical fiber coated with graphene-based nanomaterials by Girei, Saad Hayatu

“…Graphene and graphene oxide (GO) has emerged as a leading materials in wide variety of applications including chemical sensing due to its exceptional thermal, optical and mechanical properties. …”
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The effect of using individual self-guided Breathing controlled with imagery Training among novice and skill athletes by Roslan, Siti Raihanah

“…Trained breathing pattern in individual can have a profound effect on self regulation reducing anxiety, leading to enhanced performance. This study is to determine the effect of using self guided breathing control with imagery training on novice and Netball skilled athletes(SA). …”
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A recent development on core-shell-based material and their application in membranes for water and wastewater treatment by Dinia Astira, Dinia Astira, Abdullah, Romario, Widyanto, Alvin Rahmad, Cipta Dharma, Hadi Nugraha, Santoso, Liangga, Sulistiono, Dety Oktavia, Zeni Rahmawati, Zeni Rahmawati, Gunawan, Triyanda, Jaafar, Juhana, Othman, Mohd Hafiz Dzarfan, Ratna Ediati, Ratna Ediati, Muhammad Hasan, Muhammad Hasan, Fansuri, Hamzah

“…The enhanced filler dispersion and matrix stability lead to the high permeation flux and selectivity. …”

Design and analysis of high torque density machines for aerospace applications by Shen, Fawen

“…To reveal the impact of key parameters on torque performances, the parametric optimization of the UV-FSPM is carried out. The leading performances of three FSPMs are comparatively studied by FEA. …”
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