Nutraceuticals silybin B, resveratrol, and epigallocatechin-3 gallate-bind to cardiac muscle troponin to restore the loss of lusitropy caused by cardiomyopathy mutations in vitro,... by Yang, Z, Sheehan, AM, Messer, AE, Tsui, S, Sparrow, A, Redwood, C, Kren, V, Gould, IR, Marston, SB

“…Further molecular dynamics simulations could define the specific properties needed for recoupling and allow for the prediction and design of potential new drugs.…”

Ion doping behavior of stöber silica-nanosynthesis and application by Song, Xiaohui

“…Besides, we can dope positive charged organic molecules inside silica nanoparticle, such as dyes, drugs, and so on. The above synthesis control is important to silica application in biosensors, drug delivery, catalysts, and battery. …”
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Application of in vitro erythropoiesis from bone marrow derived progenitors to detect and study genotoxicity by Shuga, Joseph F. (Joseph Francis)

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Association of current Schistosoma mansoni, Schistosoma japonicum, and Schistosoma mekongi infection status and intensity with periportal fibrosis: a systematic review and meta-ana... by Ewuzie, A, Wilburn, L, Thakrar, DB, Cheng, H, Reitzug, F, Roberts, N, Malouf, R, Chami, GF

“…Two reviewers independently screened abstracts and full-text reports for eligibility. A third reviewer was consulted in cases of disagreement. …”

Breaking permutation-based mesh steganography and security improvement by Wang, Yimin, Kong, Lingsheng, Qian, Zhenxing, Feng, Guorui, Zhang, Xinpeng, Zheng, Jianmin

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Fictions of youth: childness in selected West African novels, 1991-2009 by Moellenberg, T

“…A "child" here is defined as a human person under age 18 and is referred to using the term <em>childness</em>, drawing from the work of children's literature scholar Peter Hollindale. …”

Determination of operating point for a propulsive wing UAV using CFD by Chan, Chee Shuan

“…CFD simulations were performed using a 2D RANS k-ε turbulence model and the rotating flow was captured using the moving reference frame method. Lift and drag were obtained for different angle of attacks via a control volume analysis of CFD results. …”
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Luteolin escape mutants of dengue virus map to prM and NS2B and reveal viral plasticity during maturation by Vasudevan, Subhash G., Peng, Minhua, Swarbrick, Crystall Marie Dawn, Chan, Kitti Wing-Ki, Luo, Dahai, Zhang, Wei, Lai, Xiaoping, Li, Geng

“…Time of drug addition assay with luteolin showed that the mutant viruses were able to produce more mature virions than WT in the order DM > SM2>SM1>WT. …”
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Reframing reflexivity: collaborative ethics, collective responsibility, and learnings from researching Russia’s war on Ukraine by Howlett, M, Kurylo, B

“…This paper critically examines the role of reflexivity in the study of wars, conflicts, and authoritarianism, drawing on insights gained from researching Russia’s war against Ukraine. …”

Impact of BPL penalty functions and PSF models in PET/CT radial spatial resolution recovery by Si, Wang Jie

“…Tubes filled were placed at 5 cm intervals from the center towards the PET/CT FOV's periphery. …”
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Improving access to pulmonary rehabilitation for patients with COPD treated for substance misuse in the London Borough of Islington by Narasimhan, Divya, Simpson, Jane, Stewart, Duncan

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Barriers and leverage points for seeing alcohol differently in integrated care systems in England: a senior stakeholder interview study by Madden, Mary, Stewart, Duncan, McCambridge, Jim

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Cortical regulation of sleep by Krone, LB

“…These experiments revealed unexpected effects of the chemogenetic actuators clozapine-N-oxide (CNO) and Compound 21 (Cmpd21) on sleep in wild type mice, which do not express designer receptors exclusively activated by designer drugs (DREADDs). …”

Investigation of Synthetic Proteins Produced via Automated Fast-Flow Peptide Synthesis by Cowfer, Amanda Elizabeth

“…I will discuss the iterative steps my team took to vary both chemical and mechanical and control variables to improve per-coupling yield enough to enable access to full-length single-domain proteins. On this journey, we utilized test peptides to validate synthesis quality and later synthesized a suite of full-length single-domain biologically active proteins. …”
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Biomolecular hydration in protein-protein interaction, protein stability and aggregation and lead optimization : computational studies by Mohan Rajan Pradhan

“…During the process of drug discovery, the question of which waters that exist in a binding site need to be displaced by the designed ligand is of critical importance and as yet has no universal solution. …”
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Investigating the content and function of stress-induced extracellular vesicles in colorectal cancer by Mason, J

“…Furthermore, switched EVs isolated from HCT116 cells (KRAS mutant) promote AREG-dependent resistance to EGFR monoclonal antibody therapy in Caco-2 (KRAS wild-type) cells. I also showed that switched EVs acted in an AREG-independent fashion to reduce tumour cell migration and invasion, potentially reflecting the mesenchymal-to-epithelial transition at distant sites during CRC metastasis.…”

Development and Application of a Data-Driven Signal Detection Method for Surveillance of Adverse Event Variability Across Manufacturing Lots of Biologics by Wilde, Joshua T., Springs, Stacy, Wolfrum, Jacqueline M., Levi, Retsef

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Loss of caveolin-1 impairs light flicker-induced neurovascular coupling at the optic nerve head by Loo, Jing Hong, Lee, Ying Shi, Woon, Chang Yi, Yong, Victor H. K., Tan, Bingyao, Schmetterer, Leopold, Chong, Rachel S.

“…Current treatment for glaucoma relies heavily on IOP-lowering drugs, however, there is an immense potential for new therapeutic strategies that increase Cav-1 expression or augment its downstream signaling in order to avert vascular dysfunction and glaucomatous change.…”
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Market outlook of VLCCs in the next 5 years by Cheah, Peifang.

“…The report shall focus on analyzing the demand and supply factors and subsequently draw a conclusion based on their effect on the freight rates. …”
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Label-free quantitative measurement of cardiovascular dynamics in a zebrafish embryo using frequency-comb-referenced-quantitative phase imaging by Boonruangkan, Jeeranan, Farrokhi, Hamid, Rohith, Thazhe Madam, Kwok, Samuel, Carney, Tom J., Su, Pei-Chen, Kim, Young-Jin

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