Tumor cell-intrinsic signals promoting tolerance and adaptation to oncogenic kinase inhibition by Flower, Cameron Timothy

“…By leveraging targeted and untargeted mass spectrometry (MS) of endogenous tyrosine-phosphorylated proteins, which enables phosphosite-specific quantification of TK signaling networks, I report several cell line-specific vulnerabilities not predicted to exist at the genetic level, and the consensus observation that sustained activity of SRC family kinases (SFKs), or of the SRC-like kinases ABL1/2, is an important contributor to GM-TKI tolerance in all lines. …”
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Fluid-fluid displacement in porous-media microfluidics by Qiu, Yu

“…Many questions remain, however, regarding how the macroscopic displacement patterns are controlled by the microscale interactions between the fluid interface and the solid surface in systems under geometric confinement like microfluidic devices and porous media. This fluid-solid interaction—exacerbated by the roughness inherent to all natural and engineered surfaces—introduces a large energy dissipation near the solid boundary that challenges our ability to interpret laboratory experiments and develop mathematical models. …”
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Smart window for tuning transparency and noise absorption by Shrestha, Milan

“…As a tunable optical surface scatter, it turns transparent with a smooth surface like a flat glass; but it turns ‘opaque’ (translucent) with the micro-rough surface. …”
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An NKX2-1GFP and TP63tdTomato dual fluorescent reporter for the investigation of human lung basal cell biology by Goh, Kim Jee, Tan, Ee Kim, Lu, Hao, Roy, Sudipto, Dunn, Norris Ray

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Functional metagenomic analysis of quorum sensing signaling in a nitrifying community by Tan, Chuan Hao, Yeo, Yee Phan, Muhammad Hafiz Ismail, Ng, Noele Kai Jing, Subramoni, Sujatha, Taj, Shireen, Tay, Martin, Chao, Xie, Kjelleberg, Staffan, Rice, Scott A.

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Cryogelation of human hair keratins by Chua, Huei Min

“…Microarchitecture analysis revealed that FT cycling rendered a change from sheet-like lamellae in FT0 sponges to interconnected polygonal pores in freeze-thawed sponges. …”
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Free-electron crystals for enhanced X-ray radiation by Wong, Wesley Lee Wei, Shi, Xihang, Karnieli, Aviv, Lim, Jeremy, Kumar, Suraj, Carbajo, Sergio, Kaminer, Ido, Wong, Liang Jie

“…Our work highlights an unprecedented regime of free electron light emission where electron waveshaping provides multi-dimensional control over practical radiation processes like bremsstrahlung. Our results pave the way towards greater versatility in table-top X-ray sources and improved fundamental understanding of quantum electron-light interactions.…”
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The stalks of the motor A1A0 ATP synthase come into the focus : structural insight into subunits E, F and H by Gayen, Shovanlal

“…The protein is dimeric and has a boomerang-like shape, composed of two arms of 12.0 and 6.8 nm in length. …”
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Photo-driven smart polymers and their molecular self-assembly by Hu, Jinhua

“…The synthesized azo-PEG polymers are lipid-like azobenzene-containing molecules. The simplistic and representative design of the azo-PEGs enables the in-depth studies of the self-assembly mechanism. …”
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Design methodologies for complexity reduction of FIR filters by Faust, Mathias

“…With the advance in VLSI technology, FIR digital filter and other convolution like calculations can be implemented by dedicated hardware to address the needs for high throughput applications such as those in the communication system frontend. …”
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Synthesis and optical characterization of cadmium sulfide (CdS) single crystals for laser cooling effect by Zhang, Chiyuan

“…It’s an improvement and detailed explanation of what a device using CdS crystal to realize laser cooling looks like and how it works based on what we have got so far. …”
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Structural study of ribosome : 1) structural basis of EF-G in translocation. 2) molecular mechanism of ribosome-dependent toxin YoeB in mRNA cleavage by Chen, Yun

“…During bacterial protein synthesis, elongation factor G (EF-G) facilitates the forward movement of the tRNA–mRNA by one codon, which is coupled to the ratchet-like movement of the ribosome and triggered by EF-G–mediated GTP hydrolysis. …”
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Non-invasive nanosensor monitoring of mRNA expression for regenerative medicine application by Wiraja, Christian

“…Conventionally, such verification is achieved through end-point, population-based methods like polymerase chain reaction (PCR; for mRNA expression) or western blotting (for protein expression). …”
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Voice conversion with parallel/non-parallel data and synthetic speech detection by Tian, Xiaohai

“…The objective of voice conversion techniques is to convert a source speaker's voice so that it sounds like that of a target speaker. Voice conversion belongs to a popular area of personalized speech generation. …”
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Populism in foreign policy by Chryssogelos, Angelos

“…The “people” for whom populists speak in international affairs can very well transcend national borders, as evidenced, for example, in the foreign policies of Hugo Chavez and Mahmud Ahmadinejad, who aimed to represent transnational constituencies like the Global South, the Islamic world, the world poor, etc. …”
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Localized structural and bulk effects in hybrid organic-inoraginc perovskites by Wong, Walter Pei De

“…Additionally, a better understanding of the material’s structure – property relationship would be valuable to the respective material’s application, like photovoltaics or efficient lighting application which are of increasing importance towards sustainability efforts. …”
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Effects of noise exposure on occupational stress among palm oil mill workers in Malaysia by Roya, Latifi Naeini

“…The study was conducted at seven sections of five selected palm oil mills and 173 participants were invited through purposive sampling based on inclusive criteria. …”
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Development of human enterovirus 71 nano calcium phosphate adjuvanted candidate vaccine for parenteral and mucosal delivery by Saeed Ahmed, Mohamed Ibrahim

“…The animals were immunized with HEV71 vaccine formulation and blood samples were withdrawn at 0, 1, 3, 5 and 7 weeks post immunization, the last samples were collected two weeks after the last dose. …”
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GeSn alloys fabricated by modified sputtering deposition by Qian, Li

“…Most commercial and military optoelectronic devices are fabricated by direct band-gap group III-V compounds like GaAs, InSb, InAsSb, etc. Recently, group IV Ge1-xSnx alloy has been attracting great attention. …”
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Solution-processed lead halide perovskite single crystal scintillators by Xie, Aozhen

“…Heavy element Pb, low fabrication cost and relatively strong emission make some of perovskite scintillators (like (PEA)2PbBr4 and (BA)2PbBr4 in this thesis) potentially competitive in comparison to current commercial scintillators. …”
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