Characterising the metabolic functionality of the preterm neonatal gut microbiome prior to the onset of necrotising enterocolitis: a pilot study by Chapman, JA, Wroot, E, Brown, T, Beck, LC, Embleton, ND, Berrington, JE, Stewart, CJ

“…While gut microbiome compositions associated with NEC have been well studied, there is a lack of experimental work investigating microbiota functions and their associations with disease onset. …”

Personalised modelling of geographic movements in depression by Palmius, N

“…<p>It has been estimated that as many as 41% of individuals will experience depression at some point in their lives, a serious and debilitating mental illness. …”

Identifying falsified COVID-19 vaccines by analysing vaccine vial label and excipient profiles using MALDI-ToF mass spectrometry by Arman, BY, Clarke, R, Bharucha, T, Gomez Fernandez, L, Walsby-Tickle, J, Deats, M, Mosca, S, Lin, Q, Banerjee, S, Chunekar, S, Patil, K, Gairola, S, Dunachie, S, Merchant, H, Stokes, R, Kuwana, R, Maes, A, Charrier, J-P, Probert, F, Caillet, C, Matousek, P, McCullagh, J, Newton, P, Zitzmann, N, Gangadharan, B

“…However, these developments are associated with the risk of a surge of substandard and falsified (SF) vaccines, as illustrated by the 184 incidents with SF and diverted COVID-19 vaccines which have been reported during the pandemic in 48 countries, with a paucity of methods for their detection in supply chains. …”

Mobile health (mHealth) interventions for health promotion during the perinatal period in India: a scoping review by Small, Z, Thompson, SE, Sharma, A, Majumdar, S, Thout, SR, Praveen, D, Hirst, JE

“…Many mobile health (mHealth) interventions have been developed to improve maternal and infant health outcomes in India, however it is unclear how mHealth can best support women in this culturally and resource diverse setting. …”

An aerodynamic investigation of a high-pressure turbine using rotor casing static pressure measurements at engine representative conditions with different tip designs, tip gaps and... by Singh, D, Beard, PF, Cardwell, D, Staelens, V, Bahulekar, P, Stokes, M, Bather, S, Chana, KS

“…Since the 1970s, extensive research has been undertaken to understand the over-tip leakage flow, and develop mitigation strategies such as novel tip designs, to minimize the losses and heat load. …”

Combined electron imaging and diffraction methods for understanding disordered rocksalt cathodes by Hedley, E

“…The nature of short range order (SRO) has been identified as a determining factor in the lithium migration properties, yet very few in-depth studies exist in the literature. …”

Study protocol for a pragmatic randomised controlled trial of comparing enhanced acceptance and commitment therapy plus (+) added to usual aftercare versus usual aftercare only, in... by Khan, I, Taylor, SJC, Robinson, C, Moschopoulou, E, McCrone, P, Bourke, L, Thaha, M, Bhui, K, Rosario, D, Ridge, D, Donovan, S, Korszun, A, Little, P, Morgan, A, Quentin, O, Roylance, R, White, P, Chalder, T

“…Discussion: To date, there have been no robust trials reporting both clinical and cost-effectiveness of an ACT based intervention for people with low QoL after curative cancer treatment in the UK. …”

Malaria as a cause of morbidity and mortality in children with homozygous sickle cell disease on the coast of Kenya by Komba, A, Makani, J, Sadarangani, M, Ajala-Agbo, T, Berkley, J, Newton, CRJC, Marsh, K, Williams, T

“…<p><strong>Background</p></strong>To date, it has been widely assumed that malaria is a common cause of morbidity and mortality in children with sickle cell disease (SCD) in malaria-endemic countries, and as a result, malarial prophylaxis is commonly recommended. …”

The development of electrochemical sensors based on the use of different forms of carbon materials by Chaisiwamongkhol, K

“…</p> <p>In this thesis, carbon based materials such as pyrolytic graphite; carbon nanotubes and carbon fibre have been used for a number of analytical and fundamental investigations. …”

Self-harm-related mental imagery: a content analysis study of imagery reported by young people referred to mental health services by Susi, K, Stewart, A, Knowles Bevis, R, Hawton, K

“…<p><strong>Background: </p></strong>Growing evidence suggests that self-harm-related mental imagery is involved in the transition from self-harm ideation to enactment. However, there has been little research on this important phenomenon in adolescent populations. …”

Mitigating marine megafauna captures in fisheries by Arlidge, W

“…Yet to date, the exploration of the biodiversity mitigation process to the primary resource sectors has not been widely investigated as a subject of study in conservation. …”

Citizenship and the politics of poverty definition during the segregation, apartheid and democratic eras in South Africa: 1910-2010 by Magasela, W

“…</p> <p>In the post-apartheid era with a Constitution that enshrines a Bill of Rights with explicit and specific social and economic rights, and human dignity, social justice and the commitment to improve the quality of life of all citizens as foundational values aimed at addressing extensive multi-dimensional poverty, apartheid era concepts and definitions of poverty (mainly the HSL and MLL) continue. This has been reinforced by the analyses of poverty undertaken by the World Bank in the post-apartheid era. …”

Respiratory quality indices for automated monitoring of respiration from sensor data by Birrenkott, D

“…This is primarily because of the lack of a non-invasive, robust, automated method for estimating RR. It has previously been shown that the amplitude modulation (AM), frequency modulation (FM), and baseline wander (BW) of both the electrocardiogram (ECG) and photoplethysmogram (PPG) contain respiratory waveform information. …”

18F-labelling of new chemotypes for drug discovery by Khotavivattana, T

“…</p> <p>The Umemoto reagent has been extensively used for electrophilic trifluoromethylation of various functional groups. …”

BCC metals in extreme environments: modelling the structure and evolution of defects by Gilbert, M

“…Additionally, we compare the diffusion rates of these vacancy loops to their interstitial counterparts and find that, while interstitial loops are more mobile, the difference in mobility is not as significant as might have been expected. In part II we study screw dislocations, which, as the rate limiting carriers of plastic deformation, are significantly responsible for the strength of materials. …”

Cost-utility analysis of molnupiravir plus usual care versus usual care alone as early treatment for community-based adults with COVID-19 and increased risk of adverse outcomes in... by Png, ME, Harris, V, Grabey, J, Hart, ND, Jani, BD, Butler, D, Carson-Stevens, A, Coates, M, Cureton, L, Dobson, M, Dorward, J, Evans, P, Francis, N, Gbinigie, OA, Hayward, G, Holmes, J, Hood, K, Khoo, S, Ahmed, H, Lown, M, McKenna, M, Mort, S, Nguyen-Van-Tam, J, Rahman, N, Richards, DB, Thomas, N, van Hecke, O, Hobbs, FR, Little, P, Yu, L-M, Butler, CC, Petrou, S

“…<p><strong>Background </p></strong>The cost-effectiveness of molnupiravir, an oral antiviral for early treatment of SARS-CoV-2, has not been established in vaccinated populations. <p><strong> Aim </p></strong>To evaluate the cost-effectiveness of molnupiravir relative to usual care alone among mainly vaccinated community-based people at higher risk of severe outcomes from COVID-19 over 6 months. …”

Individual differences in the effects of physical activity on classroom behaviour by Heemskerk, CHHM, Sumatic, M, Strand, S, Malmberg, L-E

“…Increasing children’s on-task behaviour is of particular importance to teachers, and while it has previously been suggested that PA can improve classroom behaviour, a consensus on the dose-response relationship of PA content, and its interaction with children’s individual differences, is yet to be reached. …”

Qualitative evaluation of the implementation and national roll-out of the NHS App in England by Reidy, C, Papoutsi, C, KC, S, Gudgin, B, Laverty, AA, Greaves, F, Powell, J

“…Similar patient portals have been adopted in different formats and with variable levels of success. …”

A multi-omics strategy to understand PASC through the RECOVER cohorts: a paradigm for a systems biology approach to the study of chronic conditions by Sun, J, Aikawa, M, Ashktorab, H, Beckmann, ND, Enger, ML, Espinosa, JM, Gai, X, Horne, BD, Keim, P, Lasky-Su, J, Letts, R, Maier, CL, Mandal, M, Nichols, L, Roan, NR, Russell, MW, Rutter, J, Saade, GR, Sharma, K, Shiau, S, Thibodeau, SN, Yang, S, Miele, L, NIH Researching COVID to Enhance Recovery (RECOVER) Consortium

“…Many of our recommendations have already been considered by the NIH through the peer-review process, resulting in the creation of a systems biology panel that is currently designing the studies we proposed. …”

The impact of natural climate variability on the global distribution of Aedes aegypti: a mathematical modelling study by Kaye, AR, Obolski, U, Sun, L, Hart, WS, Hurrell, JW, Tildesley, MJ, Thompson, RN

“…However, the role of natural climate variability in modifying the effects of anthropogenic climate change on future environmental suitability for Ae aegypti has not been assessed fully. In this study, we aim to assess uncertainty arising from natural climate variability in projections of Ae aegypti suitability up to the year 2100. …”