Seizure amelioration effect of omega-3 EPA and DHA fatty acid supplementation on patients with drug resistant epilepsy: a scoping review using the GOED clinical study database by Abuknesha, Nada R., Searle, Andrew J.

“…A supplementation period of 3 months or less was employed by 72.7% of RCTs. 54.5% of RCTs reported a positive outcome of at least 50% or more significant reduction in seizure frequency compared to placebo or baseline. 27.2% of RCTs reported significant seizure freedom in patients during or at the end of the supplementation period, compared to placebo. …”
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Determinants of underdiagnosis of COPD in national and international surveys by Lamprecht, B, Soriano, JB, Studnicka, M, Kaiser, B, Vanfleteren, LE, Gnatiuc, L, Burney, P, Miravitlles, M, García-Rio, F, Akbari, K, Ancochea, J, Menezes, AM, Perez-Padilla, R, Montes de Oca, M, Torres-Duque, CA, Caballero, A, González-García, M, Buist, S

“…Only 26.4% reported a previous lung function test, and only 5.0% reported a previous diagnosis of COPD, whereas 9.7% had a postbronchodilator FEV1/FVC < LLN. …”

The relationship between viral clearance rates and disease progression in early symptomatic COVID-19: a systematic review and meta-regression analysis by Singh, S, Boyd, S, Schilling, WHK, Watson, JA, Mukaka, M, White, NJ

“…Treatment benefit was defined clinically as the relative risk of hospitalization/death during follow-up (≥14 days), and virologically as the SARS-CoV-2 viral clearance rate ratio (VCRR). The VCRR is the ratio of viral clearance rates between the intervention and control arms. …”

A comparative analysis of vitrification and two slow freezing methods for gonocyte-containing neonatal calf testicular tissue and subsequent in vitro culture by Tang, S, Jones, C, Davies, J, Lane, S, Coward, K

“…No significant differences were observed in the proportion of seminiferous tubules containing PGP9.5-positive germ cells when compared between the three methods. …”

Relapse after cessation of weekly tocilizumab for giant cell arteritis: a multicentre service evaluation in England by Quick, V, Abusalameh, M, Ahmed, S, Alkoky, H, Bukhari, M, Carter, S, Coath, FL, Davidson, B, Doddamani, P, Dubey, S, Ducker, G, Griffiths, B, Gullick, N, Heaney, J, Holloway, A, Htut, EEP, Hughes, M, Irvine, H, Kinder, A, Kurshid, A, Lim, J, Ludwig, DR, Malik, M, Mercer, L, Mulhearn, B, Nair, JR, Patel, R, Robson, J, Saha, P, Tansley, S, TOC STOP 2022 Investigators, Mackie, SL

“…At time of stopping qwTCZ, median (IQR) prednisolone dose was 2 (0–5) mg/day. By 6, 12 and 24 months after stopping qwTCZ, 21.4%, 35.4% and 48.6%, respectively, had relapsed, requiring an increase in prednisolone dose to a median (IQR) of 20 (10–40) mg/day. 33.6% relapsers had a major relapse as defined by EULAR. …”

Reallocation of time between device-measured movement behaviours and risk of incident cardiovascular disease by Walmsley, R, Chan, S, Smith-Byrne, K, Ramakrishnan, R, Woodward, M, Rahimi, K, Dwyer, T, Bennett, D, Doherty, A

“…For an average individual, reallocating 20 min/day to MVPA from all other behaviours proportionally was associated with 9% (95% CI 7% to 10%) lower risk, while reallocating 1 hour/day to sedentary behaviour from all other behaviours proportionally was associated with 5% (95% CI 3% to 7%) higher risk.</p> <p><strong>Conclusion</strong> Machine-learning methods classified movement behaviours accurately in free-living accelerometer data. …”

‘An unimaginable challenge’: a cross-cultural qualitative study of ethics and decision-making around tracheostomy ventilation in patients with amyotrophic lateral sclerosis by Ozeki-Hayashi, R, Wilkinson, D

“…<p><strong>Methods</strong></p> We conducted semi-structured in-depth interviews with 16 doctors actively involved in the management of ALS patients from Japan (n=7), the UK (n=5), and the US (n=4). We used three hypothetical cases to explore decision-making. …”

Understanding the consequences of education inequality on cardiovascular disease: mendelian randomisation study by Carter, AR, Gill, D, Davies, NM, Taylor, AE, Tillmann, T, Vaucher, J, Wootton, RE, Munafò, MR, Hemani, G, Malik, R, Seshadri, S, Woo, D, Burgess, S, Davey Smith, G, Holmes, MV, Tzoulaki, I, Howe, LD, Dehghan, A

“…All three risk factors combined were estimated to mediate 42% (36% to 48%) and 36% (5% to 68%) of the effect of education on coronary heart disease in observational and mendelian randomisation analyses, respectively. …”

Jamaican customs data, c. 1800-45 by Graham, A, Lavallee, E

“…Unless otherwise noted, years follow the financial year of the island, running from 30 September to 29 September i.e. "1824/5" refers to the period 30 September 1824 to 29 September 1825.…”

Sudden gains in internet cognitive therapy for social anxiety disorder in routine clinical practice by Yim, SH, Clark, DM, Salkovskis, PM, Thew, GR

“…</p> <p><strong>Conclusions:</strong>&nbsp;Approximately 2 in 5 patients experienced a sudden gain whilst accessing the iCT-SAD intervention in routine practice. …”

Targeting c-Met for endoscopic detection of dysplastic lesions within Barrett’s esophagus using EMI-137 fluorescence imaging by Huang, Y-J, Rieder, J, Tan, KV, Tenditnaya, A, Vojnovic, B, Gorpas, D, Quante, M, Vallis, KA

“…<p>Purpose: Esophageal cancer (EC) carries a poor prognosis with 5-year overall survival of less than 20%. Barrett&rsquo;s esophagus (BE) increases the risk of esophageal adenocarcinoma (EAC). …”

Predictors for severe persisting pain in rheumatoid arthritis are associated with pain origin and appraisal of pain by Baerwald, CG, Stemmler, E, Gnüchtel, S, Jeromin, K, Fritz, B, Bernateck, M, Adolf, D, Taylor, PC, Baron, R

“…</p> <br> <p><strong>Results:</strong> Of 567 patients, 337 (59.4%) were classified as reference group, 102 (18.0%) as nonresponders, and 128 (22.6%) as patients with persisting pain. 21 (8.8%) responders, 28 (35.0%) non-responders, and 27 (26.5%) persisting pain patients tested positive for NeP at week 24. …”

Cost-utility analysis of molnupiravir plus usual care versus usual care alone as early treatment for community-based adults with COVID-19 and increased risk of adverse outcomes in... by Png, ME, Harris, V, Grabey, J, Hart, ND, Jani, BD, Butler, D, Carson-Stevens, A, Coates, M, Cureton, L, Dobson, M, Dorward, J, Evans, P, Francis, N, Gbinigie, OA, Hayward, G, Holmes, J, Hood, K, Khoo, S, Ahmed, H, Lown, M, McKenna, M, Mort, S, Nguyen-Van-Tam, J, Rahman, N, Richards, DB, Thomas, N, van Hecke, O, Hobbs, FR, Little, P, Yu, L-M, Butler, CC, Petrou, S

“…<p><strong>Background </p></strong>The cost-effectiveness of molnupiravir, an oral antiviral for early treatment of SARS-CoV-2, has not been established in vaccinated populations. …”

Addition of macrolide antibiotics for hospital treatment of community-acquired pneumonia by Wei, J, Walker, S, Eyre, D

“…No evidence of difference was found in time to discharge from additional macrolides to amoxicillin (restricted mean days lost +1.76 [-1.66,+5.19]), or co-amoxiclav (+0.44 [-1.63,+2.51]). …”

Response of appetite and potential appetite regulators following intake of high energy nutritional supplements by Fatima, S, Gerasimidis, K, Wright, C, Tsiountsioura, M, Arvanitidou, E-I, Malkova, D

“…</p> <p><strong>Design</strong> Twenty three females of 24.4 ± 2.8 years with BMI of 18.2 ± 0.8 kg/m2 consumed HENSD (2.5 MJ) or PLACEBO (0.4 MJ) in fasted state in a single blind randomized cross-over study. …”

Pemencilan, pencirian dan afiliasi filogenetik endofit Streptomyces sp. bioaktif daripada pokok yang mempunyai nilai perubatan by Nurul ‘Izzah Mohd Sarmin, Noraziah Mohamad Zin

“…Berdasarkan analisis filogenetik jujukan gen 16S rRNA, semua pencilan dikelaskan sebagai Streptomyces eurythermus ATCC 14975T (persamaan jujukan gen 98.5%). Pencilan SUK 8, SUK 10 dan SUK 15 juga menunjukkan corak aktiviti biologi yang serupa yang berupaya merencat sehingga 100% organisma patogen yang sama. …”
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Microwave- and oven-heat moisture treatment of broken rice flour and the improvement in the flat rice noodle quality by Mustapha, Nor Afizah, Lai, Yan Tang, Wan Ibadullah, Wan Zunairah, Shukri, Radhiah

“…Rice flour adjusted to 20% moisture content was subjected to two HMT techniques; oven-heat moisture treatment (O-HMT) at 110°C for 3 h and microwave-heat moisture treatment (M-HMT) at 119 W for 5 min. HMT reduced the swelling capacity and solubility of the flour. …”
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Reproductive performance and physiological responses in Awassi ewes under intravaginal sponges application and fed Selenium and Vitamin E by Saeed, O.A., Ahmed, N.K., Taha, M.M., Abedal-Majed, M.A., Ali, F.M., Samsudin, A.A.

“…The experimental ewes were assigned into three groups; the control group (SE0) received 2 mL of sterile saline per head, the second group (SE1) received 1.5 mL/head Se and vitamin E (150 mg α-Tocopherol acetate + 0.15 mg Sodium selenite), while the third group (SE2) received 3 mL/head (150 mg α-Tocopherol acetate + 0.15 mg Sodium selenite). …”
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Optimization of extraction for efficient recovery of kenaf seed protein isolates: evaluation of physicochemical and techno-functional characteristics by Hamim, Nur Aqilah, Saari, Nazamid, Wan Ibadullah, Wan Zunairah, Mohamed, Abdul Manan Dos, Anwar, Farooq, Hasan, Muhamad Yusuf, Abdul Rahim, Mohd Zulkhairi, Abdul Rahman, Muhammad Sharir, Karim, Roselina

“…The key parameters affecting the yield and protein content were optimized, including extraction pH (2–11), seed:water ratio (5:1–50:1), temperature (30–90 °C), and duration (20–360 min). …”
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Association between breakfast consumption pattern with body mass index (bmi) and physical activity among undergraduate students in Universiti Sains Malaysia, Health Campus, Kubang... by Zulkifflee, Iwani Afifah

“…The majority of respondents were female (81.0%), aged between 19 and 23 years (90.5%) with a mean age of 21.90 ± 1.40 years. Most respondents were third-year students (32.8%), PPSK students (87.1%), and of Malay ethnicity (64.7%). …”
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