Studies towards the synthesis of bioactive natural products and development of new synthetic methods by Khanizeman, Rabi’ah Nisha

“…Therefore the content of this thesis describes the syntheses and development of new synthetic methods towards bioactive natural products containing 1,3-amino alcohol, 1,3-diamine, THP-ring as well as tri-aryl ethylene unit which represent the key themes of (+)-negamycin (Chapter 1), (-)-cernuine and (+)-cermizine D (Chapter 2), enigmazole A (Chapter 3) and tamoxifen (Chapter 4), respectively.…”
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Astley's Amphitheatre and the early circus in England, 1768-1830 by Kwint, M

“…<p>Founded in Lambeth in 1768 by the ex-cavalry sergeant Philip Astley (1742-1814), Astley's was one of the first entertainments to mix traditional acrobatic feats with the new trick-riding in a ring, thus founding the modern circus. As the leading example of the artform, the permanent Amphitheatre just south of Westminster Bridge went on to be immortalised by Dickens and parodied by Punch, before closure in 1893. …”

Evolved P450 mutants as general oxidation catalysts by Harwood, LA

“…Improvements to a previous synthetic route, two routes based on a C(sp²)–C(sp²) bond disconnection and a final route constructing the aryl ring via Robinson annulation will be discussed. New methodologies including an intramolecular Heck cross-coupling and a Lewis acid catalysed coupling of furfuryl alcohols with silyl enol ethers will be presented.…”

Structural insights into viral RNA capping and plasma membrane targeting by Chikungunya virus nonstructural protein 1 by Zhang, Kuo, Law, Yee-Song, Law, Michelle Cheok Yien, Tan, Yaw Bia, Wirawan, Melissa, Luo, Dahai

“…Twelve copies of nsP1 form a crown-shaped ring structure with a 7.5-nm-wide channel for mediating communication and exchange between the viral RC and the host cell. …”
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Synthesis of some selenacrown ethers and the thermodynamic origin of their complexation with C60 by Liu, Yu, Han, Jian Rong, Zhao, Yanli, Zhang, Heng Yi, Duan, Zhong Yu

“…The obtained Ks values together with that reported for dicyclohexano-24-crown-8 (5) reveal that, the more the heteroatom numbers in crown ether ring are, and the larger the cavity sizes of crown ethers are, the higher the Ks values for complexation with C60 are. …”
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Benzofuran-based estrogen receptor α modulators as anti-cancer therapeutics : in silico and experimental studies by Leow, Min Li, Chin, Christina Hui Li, Yu, Peggy Shuang, Pasunooti, Kalyan Kumar, Tay, Raymond Xu Zhan, Zhang, Dawei, Yoon, Ho Sup, Liu, Xue-Wei

“…From the SAR studies, potential functional groups have been identified, the two hydroxyl groups at C-5 and C-6 and the phenyl ring at C-2, which showed considerable cytotoxicity in MCF-7 breast cancer cells. …”
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Search of the early O3 LIGO data for continuous gravitational waves from the Cassiopeia A and Vela Jr. supernova remnants by Sudhir, Vivishek

“…We carry out the searches in the LIGO data from the first six months of the third Advanced LIGO and Virgo observing run, using the Weave semi-coherent method, which sums matched-filter detection-statistic values over many time segments spanning the observation period. No gravitational wave signal is detected in the search band of 20--976 Hz for assumed source ages greater than 300 years for Cas A and greater than 700 years for Vela Jr. …”
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Designing a brain-computer interface platform for attention training by B Thirukarthik

“…In this study, we will be looking into a new platform to aid in training the attention span of the regular persons. This platform is a game application designed in Unity Engine and uses the Muse2 device as a BCI and the Tobii Eye Tracker as input method to control the player and complete minor objectives. …”
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Spatial-temporal sensor data imputation in traffic data modelling by Nie, Helei

“…The results show that RBF approach is capable of imputing missing values, especially in a short missing span. By incorporating the available dimensions of the data, RBF method can utilize the information from time and space dimensions for effective imputation with higher missing ratios. …”
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Theoretical models for performance analysis of spintronic THz emitters by Yang, Yingshu, Dal Forno, Stefano, Battiato, Marco

“…The terahertz (THz) region of the electromagnetic spectrum, spanning from 0.1 to 10 THz, offers unique opportunities for imaging, spectroscopy, and communication applications. …”
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Truss-arch model for shear strength of shear-critical reinforced concrete columns by Pan, Zuanfeng., Li, Bing.

“…Significant arch action is found in columns of small shear span-to-depth ratio and high axial-load ratio under shear force. …”
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Resilience of power distribution systems by Ng, Si Qi

“…A modified 33-bus test system is verified with six faults and three types of consumers (industrial, commercial and residential) in a reasonable time span. The results obtained showed how consumers are less likely to be affected by disruptions when distributed generators are present. …”
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CFD investigation of a distributed propulsion system by Chng, Jia Yang

“…A distributed propulsion system uses a series of engines distributed span-wise across the aircraft’s wing with the aim to increase aircraft performance. …”
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Risk management framework for construction project managers by Tan, Ying Ling

“…With an emphasis on process-driven projects, the research identifies the critical need for an integrated approach to risk management, spanning from project initiation through to operational and maintenance phases. …”
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Finding meaning behind immortality of Anne Rice’s vampires. by Nurhayati Zakaria.

“…Immortality plays a central role in the continuous inquiry into the vampires’ nature and existence throughout the span of many centuries. These novels follow the psychological and emotional experiences of vampiric immortality, firstly, via two first-person accounts of two separate vampires, Louis and Lestat, and later trace Rice’s interpretation of vampiric urban legend through the stories of various vampires of different walks of life. …”
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Behaviour of precast concrete joints subject to a missing column scenerio by Wee Jun Yang.

“…The sub-assemblages include two-span beams with two column stubs and a middle beam-column joint. …”
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Micropipette aspiration of a living cell by Badjo, Wenna

“…Using the viscoelastic model, it was found that PDMS 20:1 will result in higher stiffness of cell and the longer the cell is cultured on the substrate, the stiffer the cell, however this is only apply for the span of 7 days. On the other hand, no substantiate conclusion is drawn from the elastic modulus. …”
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Effect of a circular tunnel in the foundation soil on the seismic response of dikes by Yeong, Siang Phong

“…A dry sand dike of 12 m crest span, 60 m base width and 8 m height is selected as the model in this study. …”
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Futurism: performance and performativity of a movement by Scarso, Jacek Ludwig

“…Performance interventions span across the history of this movement (Goldberg, 2011): from the notorious 'serate' instigated by Marinetti, in which the audience would be purposefully scandalised, provoked and offended, to the futurist music concerts that provided an ancestral root for the aesthetics of synthesised sound in contemporary music (Rodney, 1976), not to mention the Russian counterpart of this movement, which embraced, on stage, such wide a field as to encompass theatre, opera, dance, music and scenic design. …”
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Warming alters plankton body-size distributions in a large field experiment by Albini, D, Ransome, E, Dumbrell, AJ, Pawar, S, O’Gorman, EJ, Smith, TP, Bell, T, Jackson, MC, Woodward, G

“…While substantial empirical evidence has accumulated in recent years on such changes, we still lack general insights due to a limited coverage of warming scenarios that span spatial and temporal scales of relevance to natural systems. …”