Self-Nanoemulsifying Drug Delivery System (SNEDDS) formulation and molecular docking of mahogany seed extract (Swietenia mahagoni) as anti-hyperglycemic by Mushawwir Taiyeb, Mushawwir Taiyeb, Hartati Hartati, Hartati Hartati, Arwansyah Arwansyah, Arwansyah Arwansyah, Dahlia, Dahlia, Abd. Muis, Abd. Muis, A. Mu'nisa, A. Mu'nisa, Arif, Abdur Rahman, Md. Salleh, Liza

“…So, research was carried out to determine the formulation and optimization of nanoemulsion from mahogany seed extract (Swietenia mahagoni) and its effect on reducing blood glucose levels in mice (Mus musculus L.). Based on research that has been carried out, the nanoemulsion formula for mahogany seed extract is characterized by a transmittance percentage of 84.7 % and a particle size of 12.21 nm. …”
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Roseburia intestinalis generated butyrate boosts anti-PD-1 efficacy in colorectal cancer by activating cytotoxic CD8⁺ T cells by Kang, Xing, Liu, Changan, Ding, Yanqiang, Ni, Yunbi, Ji, Fenfen, Lau, Harry Cheuk Hay, Jiang, Lanping, Sung, Joseph Jao Yiu, Wong, Sunny Hei, Yu, Jun

“…R. intestinalis administration significantly inhibited tumour formation in Apc(Min/+) mice, which was confirmed in mice with AOM-induced CRC. …”
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Finite element analysis on post-buckling of thin-walled structures using ANSYS by Theint, Yi Mon

“…The results obtained were checked against experimental data and led to the development and the revision of design procedures for the pin-ended lipped column and hollow box section.…”
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Driving mechanism development for autonomous hospital bed by Tan, Jia Liang

“…Demand is foreseen to spike and a range of healthcare services that range from acute to community care is necessary for a holistic healthcare system. …”
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Efficient position decoding methods based on fluorescence calcium imaging in the mouse hippocampus by Tu, Mengyu, Zhao, Ruohe, Adler, Avital, Gan, Wen-Biao, Chen, Zhe S.

“…Here, we develop an efficient strategy to extract features from fluorescence calcium imaging traces and further decode the animal's position. We validate our spike inference-free decoding methods in multiple in vivo calcium imaging recordings of the mouse hippocampus based on both supervised and unsupervised decoding analyses. …”
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Electrolyte-gated neuromorphic transistors for brain-like dynamic computing by He, Yongli, Jiang, Shanshan, Chen, Chunsheng, Wan, Changjin, Shi, Yi, Wan, Qing

“…Particularly, dynamics play an essential role in neural spike information processing. Here, we offer a brief review and perspective in the field of electrolyte-gated neuromorphic transistors for brain-like dynamic computing. …”
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Clustering of designers based on building information modeling event logs by Pan, Yue, Zhang, Limao, Skibniewski, Miroslaw J.

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Dual attention deep learning network for automatic steel surface defect segmentation by Pan, Yue, Zhang, Limao

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The inference-boundary model reinterpreting theme and rheme by Leong, Ping Alvin

“…The Hallidayan notions of theme and rheme pose an interesting challenge to linguists in their attempts to pin them down more specifically. This paper argues that since the thematic structure of the clause organises it as a message, a useful starting point in theme–rheme research is an understanding of how clausal messages are typically processed by language users. …”
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Policy complexity suppresses dopamine responses by Gershman, SJ, Lak, A

“…We show that male and female mice achieve performance on a perceptual decision task that is near-optimal given their capacity limits, as measured by policy complexity (the mutual information between states and actions). …”

Design and Implementation of Active Antennas for IoT-Based Healthcare Monitoring System by MUSA, UMAR, MOHD SHAH, SHAHARIL, A. MAJID, HUDA, AHMAD MAHADI, ISMAIL, A. RAHIM, MOHAMAD KAMAL, YAHYA, MUHAMMAD SANI, ZAINAL ABIDIN, ZUHAIRIAH

“…Two dual-band (2.4 GHz and 5.8 GHz) microstrip patch antennas, one with a PIN diode and one without, are fabricated using Rogers Duroid RO3003™ substrate. …”
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Design and Implementation of Active Antennas for IoT-Based Healthcare Monitoring System by MUSA, UMAR, MOHD SHAH, SHAHARIL, A. MAJID, HUDA, MAHADI, ISMAIL AHMAD, A. RAHIM, MOHAMAD KAMAL, YAHYA, MUHAMMAD SANI, ZAINAL ABIDIN, ZUHAIRIAH

“…Two dual-band (2.4 GHz and 5.8 GHz) microstrip patch antennas, one with a PIN diode and one without, are fabricated using Rogers Duroid RO3003™ substrate. …”
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Evaluation of population immunity against SARS-CoV-2 variants, EG.5.1, FY.4, BA.2.86, JN.1, JN.1.4, and KP.3.1.1 using samples from two health demographic surveillance systems in K... by Lugano, D, Kutima, B, Kimani, M, Sigilai, A, Gitonga, J, Karani, A, Akech, D, Karia, B, Ziraba, AK, Maina, A, Lambisia, A, Omuoyo, D, Mugo, D, Lucinde, R, Owuor, S, Konyino, G, Newman, J, Bailey, D, Nduati, E, Githinji, G, Agoti, CN, Bejon, P, Scott, JAG, Agweyu, A, Warimwe, GM

“…The majority of these mutations mainly target the spike protein, allowing the new variants to escape the immunity previously raised by vaccination and/or infection by earlier variants of SARS-CoV-2. …”

An immunoinformatic approach for identifying and designing conserved multi-epitope vaccines for coronaviruses by Ong, Yu Chuan, Tejo, Bimo Ario, Yap, Wei Boon

“…Methods: This study utilized an immunoinformatic approach to identify evolutionarily conserved CD4+ (HTL) and CD8+ (CTL) T cells, and B-cell epitopes in the coronaviral spike (S) glycoprotein. Results: A total of 132 epitopes were identified, with the majority of them found to be conserved across the bat CoVs, pangolin CoVs, endemic coronaviruses, SARS-CoV-2, and Middle East respiratory syndrome coronavirus (MERS-CoV). …”
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Banks regulatory reforms in Singapore. by Foo, Cindy Ping Ping., Lee, Shirleen Sok Loon., Ng, Mui Chee.

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Dysregulation of the Pdx1/Ovol2/Zeb2 axis in dedifferentiated β-cells triggers the induction of genes associated with epithelial-mesenchymal transition in diabetes by de Jesus, Daniel S., Mak, Tracy C. S., Wang, Yi-Fang, von Ohlen, Yorrick, Bai, Ying, Kane, Eva, Chabosseau, Pauline, Chahrour, Catherine M., Distaso, Walter, Salem, Victoria, Tomas, Alejandra, Stoffel, Markus, Rutter, Guy A., Latreille, Mathieu

“…We usedb-cell-specific miR-7 overexpressing mice (Tg7) to testthe hypothesis that loss ofb-cell identity triggered by miR-7 overexpression alters islet gene expression and islet microenvironment in diabetes.Methods:We performed bulk and single-cell RNA sequencing (RNA-seq) in islets obtained fromb-cell-specific miR-7 overexpressing mice(Tg7). …”
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Renal-clearable molecular probe for near-infrared fluorescence imaging and urinalysis of SARS-CoV-2 by Liew, Si Si, Zeng, Ziling, Cheng, Penghui, He, Shasha, Zhang, Chi, Pu, Kanyi

“…Such a design not only allows sensitive detection of Mpro in the lungs of living mice after intratracheal administration but also permits optical urinalysis of SARS-CoV-2 infection. …”
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Dose escalation pre-clinical trial of novel DOK7-AAV in mouse model of DOK7 congenital myasthenia by Cossins, J, Kozma, I, Canzonetta, C, Hawkins, A, Beeson, D, Sepulveda, P, Dong, YY

“…EMG showed that the treated model mice had decrement of compound muscle action potential on repetitive nerve stimulation, which indicates defective signalling at the neuromuscular junction. …”

Unraveling the Dynamics of Mental and Visuospatial Workload in Virtual Reality Environments by Bernal, Guillermo, Jung, Hahrin, Yassı, İsmail Emir, Hidalgo, Nelson, Alemu, Yodahe, Barnes-Diana, Tyler, Maes, Pattie

“…Our findings indicate a broadband increase in EEG power just prior to a helper event, followed by a spike of visuospatial engagement (parietal alpha and beta 0-1-3 s) occurring concurrently with a decrease in mental workload (frontal theta 2–4 s), and subsequent decreases in visuospatial engagement (parietal theta at 14 s) and physiological arousal (HRV at 20 s). …”
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Analysis and reduction of mismatch in silicon neurons by Shuo, Sun, Basu, Arindam

“…The method presented allows the corrected neurons to compute both rate codes and spike time codes in a mismatch resilient fashion…”
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