Nuclei sorting-based genome-wide CRISPR screens to identify novel regulators of hepatic insulin signalling by Martin Perez, E

“…To systematically study the insulin signalling network, we developed and validated a novel experimental pipeline that uses nuclei isolation followed by fluorescent activated nuclei sorting (FANS) as an approach for pooled CRISPR screening. We carried out nine genome-wide pooled CRISPR screens using nuclei isolated from hepatocytes under either starved, basal insulin or insulin resistance conditions. …”

Use of hormone replacement therapy and risk of breast cancer: nested case-control studies using the QResearch and CPRD databases by Vinogradova, Y, Coupland, C, Hippisley-Cox, J

“…In recent oestrogen only users, between three (in younger women) and eight (in older women) extra cases per 10 000 women years would be expected, and in oestrogen-progestogen users between nine and 36 extra cases per 10 000 women years. For past oestrogen-progestogen users, the results would suggest between two and eight extra cases per 10 000 women years. …”

In-silico trials with human modelling and simulation for guiding optimal stratification of atrial fibrillation patients to catheter ablation and pharmacological therapy by Dasí i Martinez, A

“…</p> <br> <p>Moreover, the ionic current substrate also influences the outcomes of catheter ablation therapy, although the latter is mainly determined by the presence of heterogeneities in tissue structure (i.e., presence of low voltage areas) and the bi-atrial size (i.e., left and right atrial volume). In fact, analysis of nine state-of-the-art catheter ablation strategies suggests that the assessment of the latter patient characteristics could guide stratification of AF patients to optimal ablation therapies.…”

Knowledge, beliefs, perceptions and barriers related to implementing smoke-free home practices in two rural settlement areas in Malaysia by Kamni, Siti Nurhasyimah Ayuni, Saiful Bahron, Nur Ain Nadhirah, Zulkifli, Aziemah, Uny, Isabelle, O’Donnell, Rachel, Prabandari, Yayi Suryo, Bintoro, Bagas Suryo, Zainal Abidin, Emilia, Semple, Sean

“…No association was found between sociodemographic factors and knowledge level. Seven of the nine interviewees knew specific SHS-related health risks. …”
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Evaluation of high school-based dengue solution model in Southern Thailand: a community participatory action research by Suwanbamrung, Charuai, Mehraj, Sandeep Kumar, Kercho, Melkamu Worku, Stanikzai, Muhammad Haroon, Ageru, Temesgen Anjulo, Jaroenpool, Jiraporn, Pibul, Panatda, Shohaimi, Shamarina, Israel, Eskinder

“…Results: Two hundred and thirty-nine (96.3%, n = 239/248) and 232 (93.5, n = 232/248) participants were included in the interventions before and after, respectively. …”
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Control and operation of DC microgrids by Adhikari, Sujan

“…The interconnection of identical DC buses through tie-line and formation of microgrid clusters improves reliability of the system. …”
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Design of a voltage collapse monitoring device using local information by Myo Oo, Myint Thein.

“…The result will show as line graph on the display window of MATLAB developed program in real-time. …”
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Political economy of Malaysia's vision 2020. by Chin, Kiang Mun.

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Proteomics and metabolomics analysis of cellular responses to β-blocker carvedilol by Wang, Mingxuan

“…Consequently, developing robust cell line-based proteomics and metabolomics platforms will greatly facilitate understanding of drug-cell interactions.…”
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The Central Provident Fund investment schemes by Choo Wei Kiat, Chua Meng Chee, Toh Hai Joo

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Data visualization and analysis for WiFi-based occupancy detection in smart homes by Pan, Xingmeng

“…The final output is a web page containing multi-line charts that contain visualized real-time data coming from the WiFi system and the analysis result which shows the occupancy status of the room. …”
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Discriminative learned dictionaries for local image analysis by Mairal, J, Bach, F, Ponce, J, Sapiro, G, Zisserman, A

“…This article extends this line of research into a novel framework for local image discrimination tasks, proposing an energy formulation with both sparse reconstruction and class discrimination components, jointly optimized during dictionary learning. …”

Inequality and the 1% by Dorling, D

“…Inequality in the UK is increasing; more and more people are driven towards the poverty line. Even before birth, being born outside the 1% will have dramatic impact on the rest of your life: it will reduce your life expectancy, educational and work prospects, as well as your mental health. …”

Generative artificial intelligence : exploring the power and potential of generative AI / by Solanki, Shivam R., author 654859, Khublani, Drupad K., author, SpringerLink (Online service)

“…Then the book switch gears to dive into generative text models, exploring the concepts of Large Language Models (LLMs), natural language generation (NLG), fine-tuning, prompt tuning, and reinforcement learning. …”
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Public opinion trend analysis on nuclear energy via aspect-based sentiment analysis methods by Huang, Fan

“…In general, we built a system based on the ABSA Deep Learning model to make fine-grained and topic-specific sentiment analyses on public opinion trends. …”
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The Future of Service-Learning : New Solutions for Sustaining and Improving Practice / by Strait, Jean R., 1965-, editor 656157, Lima, Marybeth, 1965-, editor 656195, Furco, Andrew, editor 656196, Taylor & Francis Group (Online service) 645650

“…Further chapters offer a new blueprint for funding to achieve sustainability; examples of international service learning from a European perspective; a case study and framework for using on-line formats to extend the reach of a program; raise the urgent issue of the experiences and contributions of underrepresented students; and present the rationale and processes for developing effective student-led evaluation of programs.…”
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Crossing and intersecting families of geometric graphs on point sets by Álvarez-Rebollar, J. L., Cravioto-Lagos, J., Marín, N., Solé-Pi, O., Urrutia, J.

“…Let S be a set of n points in the plane in general position. Two line segments connecting pairs of points of S cross if they have an interior point in common. …”
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21W.742J / SP.575J / WGS.575J Writing About Race, Spring 2007 by Faery, Rebecca Blevins

“…Du Bois wrote that "...the problem of the Twentieth Century is the problem of the color line." A century after Du Bois penned those words, most Americans would agree that at the beginning of the twenty-first century, the color line remains one of our most pressing social issues. …”
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Graph embeddings on gene ontology annotations for protein-protein interaction prediction by Zhong, Xiaoshi, Rajapakse, Jagath Chandana

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Validation of the Needs Assessment of Family Caregivers - cancer scale in an Asian population by Yang, Winson Fu Zun, Liu, Jianlin, Chan, Yiong Huak, Griva, Konstadina, Kuparasundram, Sangita, Mahendran, Rathi

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