Amino acids stimulate the endosome-to-Golgi trafficking through Ragulator and small GTPase Arl5 by Shi, Meng, Chen, Bing, Mahajan, Divyanshu, Boh, Boon Kim, Zhou, Yan, Dutta, Bamaprasad, Tie, Hieng Chiong, Sze, Siu Kwan, Wu, Geng, Lu, Lei

“…By testing components of the AA-stimulated mTORC1 signaling pathway, we demonstrate that SLC38A9, v-ATPase and Ragulator, but not Rag GTPases and mTORC1, are essential for the AA-stimulated trafficking. Arl5, an ARF-like family small GTPase, interacts with Ragulator in an AA-regulated manner and both Arl5 and its effector, the Golgi-associated retrograde protein complex (GARP), are required for the AA-stimulated trafficking. …”
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What Dicey forgot by Barber, NW

“…For over a century, Dicey’s account of the rule of law dominated constitutional scholarship and, like any successful academic exercise, has not lacked critics. …”

Numerical modelling of detonation reaction zone of nitromethane by EXPLO5 code and wood and kirkwood theory by Štimac, Barbara, Chan, Serene Hay Yee, Kunzel, Martin, Muhamed Suceska

“…The measured particle velocity profile of NM shows the existence of a sharp spike followed by a rapid drop over the first 5-10 ns (fast reaction). …”
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Lead federated neuromorphic learning for wireless edge artificial intelligence by Yang, Helin, Lam, Kwok-Yan, Xiao, Liang, Xiong, Zehui, Hu, Hao, Niyato, Dusit, Poor, H. Vincent

“…This paper proposes a lead federated neuromorphic learning (LFNL) technique, which is a decentralized energy-efficient brain-inspired computing method based on spiking neural networks. The proposed technique will enable edge devices to exploit brain-like biophysiological structure to collaboratively train a global model while helping preserve privacy. …”
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Cost-effectiveness of MRI targeted biopsy strategies for diagnosing prostate cancer in Singapore by Cheng, Li-Jen, Soon, Swee Sung, Tan, Teck Wei, Tan, Cher Heng, Lim, Terence Sey Kiat, Tay, Kae Jack, Loke, Wei Tim, Ang, Bertrand, Chiong, Edmund, Ng, Kwong

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Tracking oxidation-induced alterations in fibrin clot formation by NMR-based methods by Lau, Wai-Hoe, White, Nathan J., Yeo, Tsin Wen, Gruen, Russell L., Pervushin, Konstantin

“…Molecular dynamics suggests that methionine oxidation poses a mechanistic link between oxidative stress and coagulation through protofibril lateral aggregation by disruption of AαC domain structures. …”
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Invisibility Dips of Near-Field Energy Transport in a Spoof Plasmonic Metadimer by Gao, Fei, Gao, Zhen, Luo, Yu, Zhang, Baile

“…Invisibility dips, i.e., minima in scattering spectrum associated with asymmetric Fano-like line-shapes, have been predicted with transformation optics in studying strong coupling between two plasmonic nanoparticles. …”
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Employment of a high throughput functional assay to define the critical factors that influence vaccine induced cross-variant neutralizing antibodies for SARS-CoV-2 by Gu, Yue, Shunmuganathan, Bhuvaneshwari, Qian, Xinlei, Gupta, Rashi, Tan, Rebecca S. W., Kozma, Mary, Purushotorman, Kiren, Murali, Tanusya M., Tan, Nikki Y. J., Preiser, Peter Rainer, Lescar, Julien, Nasir, Haziq, Somani, Jyoti, Tambyah, Paul A., Smith, Kenneth G. C., Renia, Laurent, Ng, Lisa F. P., Lye, David C., Young, Barnaby E., MacAry, Paul A.

“…We also present an accurate quantitation of serological responses for SARS-CoV-2 that exploits a unique set of in-house, recombinant human monoclonal antibodies targeting the viral Spike and nucleocapsid proteins and demonstrate a reduction in neutralizing antibody titres across all groups 6 months post-vaccination. …”
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SARS-CoV-2 accessory protein 7b forms homotetramers in detergent by Surya, Wahyu, Queralt-Martin, Maria, Mu, Yuguang, Aguilella, Vicente M., Torres, Jaume

“…The SARS-CoV-2 genome, like its predecessor SARS-CoV, contains open reading frames that encode accessory proteins involved in virus-host interactions active during infection and which likely contribute to pathogenesis. …”
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A hand-targeted auxiliary personal protective equipment for intervention of fomite transmission of viruses by Tan, Justin Kok Soon, Song, Shang Wei, Zeng, Jialiu, Lo, Chih Hung

“…Compared to conventional glove materials, FlexiPalm demonstrated enhanced mechanical durability and breathability, comparable hydrophobicity, and displayed a minimal adsorption of SARS-CoV-2 spike protein and virus-like particles (VLP). Importantly, FlexiPalm was found to bind significantly less viral protein and VLP than artificial human skin, confirming its ability to reduce viral contamination. …”
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Electromagnetic interference caused by electric currents in power cables by Goh, Tian Soon.

“…Exposure comes from various sources like power line outside the house,transformer near or inside the building, electrical cables for transmission. …”
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A novel bearingless interior permanent magnet slice motor for pump* by Kant, Krishan, Weinreb, Benjamin S., Hegy, Michael, Gartner, Mark, Trumper, David L.

“…FE simulations are also used to obtain other parameters like force and torque constant, and magnetic stiffness for designing control. …”
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Investigating viral glycosylation pathways for drug and vaccine development by Brun, J

“…Chapter 4 focuses on the site-specific glycosylation occupancy, and N- and O-glycan structures attached to virion derived SARS-CoV-2 spike glycoproteins. This glycan signature was compared to a stabilised prefusion trimeric spike, to a monomeric subunit of spike (S1) and to an antigen of a non-stabilised vaccine candidate, revealing subunit shedding of the S1 glycoprotein for the vaccine candidate. …”

Observation of an acoustic octupole topological insulator by Xue, Haoran, Ge, Yong, Sun, Hong-Xiang, Wang, Qiang, Jia, Ding, Guan, Yi-Jun, Yuan, Shou-Qi, Chong, Yidong, Zhang, Baile

“…Berry phase associated with energy bands in crystals can lead to quantised observables like quantised dipole polarizations in one-dimensional topological insulators. …”
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High-performance thermomagnetic generator controlled by a magnetocaloric switch by Liu, Xianliang, Chen, Haodong, Huang, Jianyi, Qiao, Kaiming, Yu, Ziyuan, Xie, Longlong, Ramanujan, Raju V., Hu, Fengxia, Chu, Ke, Long, Yi, Zhang, Hu

“…This makes it not only have the advantage of flux reversal of the pretzel-like topology, but also present a simpler design, lower magnetic stray field, and higher performance by using less magnetocaloric material than preceding devices. …”
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Single-cell laser emitting cytometry for label-free nucleolus fingerprinting by Fang, Guocheng, Qiao, Zhen, Huang, Luqi, Zhu, Hui, Xie, Jun, Zhou, Tian, Xiong, Zhongshu, Su, I-Hsin, Jin, Dayong, Chen, Yu-Cheng

“…The laser emission image provides insights into structural inhomogeneity, temporal fluid-like dynamics, and pathological application. Lasing spectral fingerprint depicts the quantity and size of nucleoli within a single cell, showcasing the label-free flow cytometry for nucleolus. …”
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Study on the effects of indoor air quality on the cognitive abilities of youths in Singapore by Chua, Elena Mei Yan

“…Although there have been several studies on Indoor Air Quality, not much has been done on how other types of pollutants like Formaldehyde, VOC, Ground Level Ozone and PM affect cognitive abilities of youths in a tropical climate like Singapore. …”
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Small sample sizes reduce the replicability of task-based fMRI studies by Turner, Benjamin O., Paul, Erick J., Miller, Michael B., Barbey, Aron K.

“…Thus, our results join the existing line of work advocating for larger sample sizes. …”
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Clinical implementation of an oncology-specific family health history risk assessment tool by Fung, Si Ming, Wu, Ryanne R., Myers, Rachel A., Goh, Jasper, Ginsburg, Geoffrey S., Matchar, David, Orlando, Lori A., Ngeow, Joanne

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Pre-failure strain localization in siliclastic rocks: a comparative study of laboratory and numerical approaches by Bianchi, Patrick, Selvadurai, Paul Antony, Zilio, Dal Luca, Vásquez, Antonio Salazar, Madonna, Claudio, Gerya, Taras, Wiemer, Stefan

“…These simulations revealed three distinct stages of preparatory processes: (i) highly dissipative fronts propagated towards the middle of the sample correlating with the observed acoustic emission locations; (ii) dissipative regions were individuated in the middle of the sample and could be linked to a discernible decrease of the P-wave velocities; (iii) a system of conjugate bands formed, coalesced into a single band that grew from the center towards the sample surface and was interpreted to be representative for the preparation of a weak plane. …”
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