Pick one, but be quick : 5' splice sites and the problems of too many choices by Roca, Xavier, Krainer, Adrian R., Eperon, Ian C.

“…Splice site selection is fundamental to pre-mRNA splicing and the expansion of genomic coding potential. 5′ Splice sites (5′ss) are the critical elements at the 5′ end of introns and are extremely diverse, as thousands of different sequences act as bona fide 5′ss in the human transcriptome. …”
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Binding of TCR multimers and a TCR-like antibody with distinct fine-specificities is dependent on the surface density of HLA complexes by Low, Jianrong L., Gehring, Adam J., Kranz, David M., Grotenbreg, Gijsbert M., Yau, Yin Hoe, Shochat, Susana Geifman, Bertoletti, Antonio, Naidoo, Anneta, Yeo, Gladys, Ho, Zi Zong

“…In line with this, we report the construction of a soluble tetrameric form of an αβ T cell receptor (TCR) specific for the HBV epitope Env183–191 restricted by HLA-A*02:01, and compare its avidity and fine-specificity with a TCR-like monoclonal antibody generated against the same HLA target. …”
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Development of hybrid robot-gripper for picking foods by Tee, Isaac

“…One such example is the picking and placing of food in large quantities. …”
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Identification and application of self-binding zipper-like sequences in SARS-CoV spike protein by Zhang, Si Min, Liao, Ying, Neo, Tuan Ling, Lu, Yanning, Liu, Ding Xiang, Vahlne, Anders, Tam, James Pingkwan

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Niemann-Pick type c disease: pathogenesis and therapy by Colaco, A

“…<p>Niemann-Pick disease Type C is a rare, lysosomal storage disorder caused by defects in either <em>NPC1</em> (95% of cases) or <em>NPC2</em>, and characterized by progressive neurodegeneration that ultimately results in premature death. …”

Intensity of stress singularity for the circumferential V-shape corner front of a three-dimensional diamond-like defect by Ping, X. ., Zhang, Y. X., Guo, Y. B., Xiao, Z. M., Jalde, J., Chen, M. C.

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Biocementation of fine-grained soil by Ong, Jun Hao

“…Further studies are required to understand the mechanisms of the MICP treatment for fine-grained soil.…”
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Discovering genetic modifiers in Niemann-Pick Disease Type C by Rodriguez-Gil, J

“…<p>Niemann-Pick Disease, Type C (NPC) is a rare, fatal neurodegenerative disorder characterized by lysosomal accumulation of unesterified cholesterol and sphingolipids. …”

Competitive strategies for small business in optical pick-up manufacturing by Ge, Guo Zheng, Zhang, Jing

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Tilted magnetisation for domain wall pinning in racetrack memory by Jin, Tianli, Tan, Funan, Ang, Calvin Ching Ian, Gan, Weiliang, Cao, Jiangwei, Lew, Wen Siang, Piramanayagam, S. N.

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Competitive anxiety among university ten-pin bowlers by Tan, Hui Xian

“…Minimal research was done on ten-pin bowling. This study aims to explore the relationship between competitive anxiety and performance in ten-pin bowlers and the role of experience in reducing debilitative anxiety levels. …”
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'I do not care a pin about it myself' by Honey, A

“…Andrew Honey, Book Conservator at the Bodleian, tells us of his excitement at discovering an original Jane Austen pin on our Sir Charles Grandison manuscript, and what this, and other pins, tell us about their use.…”

Development of an automatic fruit picking robot based on object detection algorithm by Wan, Jiaxin

“…In the agricultural field, especially in the process of harvest, it needs a lot of human resources to perform various tasks, such as picking fruits, which may be labor intensive. An effective robotics picking system can solve this problem to a large extent. …”
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Effect of recycled fine aggregates on concrete properties by Lau, Jing Xi.

“…In this project, the bulk of the experiment conducted is mainly based on the effects of recycled fine aggregates on the properties of hardened concrete. …”
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RF processing of ultra-fine bioceramic materials by Rajendra Kumar

“…This study investigates the radio-frequency plasma synthesis of ultra-fine bioceramic materials.…”
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Zeolitic imidazolate frameworks activate endosomal Toll-like receptors and potentiate immunogenicity of SARS-CoV-2 spike protein trimer by Alsaiari, Shahad K., Nadeef, Seba, Daristotle, John L., Rothwell, William, Du, Bujie, Garcia, Johnny, Zhang, Linzixuan, Sarmadi, Morteza, Forster, Timothy A., Menon, Nandita, Lin, Stacey Qiaohui, Tostanoski, Lisa H., Hachmann, Nicole, Wang, Erika Yan, Ventura, John D., Barouch, Dan H., Langer, Robert, Jaklenec, Ana

“…In this work, we report the Toll-like receptor agonist activity of a nanoscale adjuvant zeolitic imidazolate framework–8 (ZIF-8). …”
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Domain wall pinning through nanoscale interfacial Dzyaloshinskii-Moriya interaction by Kumar, Durgesh, Chan, Jianpeng, Piramanayagam, S. N.

“…We have also studied pinning in a device with five successive pinning sites. …”
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Walking like trees by Lim, Jonathan Yong Ern

“…Walking Like Trees was a year-long exploration of storytelling through the juxtaposition of text and image within the medium of the printed graphic novel. …”
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Rapid and Scalable Production of Functional SARS-CoV-2 Virus-like Particles (VLPs) by a Stable HEK293 Cell Pool by Puarattana-aroonkorn, Sitthiphol, Tharakaraman, Kannan, Suriyawipada, Disapan, Ruchirawat, Mathuros, Fuangthong, Mayuree, Sasisekharan, Ram, Artpradit, Charlermchai

“…We employed the membrane, envelope, and highly immunogenic spike proteins of SARS-CoV-2 to produce virus-like particles (VLPs) using the HEK293-F cell line as a host system with an economical transfection reagent. …”
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Antigen presentation dynamics shape the antibody response to variants like SARS-CoV-2 Omicron after multiple vaccinations with the original strain by Yang, Leerang, Van Beek, Matthew, Wang, Zijun, Muecksch, Frauke, Canis, Marie, Hatziioannou, Theodora, Bieniasz, Paul D, Nussenzweig, Michel C, Chakraborty, Arup K

“…The Omicron variant of SARS-CoV-2 is not effectively neutralized by most antibodies elicited by two doses of mRNA vaccines, but a third dose increases anti-Omicron neutralizing antibodies. …”
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