Molecular determinants of chromatin accessibility at CpG islands in mouse embryonic stem cells by King, H

“…To examine potential mechanisms by which hypomethylated DNA could serve to promote chromatin accessibility, I profiled chromatin accessibility in mouse ESCs lacking various chromatin-modifying proteins which are normally enriched at CGIs, with the histone demethylases KDM2A/B linked to maintaining open chromatin at CGIs. As an alternative approach to understanding the causes of chromatin accessibility in mouse ESCs, I examined the mechanism by which the pioneer transcription factor OCT4 is able to access previously inaccessible chromatin, and reveal that it requires the chromatin remodeller BRG1 to remodel chromatin and facilitate transcription factor binding at distal regulatory elements. …”

Estimating global demand for land-based transportation services using the shared socioeconomic pathways scenario framework by Nkiriki, J, Jaramillo, P, Williams, N, Davis, A, Armanios, DE

“…To address this limitation, we develop a log-log regression model linking socioeconomic variables with demand for land-based passenger and freight transport services. …”

Small-island interactions: pottery from Roman Malta by Anastasi, M

“…These data were also fed into a series of network analyses, which plotted the common pottery links shared between small-island and mainland sites in the region. …”

Transcriptional brain networks and their key regulators across the human lifespan by Wehrspaun, CC

“…In the second project, I demonstrated that gene clusters linked to neurogenesis during fetal life show moderate to strong preservation in the human adult brain. …”

The amygdala and the pursuit of future rewards by Johnson, ST, Grabenhorst, F

“…Success and failure in these processes have been linked to differential life outcomes and psychiatric conditions. …”

Identifying the sources of intestinal colonization with extended-spectrum β-lactamase-producing Escherichia coli in healthy infants in the community by Amin, MB, Hoque, KI, Roy, S, Saha, SR, Islam, MR, Julian, TR, Islam, MA

“…Overall, this study provides empirical evidence that ESBL-Ec colonization in children is linked to the colonization status of mothers and exposure to the household environments contaminated with ESBL-Ec. …”

Neural processing in the primary auditory cortex following cholinergic lesions of the basal forebrain in ferrets by Nodal, FR, Leach, ND, Keating, P, Dahmen, JC, Zhao, D, King, AJ, Bajo, VM

“…<p>Cortical acetylcholine (ACh) release has been linked to various cognitive functions, including perceptual learning. …”

Unlocking the gates: pedestrian route choice in transforming metro station paid areas into mobile public spaces by Chan, HY, Tse, W-Y, Chen, A

“…Using three pairs of interconnected metro stations in Hong Kong&mdash;two linked by private paid walkways (stated preference) and one by public unpaid walkways (revealed preference)&mdash;a questionnaire survey (<em>N</em>=419) and discrete choice modeling were conducted. …”

Perceptions of meteorological phenomena in ancient Egypt by Jensen, CL

“…<p>Perception of landscape has become crucial for how we recreate ancient experience, linking landscape to concepts of embodiment, identity, and dwelling, but the perception of weather has been absent from these discussions. …”

Veterinary extension services in the integration program of cattle farming and oil palm in Target Area Concentration (TAC) by Man, Norsida, Siaw, Shin Yee, Yusuf, Munifah Siti Amira, Azizah, Siti

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Strain-Dependent Effects on Confinement of Folded Acoustic and Optical Phonons in Short-Period (XC)m/(YC)n with X,Y (≡Si, Ge, Sn) Superlattices by Talwar, Devki N., Semone, Sky, Becla, Piotr

“…These simulated changes are linked to the localization of atomic displacements constrained either by the XC/YC or YC/XC unabrupt interfaces. …”
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Exploring green gentrification in 28 global North cities: the role of urban parks and other types of greenspaces by Triguero-Mas, Margarita, Anguelovski, Isabelle, Connolly, James J T, Martin, Nick, Matheney, Austin, Cole, Helen V S, Pérez-Del-Pulgar, Carmen, García-Lamarca, Melissa, Shokry, Galia, Argüelles, Lucía, Conesa, David, Gallez, Elsa, Sarzo, Blanca, Beltrán, Miguel Angel, López Máñez, Jesúa, Martínez-Minaya, Joaquín, Oscilowicz, Emilia, Arcaya, Mariana C, Baró, Francesc

“…Although cities globally are increasingly mobilizing re-naturing projects to address diverse urban socio-environmental and health challenges, there is mounting evidence that these interventions may also be linked to the phenomenon known as green gentrification. …”
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Age- and Sex-Based Developmental Biomarkers in Eye Movements by Carrick, Frederick Robert, Hunfalvay, Melissa, Bolte, Takumi, Azzolino, Sergio F., Abdulrahman, Mahera, Hankir, Ahmed, Antonucci, Matthew M., Al-Rumaihi, Nouf

“…This study represents significant progress in linking eye movements with brain function and clinical syndromes, allowing researchers and clinicians to stratify individuals by age and sex.…”
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Assessing the origin of and potential for international spread of Chikungunya virus from the Caribbean by Khan, Kamran, Bogoch, Isaac, Brownstein, John S., Miniota, Jennifer, Nicolucci, Adrian, Hu, Wei, Nsoesie, Elaine O., Cetron, Martin, Creatore, Maria Isabella, German, Matthew, Wilder-Smith, Annelies

“…Conclusion: The rapidly evolving outbreak of chikungunya in the Caribbean poses a growing risk to countries and areas linked by air travel, including the United States where competent Aedes mosquitoes exist. …”
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Integrated transcriptomics, metabolomics, and lipidomics profiling in rat lung, blood, and serum for assessment of laser printer-emitted nanoparticle inhalation exposure-induced di... by Guo, Nancy Lan, Poh, Tuang Yeow, Pirela, Sandra, Farcas, Mariana T., Chotirmall, Sanjay Haresh, Tham, Wai Kin, Adav, Sunil S., Ye, Qing, Wei, Yongyue, Shen, Sipeng, Christiani, David C., Ng, Kee Woei, Thomas, Treye, Qian, Yong, Demokritou, Philip

“…Furthermore, the systematic analysis revealed PEPs-induced transcriptomic changes linking to other disease risks in rats, including diabetes, congenital defects, auto-recessive disorders, physical deformation, and carcinogenesis. …”
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Oncofetal HMGA2 attenuates genotoxic damage induced by topoisomerase II target compounds through the regulation of local DNA topology by Ahmed, Syed Moiz, Dröge, Peter

“…Here, we demonstrate that HMGA2 significantly enhanced the DNA supercoil relaxation activity of the drug target TOP2A and that this activator function is mechanistically linked to HMGA2’s known ability to constrain DNA supercoils within highly compacted ternary complexes. …”
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Three essays on national and organizational cultures by Kawasaki, Shota

“…Chapter 2 illustrates a novel pathway linking employees’ perceptions of organizational cultural strength to job satisfaction and organizational commitment via organizational nostalgia (i.e., one’s sentimental longing or wistful affection for past organizational events). …”
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Barriers and leverage points for seeing alcohol differently in integrated care systems in England: a senior stakeholder interview study by Madden, Mary, Stewart, Duncan, McCambridge, Jim

“…Conclusions: There is much to do to create a joined-up, system-wide approach to alcohol, and thus a strong case for a national NHS alcohol strategy to guide ICS decision-making, addressing links between NHS work and public health.…”
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Hepatic effects of prolonged oral administration of Aqueous extracts from Trigonella foenum-graecum (Fenugreek) seeds explored through pathology techniques by Okorie, Nnaemeka, Ibe, Onyekachi Ewa, Okekpa, Simon Imakwu, Nwakpa, Anthony Chukwudi, Agom, Dansy Daniel, Pauline, Iyke-Ogbo, Adaeze, Obi Laura, Mmesomachi, Uche Bethel, Nyirahafashimana, Valentine, Obi, Ihuoma A.

“…Introduction: The escalating global prevalence of complementary and alternative medicine is often linked to the financial challenges of conventional healthcare in developing nations. …”
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Fabrication of bilayer nanofibrous-hydrogel scaffold from bacterial cellulose, PVA, and gelatin as advanced dressing for wound healing and soft tissue engineering by Khan, Rawaiz, Aslam Khan, Muhammad Umar, Stojanović, Goran M., Javed, Aneela, Haider, Sajjad, Abd. Razak, Saiful Izwan

“…FTIR confirmed cross-linking of both the top and bottom layers, and SEM showed porous structure for the bottom layer, random deposition of NFs on the surface, and aligned NFs in the cross section. …”
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