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Mice deficient in PAPP - a show resistance to the development of diabetic nephropathy
Published 2013“…Kidneys from diabetic WT mice showed multiple abnormalities including thickening of Bowman's capsule (100% of mice), increased glomerular size (80% of mice), tubule dilation (80% of mice), and mononuclear cell infiltration (90% of mice). …”
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Mylk3 null C57BL/6N mice develop cardiomyopathy, whereas Nnt null C57BL/6J mice do not
Published 2020“…The C57BL/6J and C57BL/6N mice have well-documented phenotypic and genotypic differences, including the infamous nicotinamide nucleotide transhydrogenase (Nnt) null mutation in the C57BL/6J substrain, which has been linked to cardiovascular traits in mice and cardiomyopathy in humans. …”
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NNT is a key regulator of adrenal redox homeostasis and steroidogenesis in male mice
Published 2018“…Certain substrains of C57BL/6 mice contain a spontaneously occurring inactivatingmutation and display glucocorticoid deficiency along with glucose intolerance and reduced insulin secretion. …”
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A study of the legal effect of the main provisions of the income tax treaty between France and the United Kingdom
Published 1984“…This thesis analyses the taxation rules applicable to different classes of income and the respective rights to tax of both the state of source and the state of residence. Its main objective is to provide an exhaustive explanation of the rules of taxation, together with an illustration of their practical operation. …”
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The novel BRDT inhibitor NHWD870 shows potential as a male contraceptive in mice
Published 2022“…In this paper, we report a new generation of BET family inhibitor, NHWD870, that provide a complete and reversible contraceptive effect in mice which is stronger than that of JQ1 and its synthesized derivatives. …”
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Effect of adding global postural re-education to Kendall exercises for treating asymptomatic forward head posture: a single-blinded randomized controlled trial
Published 2025“…Conclusions: The added effect GPR technique to Kendall exercises significantly improved CVA, CROM, NDI, chest expansion, and spinal mobility in subjects with FHP.…”
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Antivirals for broader coverage against human coronaviruses
Published 2024“…Spike is also not applicable for targeting other HCoVs as these are not well-conserved sequences among human CoVs. …”
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Biomechanical evaluation and new improvement on ankle external fixator
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Holocene environmental change in the Scottish Highlands: multi-proxy evidence from blanket peats
Published 1997“…This thesis seeks to investigate the Holocene environmental history of two areas of Northern Scotland with specific reference to the evidence for pine woodland density variations and tree-line dynamics. …”
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Photonic controlled metasurface for intelligent antenna beam steering applications including 6G mobile communication systems
Published 2023“…This paper presents a novel metasurface antenna whose radiation characteristics can be remotely controlled by optical means using PIN photodiodes. The proposed reconfigurable antenna is implemented using a single radiating element to minimize the size and complexity. …”
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Novel opto-electronic and plastic fibre sensors
Published 1998“…The middle POF is coupled to a red LED and emits light onto a flat target with the two outer fibres receiving the reflected light from the target and guiding it to two silicon PIN photodiodes. Theoretical investigations on the behaviour of the sensor are presented for ranges between 0 mm and 100 mm, and for targets with different reflectivities. …”
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Telomere oxidation status (TOS) is correlated with relative telomere length (RTL) across different mouse tissues but not with nicotinamide nucleotide transhydrogenase (Nnt) status
Published 2023“…We investigated whether Nnt deficient mice have reduced TL and display markers of TOS compared to WT and rescued mice and whether this was tissue specific.…”
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Electrical breakdown and structural characterization in synthetic resins using optical techniques
Published 1992“…The early tree growth is shown to be driven by the high electrical field near the pin tip, which is itself dependent on the pin-plane electrode separation as well as the applied voltage. …”
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An investigation of defect formation and growth in epoxy resin using light scattering methods
Published 1989“…This consists of a densely crossllnked core of mainly diester crosslinks, surrounded by a less densely crosslinked network containing more ether crosslinks. …”
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Thesis