Epitope mapping of antibodies induced with a conserved rhinovirus protein generating protective anti-rhinovirus immunity by Narean, Janakan Sam, Glanville, Nicholas, Nunn, Christine M., Niespodziana, Katarzyna, Valenta, Rudolf, Johnston, Sebastian L., McLean, Gary R.

“…We demonstrated previously that immunising mice with highly conserved VP4 and VP2 regions of the RV polyprotein (RV-A16 VP0) generated cross-reactive immunity to RV in vivo. …”
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Sphingosine-1-phosphate lyase mutations cause primary adrenal insufficiency and steroid-resistant nephrotic syndrome by Prasad, Rathi, Hadjidemetriou, Irene, Maharaj, Avinaash, Meimaridou, Eirini, Buonocore, Federica, Saleem, Moin, Hurcombe, Jenny, Bierzynska, Agnieszka, Barbagelata, Eliana, Bergadá, Ignacio, Cassinelli, Hamilton, Das, Urmi, Krone, Ruth, Hacihamdioglu, Bulent, Sari, Erkan, Yesilkaya, Ediz, Storr, Helen L., Clemente, Maria, Fernandez-Cancio, Monica, Camats, Nuria, Ram, Nanik, Achermann, John C., Van Veldhoven, Paul P., Guasti, Leonardo, Braslavsky, Debora, Guran, Tulay, Metherell, Louise A.

“…In total, 8 patients were investigated, some of whom also manifested other features, including ichthyosis, primary hypothyroidism, neurological symptoms, and cryptorchidism. Sgpl1-/- mice recapitulated the main characteristics of the human disease with abnormal adrenal and renal morphology. …”
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Low-loss paper-substrate triple-band-frequency reconfigurable microstrip antenna for sub-7 GHz applications by Singh, Ajit Kumar, Mahto, Santosh Kumar, Sinha, Rashmi, Alibakhshikenari, Mohammad, Al-Gburi, Ahmed Jamal Abdullah, Ahmad, Ashfaq, Kouhalvandi, Lida, Virdee, Bal Singh, Dalarsson, Mariana

“…In this paper, a low-cost resin-coated commercial-photo-paper substrate is used to design a printed reconfigurable multiband antenna. The two PIN diodes are used mainly to redistribute the surface current that provides reconfigurable properties to the proposed antenna. …”
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Highly infectious prions are not directly neurotoxic by Benilova, Iryna, Reilly, Madeleine, Terry, Cassandra, Wenborn, Adam, Schmidt, Christian, Marinho, Aline T., Risse, Emmanuel, Al-Doujaily, Huda, Wiggins De Oliveira, Michael, Sandberga, Malin K., Wadsworth, Jonathan D. F., Jat, Parmjit S, Collinge, John

“…We fur- ther show that treatment of brain homogenates from prion-infected mice with sodium lauroylsarcosine destroys toxicity without diminish- ing infectivity. …”
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Development of niosome-loaded bromelain as anti-inflammatory agent by Chermahini, Siavash Hosseinpour

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Synthesis and characterization of spions-bromelan-folic acid on folic acid receptor positive cancer model by Nasiri, Rozita

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Measurement and modelling of operational amplifier power supply rejection by Brinson, Mike, Faulkner, D. J.

“…Measured results for 741 and pin-compatible operational amplifiers are tabulated. …”
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Decoy ACE2-expressing extracellular vesicles that competitively bind SARS-CoV-2 as a possible COVID-19 therapy by Inal, Jameel

“…As for SARS-CoV that caused the SARS 2003 epidemic, the receptor on host cells that promotes uptake, through attachment of the spike (S) protein of the virus, is angiotensin-converting enzyme 2 (ACE2). …”
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3rd order coupled-resonator bandpass filter assisted by Groove Gap-Waveguide technology for 26-GHz radio link diplexer by Alibakhshikenari, Mohammad, Parand, Peiman, Zidour, Ali, Virdee, Bal Singh, Longhi, Patrick, See, Chan Hwang, Limiti, Ernesto

“…Its unit-cells consist of a rectangular metal-pin which is connected to a bottom metal plate and its other side is electromagnetically coupled to a top plate with an air-gap of approximately λ/4 that creates a bandgap, preventing unwanted electromagnetic-wave propagation. …”
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Rapid quantification of SARS-CoV-2 neutralising antibodies using time- resolved fluorescence immunoassay by McLean, Gary R., Zhang, Yueke, Ndoyi, Rene, Martin, Adam, Winer, Julian

“…It also correlated well to spike receptor binding domain binding antibodies over a broad range of plasma dilutions. …”
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Performance of underside shaped concrete blocks for pavement by Mohamed, Azman

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A molecular docking study repurposes FDA approved iron oxide nanoparticles to treat and control COVID-19 infection by Abo-zeid, Yasmin, Ismail, Nasser S., McLean, Gary R., Hamdy, Nadia M.

“…Therefore, we performed a docking study to explore the interaction of IONPs (Fe2O3 and Fe3O4) with the spike protein receptor binding domain (S1-RBD) of SARS-CoV-2 that is required for virus attachment to the host cell receptors. …”
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Identification of similar epitopes between SARS-CoV-2 and Bacillus Calmette-Guérin: potential for cross-reactive adaptive immunity by Urbán, Szabolcs, Paragi, Gábor, Burián, Katalin, McLean, Gary R., Virok, Dezső P.

“…The SARS-CoV-2 T cell epitopes represented 16 SARS-CoV-2 proteins, the SARS-CoV-2 B cell epitopes represented 5 SARS-CoV-2 proteins, including the receptor binding domain of the spike glycoprotein. Conclusion: Altogether our results provide a mechanistic basis for the potential cross-reactive adaptive immunity that may exists between the two microorganisms.…”
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Decoding Covid-19 with the SARS-CoV-2 genome by Ellis, Phoebe, Somogyvári, Ferenc, Virok, Dezső P., Noseda, Michela, McLean, Gary R.

“…The critical determinant of the SARS-CoV-2 genome is the spike (S) gene encoding the viral structural protein that interacts with the host cell entry receptor ACE2. …”
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Electronically reconfigurable and conformal triband antenna for wireless communications systems and portable devices by Hussain, Musa, Ali, Esraa Mousa, Awan, Wahaj Abbas, Hussain, Niamat, Alibakhshikenari, Mohammad, Virdee, Bal Singh, Falcone, Francisco

“…This is achieved by connecting two open-ended stubs to a modified triangular patch radiator using PIN diodes. The antenna’s performance was optimized using a 3D electromagnetic solver and its performance was verified through measurements. …”
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A Novel MIMO antenna integrated with a solar panel and employing AI-equalization for 5G wireless communication networks by Hussein, Humam, Elmunim, Nouf Abd, Atasoy, Ferhat, Virdee, Bal Singh, Elwi, Taha A., Rashid, Nasr, Jayanthi, Renu Karthick Rajaguru, Alibakhshikenari, Mohammad, Limiti, Ernesto

“…We demonstrate that the directivity of this antenna array can be precisely electronically reconfigured using PIN diode switches. Additionally, we show the feasibility of integrating solar panels with the proposed MIMO antenna array. …”
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Prion 2016 poster abstracts by Terry, Cassandra, Wenborn, Adam, Gros, Nathalie, Sells, Jessica, Joiner, Susan, Hosszu, Laszlo L. P., Tattum, M. Howard, Panico, Silvia, Clare, Daniel K., Collinge, John, Saibil, Helen R., Wadsworth, Jonathan D. F.

“…Our preparations contain very high titres of infectious prions which faithfully transmit prion strain-specific phenotypes when inoculated into mice making them eminently suitable for detailed structural analysis. …”
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Cross-serotype immunity induced by immunization with a conserved rhinovirus capsid protein by Glanville, Nicholas, McLean, Gary R., Guy, Bruno, Lecouturier, Valerie, Berry, Catherine, Girerd, Yves, Gregoire, Christophe, Walton, Ross P., Pearson, Rebecca M., Kebadze, Tatiana, Burdin, Nicolas, Bartlett, Nathan W., Almond, Jeffrey W., Johnston, Sebastian L.

“…Similar cross-reactive responses were observed in the lungs of immunized mice after infection with heterologous RV strains. …”
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Animal models of human disease 2.0 by Lange, Sigrun, Inal, Jameel

“…A total of twenty-two papers were published, including two comprehensive reviews on the use of diverse animal models to advance translational research and twenty original research papers using more common and conventional laboratory animal models (mice, rats, rabbits) or other less frequent comparative models (dogs and plateau pikas). …”
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Recent advances in understanding mammalian prion structure: a mini review by Terry, Cassandra, Wadsworth, Jonathan D. F.

“…Recently, however, images of highly infectious PrP rods that produce prion-strain specific disease phenotypes in mice have been obtained using cryo-electron microscopy and atomic force microscopy. …”
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