Showing 1 - 20 results of 190 for search '((((pinn OR pingn) OR (mice OR spike)) OR spine) OR ((sspinal OR sspingal) OR (pin OR min)))', query time: 0.11s Refine Results
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    Mice deficient in PAPP - a show resistance to the development of diabetic nephropathy by Mader, Jessica R., Resch, Zachary T., McLean, Gary R., Mikkelsen, Jakob H., Oxvig, Claus, Marler, Ronald J., Conover, Cheryl A.

    Published 2013
    “…Kidneys from diabetic WT mice showed multiple abnormalities including thickening of Bowman's capsule (100% of mice), increased glomerular size (80% of mice), tubule dilation (80% of mice), and mononuclear cell infiltration (90% of mice). …”
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    Mylk3 null C57BL/6N mice develop cardiomyopathy, whereas Nnt null C57BL/6J mice do not by Williams, Jack L., Paudyal, Anju, Awad, Sherine, Nicholson, James, Grzesik, Dominika, Botta, Joaquin, Meimaridou, Eirini, Maharaj, Avinaash, Stewart, Michelle, Tinker, Andrew, Cox, Roger D., Metherell, Louise A.

    Published 2020
    “…The C57BL/6J and C57BL/6N mice have well-documented phenotypic and genotypic differences, including the infamous nicotinamide nucleotide transhydrogenase (Nnt) null mutation in the C57BL/6J substrain, which has been linked to cardiovascular traits in mice and cardiomyopathy in humans. …”
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    NNT is a key regulator of adrenal redox homeostasis and steroidogenesis in male mice by Meimaridou, Eirini, Goldsworthy, Michelle, Chortis, Vasileios, Fragouli, Elpida, Foster, Paul A., Arlt, Wiebke, Cox, Roger D., Metherell, Louise A.

    Published 2018
    “…Certain substrains of C57BL/6 mice contain a spontaneously occurring inactivatingmutation and display glucocorticoid deficiency along with glucose intolerance and reduced insulin secretion. …”
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    The novel BRDT inhibitor NHWD870 shows potential as a male contraceptive in mice by Wu, Sixian, Li, Xiaoliang, Shang, Lijun, Wu, Lvying, Li, Tongtong, Li, Peiyv, Ji, Zhiliang, Hou, Jianwen, Yin, Mingzhu, Xu, Wenming

    Published 2022
    “…In this paper, we report a new generation of BET family inhibitor, NHWD870, that provide a complete and reversible contraceptive effect in mice which is stronger than that of JQ1 and its synthesized derivatives. …”
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