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Dok3 restrains neutrophil production of calprotectin during TLR4 sensing of SARS-CoV-2 spike protein
Published 2023“…In this study, we showed that Dok3 adaptor restrains calprotectin production by neutrophils in response to SARS-CoV-2 spike (S) protein engagement of TLR4. Dok3 recruits SHP-2 to mediate the de-phosphorylation of MyD88 at Y257, thereby attenuating downstream JAK2-STAT3 signaling and calprotectin production. …”
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Journal Article -
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Effects of lumbar support to reduce discomfort during prolonged riding among motocyclists
Published 2015Subjects: Get full text
Thesis -
23
Bio-inspired categorization using event-driven feature extraction and spike-based learning
Published 2014“…Bio-inspired, cortex-like, spikebased features are obtained through event-driven convolution and neural competition. The extracted spike feature patterns are then classified by a network of leaky integrate-and-fire (LIF) spiking neurons, in which the weights are trained using tempotron learning rule. …”
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Conference Paper -
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Morphological learning in spiking neurons: a new hardware efficient maching learning method
Published 2014“…The latest developments in the research of spiking neural network models have shown that unlike the classic neural network models, these models communicate via precisely timed neuron spikes, thus making them a closer representation of the biological neurons. …”
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Final Year Project (FYP) -
25
Design of a hybrid neural spike detection algorithm for implantable integrated brain circuits
Published 2016Subjects: “…Spike…”
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Conference Paper -
26
Fish Motion Trajectories Detection Algorithm Based on Spiking Neural Network (S/O: 12893)
Published 2017“…This study proposes sequence learning for the fish motion trajectory by using the Spike-Time dependent Plasticity (STDP) in the Spiking Neural Networks (SNNs). …”
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Monograph -
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EEG data handling using AWS cloud computing for automatic spike detection in epilepsy patients
Published 2017“…In this work, we explore the feasibility of AWS-cloud based approach for handling large EEG data for automatic spike detection in epilepsy patients. The aim is to design a system which will allow neurologists to upload and download EEG data from any region for analysis purpose; in the future the data will be analysed by machine learning algorithms. …”
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Thesis -
31
新加坡酷儿运动的正常化策略 :粉红点的空间实践 = The normalization strategies of Singapore’s queer activism : the spatial practice of pink dot
Published 2016“…Pink Dot has attracted not only the queer community, but also the mainstream community. …”
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Final Year Project (FYP) -
32
Event-driven spiking neural networks using asynchronous-logic network-on-chip routers in field programmable gate array (FPGA)
Published 2023“…Compared with the second-generation neural network, SNN uses spikes to process information. The neuronal units in SNNs are only active when they receive or emit spikes, so it is event-driven, thus making it energy-efficient. …”
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Thesis-Master by Coursework -
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High-density lipoprotein function is modulated by the SARS-CoV-2 spike protein in a lipid-type dependent manner
Published 2023“…It is known that the SARS-CoV-2 spike (S) protein binds the HDL particle, probably depleting it of lipids and altering HDL function. …”
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Journal Article -
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新移民的跨国实践和离散论述 :孙侠(铃铛)个案研究 = Transnational practice and diasporic discourses of new immigrant : a case study on Sun Xia (Ling Dang)
Published 2017“…Sun Xia is also a poet whom goes by the pen name, Ling Dang. Through her works, she represents a unique diasporic group with multiple identities who identifies with two cultures under the transnational experience. …”
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Final Year Project (FYP) -
36
Efficient multi-scale representation of visual objects using a biologically plausible spike-latency code and winner-take-all inhibition
Published 2023“…We demonstrate that a network of 200 spiking neurons tuned to three SFs can efficiently represent objects with as little as 15 spikes per neuron. …”
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Article -
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Zeolitic imidazolate frameworks activate endosomal Toll-like receptors and potentiate immunogenicity of SARS-CoV-2 spike protein trimer
Published 2024“…The intrinsic adjuvant properties of ZIF-8, along with the efficient delivery and biomimetic presentation of a severe acute respiratory syndrome coronavirus 2 spike protein receptor-binding domain trimer, primed rapid humoral and cell-mediated immunity in a dose-sparing manner. …”
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Article -
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The cellular characterization of SARS-CoV-2 spike protein in virus-infected cells using the receptor binding domain binding specific human monoclonal antibodies
Published 2022“…While all five antibodies bound conformational-specific epitopes within SARS-CoV-2 spike (S) protein, only PD5, PD7, and SC23 were able to bind to the receptor binding domain (RBD). …”
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Journal Article -
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Virus-like particles of nodavirus displaying the receptor binding domain of SARS-CoV-2 spike protein: a potential VLP-based COVID-19 vaccine
Published 2023“…The receptor binding domain (RBD) of the virus spike (S) glycoprotein has been extensively used in vaccine development due to its role in host cell attachment and penetration. …”
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Article -
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Low-cost incubator for live-cell imaging
Published 2024Subjects: Get full text
Final Year Project (FYP)