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2401
MDM2 functions as a timer reporting the length of mitosis
Published 2025“…Because MDM2 has a short half-life and ongoing protein synthesis is therefore necessary to maintain its steady-state concentration, the amount of MDM2 gradually falls during mitosis but normally remains above a critical threshold for p53 regulation at the onset of G1. …”
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2402
Structural study of enteroviruses
Published 2023“…Indeed, many structural details of enterovirus infection, immune response and life cycle remain unknown. Solving these structural mysteries may provide crucial information that aids the elimination of these infectious particles.…”
Thesis -
2403
TransLeish: Identification of membrane transporters essential for survival of intracellular Leishmania parasites in a systematic gene deletion screen
Published 2025“…For the protozoan parasite Leishmania, completion of its life cycle requires sequential adaptation of cellular physiology and nutrient scavenging mechanisms to the different environments of a sand fly alimentary tract and the acidic mammalian host cell phagolysosome. …”
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2404
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2405
Important mathematical competences for students in the age of generative artificial intelligence: proof comprehension and evaluation, and ChatGPT
Published 2024“…The rapid growth and popularity of generative artificial intelligence has influenced all aspects of life and education, including mathematics education. …”
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2406
Disciplining the state: virtue, violence, and state-making in modern China
Published 2007“…During each period, central authorities introduced—not without resistance—institutional change designed to extend the reach of central control over local political life. The successes and failures of state-building in each case rested largely upon the ability of each regime to construct itself as an autonomous moral agent both separate from and embedded in an imagined political community. …”
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2407
Ex vivo expansion and genetic manipulation of mouse hematopoietic stem cells in polyvinyl alcohol-based cultures
Published 2023“…Self-renewing multipotent hematopoietic stem cells (HSCs) are an important cell type due to their abilities to support hematopoiesis throughout life and reconstitute the entire blood system following transplantation. …”
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2408
A surface transporter family conveys the trypanosome differentiation signal
Published 2009“…The parasites causing African sleeping sickness respond to citrate or cis-aconitate (CCA) to initiate life-cycle development when transmitted to their tsetse fly vector. …”
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2409
Rationale and concerns for using JAK inhibitors in axial spondyloarthritis
Published 2024“…Axial spondyloarthritis (axSpA) is a lifelong disease that has a significant impact on quality of life. It is initially manifested by inflammatory back pain and can be associated with inflammation in other body parts, such as the eyes, bowel and skin. …”
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2410
Reading and translating with scripture - a study of textual growth in the Enochic theophany in the Book of the Watchers 1:1-9
Published 2022“…Rather than dismissing these shifts and developments in the text as ‘corruptive’ or ‘degenerative’ features in the history and life of the Enochic theophany, the methodology employed in this project envisages them as vital and generative features that reveal how the text was read, interpreted, and re-signified as it was translated and transmitted. …”
Thesis -
2411
Addressing Factors that Impact Sexual Well-Being and Intimacy in IBD Patients
Published 2025“…Recent Findings: Recent clinical surveys of practicing gastroenterologists document that clinicians should routinely address sexual health when addressing patient reported outcomes but very few actually make direct inquiry or suggest management into this important aspect of human life. Example ‘patter’ are suggested to clinicians to demonstrate how to introduce the subject of sexual intimacy and well-being and engender patient trust on this sensitive topic. …”
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2412
Can robotic AI systems be virtuous and why does this matter?
Published 2022“…The growing use of social robots in times of isolation refocuses ethical concerns for Human–Robot Interaction and its implications for social, emotional, and moral life. In this article we raise a virtue-ethics-based concern regarding deployment of social robots relying on deep learning AI and ask whether they may be endowed with ethical virtue, enabling us to speak of “virtuous robotic AI systems”. …”
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2413
Navigating the real world: a grounded theory-based exploration of autistic adolescents identity formation in Marcelo in the real world
Published 2023“…By using the grounded theory and drawing on ideas from disability studies and social identity theory, the research demonstrates that parental guidance, encouragement and normal treatment of friends, and exposure to conflicts and contradictions are the most significant factors and can help autistic adolescents understand social life, improve social competence, and obtain power and control in social relations, promoting positive identity formation. …”
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2414
Influence of socioeconomic activities on house form and settlement patterns among the Tiv people of central Nigeria
Published 2024“…More studies are required to reveal the sociocultural values of Nigerian Indigenous housing for sustainable development of their built environments and way of life.…”
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2415
A Single Period Deterministic Inventory Routing Model for Solving Problems in the Agriculture Industry
Published 2022“…This research proposed an optimisation model to present the actual problem that happened in a real-life situation. The simulation of the transportation problem was developed using an algebraic modelling language which is called a mathematical programming language (AMPL) to determine an optimal solution. …”
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Article -
2416
Novel method of probe design for characterising unclassified microbial taxa in wastewater
Published 2017“…One apparent advantage is the broadening of our knowledge on the prokaryotic tree of life, which can subsequently lead to the design of more accurate PCR primers and FISH probes. …”
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Thesis -
2417
Ethics in Psychotherapy and Counseling : A Practical Guide /
Published 2021“…Once referred to as the "conscience of psychology," this must-read book also includes: A thorough introduction to the foundations of psychotherapeutic ethics, including ethics in real life, ethics in theories and codes, cultural context, ethical decision making, and moral courage; An exploration of common sources of ethical problems and pitfalls, including: pseudoscience, ethical fallacies, ethical judgement errors, language and rationalizations; Practical discussions of special topics in ethics, including informed consent and informed refusal, using strategies for self-care, responding to ethics, licensing, and malpractice complaints, and confidentiality; In-depth examination of timely issues, including sexual attraction to patients, digital therapy, and responding to suicidal risk. …”
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software, multimedia -
2418
Project Management in the Construction Industry : From Concept to Completion /
Published 2024“…Written by a longtime professional and author with diversified and international experience in academia and industry, Project Management in the Construction Industry covers sample topics such as: Project life cycle and organization, covering why and how projects are initiated and pure project versus functional management; Scope management, covering the decision making process, scope creep versus progressive elaboration, and cost of change versus time; The planning phase, covering delivery methods and contract types, priorities, feasibility studies, and the “go” decision; Project budgeting, financing, and cost management, covering direct versus indirect cost, classes and purposes of estimates, bonds and insurance, and the CSI MasterFormat. …”
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software, multimedia -
2419
Isotopes as a Tool for Exploring Exoplanet Atmospheres
Published 2024“…While the search for signs of life has focused on terrestrial planets around M dwarf stars, an unambiguous detection of life—including through isotopologues—on a rocky world will likely remain out of reach in the JWST era. …”
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Thesis -
2420
inPhocus: current state and challenges of phage research in Singapore
Published 2022“…Topics were discussed relating to phage life cycles, diversity, the roles of phages in biofilms and the human gut microbiome, engineered phage lysins to combat polymicrobial infections in wounds, and the challenges and prospects of clinical phage therapy. …”
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Journal Article