Blood-stage malaria vaccine candidate RH5.1/Matrix-M in healthy Tanzanian adults and children; an open-label, non-randomised, first-in-human, single-centre, phase 1b trial by Silk, SE, Kalinga, WF, Salkeld, J, Mtaka, IM, Ahmed, S, Milando, F, Diouf, A, Bundi, CK, Balige, N, Hassan, O, Mkindi, CG, Rwezaula, S, Athumani, T, Mswata, S, Lilolime, NS, Simon, B, Msami, H, Mohamed, M, David, DM, Mohammed, L, Nyaulingo, G, Mwalimu, B, Juma, O, Mwamlima, TG, Sasamalo, IA, Mkumbange, RP, Kamage, JJ, Barrett, JR, King, LDW, Hou, MM, Pulido, D, Carnrot, C, Lawrie, AM, Cowan, RE, Nugent, FL, Roberts, R, Cho, J-S, Long, CA, Nielsen, CM, Miura, K, Draper, SJ, Olotu, AI, Minassian, AM

“…<p><strong>Background:</strong> A blood-stage Plasmodium falciparum malaria vaccine would provide a second line of defence to complement partially effective or waning immunity conferred by the approved pre-erythrocytic vaccines. …”

High p16 expression and heterozygous RB1 loss are biomarkers for CDK4/6 inhibitor resistance in ER+ breast cancer by Palafox, Marta, Monserrat, Laia, Bellet, Meritxell, Villacampa, Guillermo, Gonzalez-Perez, Abel, Oliveira, Mafalda, Brasó-Maristany, Fara, Ibrahimi, Nusaibah, Kannan, Srinivasaraghavan, Mina, Leonardo, Herrera-Abreu, Maria Teresa, Òdena, Andreu, Sánchez-Guixé, Mònica, Capelán, Marta, Azaro, Analía, Bruna, Alejandra, Rodríguez, Olga, Guzmán, Marta, Grueso, Judit, Viaplana, Cristina, Hernández, Javier, Su, Faye, Lin, Kui, Clarke, Robert B., Caldas, Carlos, Arribas, Joaquín, Michiels, Stefan, García-Sanz, Alicia, Turner, Nicholas C., Prat, Aleix, Nuciforo, Paolo, Dienstmann, Rodrigo, Verma, Chandra Shekhar, Lopez-Bigas, Nuria, Scaltriti, Maurizio, Arnedos, Monica, Saura, Cristina, Serra, Violeta

“…Here, we show that p16 overexpression is associated with reduced antitumor activity of CDK4/6 inhibitors in patient-derived xenografts (n = 37) and estrogen receptor-positive breast cancer cell lines, as well as reduced response of early and advanced breast cancer patients to CDK4/6 inhibitors (n = 89). …”
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Novel method of probe design for characterising unclassified microbial taxa in wastewater by Tan, Shi Ming

“…Shimingles; distinct clades were in line with two draft genomes recovered through genomic binning. …”
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InAlN/GaN high electron mobility transistors on Si for RF applications by Xing, Weichuan

“…Also, device geometries including gate length, line-to-space ratio of the nanostripchannel and gate-to-source distance have been studied. …”
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Effect of dopant solubility and excess doping on the superconducting properties of doped Nb3Sn prepared by field assisted sintering technique by Srivastava, N, Matthews, GAB, Liu, J, Speller, SC, Grovenor, CRM, Santra, S

“…The Y₂O₃&nbsp;particles was also considered as a possible cause of pinning down of grain boundaries in addition to NbO leading to grain refinement through Zener pinning. …”

Higher-order moments of the elliptic flow distribution in PbPb collisions at $$ \sqrt{s_{\textrm{NN}}} $$ = 5.02 TeV by Tumasyan, A., Adam, W., Andrejkovic, J. W., Bergauer, T., Chatterjee, S., Damanakis, K., Dragicevic, M., Escalante Del Valle, A., Hussain, P. S., Jeitler, M., Krammer, N., Lechner, L., Liko, D., Mikulec, I., Paulitsch, P., Pitters, F. M., Schieck, J., Schöfbeck, R., Schwarz, D., Sonawane, M., Templ, S., Waltenberger, W., Wulz, C.-E., Darwish, M. R., Janssen, T., Kello, T., Rejeb Sfar, H., Van Mechelen, P., Bols, E. S., D’Hondt, J., De Moor, A., Delcourt, M., El Faham, H., Lowette, S., Moortgat, S., Morton, A., Müller, D., Sahasransu, A. 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S., Zarubin, A., Zhizhin, I., Zhokin, A.

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Spintronics devices for neuromorphic computing by Tang, Shawn Zhen Kee

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“…A minimum current density is needed to overcome an intrinsic pinning to drive the helical DW, and the propagation along the nanowire is accompanied by a rotational motion. …”
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“…Furthermore, the analytical model also provides insights into the dynamics of skyrmion pinning and relaxation of asymmetric skyrmion pairs in bilayer-coupled skyrmion systems.…”
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“…This hysteresis is argued to arise from vortex depinning within a thin (< 20 nm) superconducting layer, mediated by discrete ferromagnetic dipoles located solely above the layer. The pinning strength may be modified by varying the superconducting channel thickness via electric field-effect doping. …”
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Multi-site benchmark classification of major depressive disorder using machine learning on cortical and subcortical measures by Belov, Vladimir, Erwin-Grabner, Tracy, Aghajani, Moji, Aleman, Andre, Amod, Alyssa R., Basgoze, Zeynep, Benedetti, Francesco, Besteher, Bianca, Bülow, Robin, Ching, Christopher R. K., Connolly, Colm G., Cullen, Kathryn, Davey, Christopher G., Dima, Danai, Dols, Annemiek, Evans, Jennifer W., Fu, Cynthia H. Y., Gonul, Ali Saffet, Gotlib, Ian H., Grabe, Hans J., Groenewold, Nynke, Hamilton, J. Paul, Harrison, Ben J., Ho, Tiffany C., Mwangi, Benson, Jaworska, Natalia, Jahanshad, Neda, Klimes-Dougan, Bonnie, Koopowitz, Sheri-Michelle, Lancaster, Thomas, Li, Meng, Linden, David E. J., MacMaster, Frank P., Mehler, David M. A., Melloni, Elisa, Mueller, Bryon A., Ojha, Amar, Oudega, Mardien L., Penninx, Brenda W. J. H., Poletti, Sara, Pomarol-Clotet, Edith, Portella, Maria J., Pozzi, Elena, Reneman, Liesbeth, Sacchet, Matthew D., Sämann, Philipp G., Schrantee, Anouk, Sim, Kang, Soares, Jair C., Stein, Dan J., Thomopoulos, Sophia I., Uyar-Demir, Aslihan, van der Wee, Nic J. A., van der Werff, Steven J. A., Völzke, Henry, Whittle, Sarah, Wittfeld, Katharina, Wright, Margaret J., Wu, Mon-Ju, Yang, Tony T., Zarate, Carlos, Veltman, Dick J., Schmaal, Lianne, Thompson, Paul M., Goya-Maldonado, Roberto

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Progressive collapse of reinforced concrete building structures by Dat, Pham Xuan

“…The associated rotationally-restrained but laterally-unrestrained boundary condition of the test specimens was effected by a set of pinned-end supporting columns. Uniformly distributed loads were simulated by a twelve-point loading system. …”
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Producing microscale Ge textures via titanium nitride- and nickel-assisted chemical etching with CMOS-compatibiliyty by Liao, Yikai, Shin, Sang-Ho, Jin, Yuhao, Wang, Qi Jie, Kim, Munho

“…Schottky contact barrier of metal catalyst with Ge is also investigated indicating similar hole injection efficiency among TiN, Ni, and Ti/Ni with Ge junction due to strong Fermi level pinning effect. The TiN- and Ni-assisted chemical etching of Ge shed light on CMOS-compatible Ge-based photonic and optoelectronic applications.…”
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Gettin’ sociolinguistic data remotely: comparing vernacularity during online remote versus in-person sociolinguistic interviews by Gardner, MH, Kostadinova, V

“…The goal of this research was to test whether a change in modality results in style-shifting, as quantified by different rates of formal/standard [-ɪŋ] versus informal/non-standard [-ɪn]. Results show that when the internal linguistic constraints governing (-ing) variation are taken into account, there is not a significant difference between modalities, suggesting both modalities are equally formal (or informal). …”

Additive friction stir processing by Lin, Longyi

“…The continuous dynamic recrystalisation during FSP also gave finer grains, which was further enhanced with the addition of CNTs through Zener pinning effect. The improvement in tensile strengths due to finer grains through the Hall-Petch mechanism was insufficient to compensate for the drop in Orowan strengthening. …”
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Influence of the exchange symmetry beyond the exclusion principle by Tennie, F

“…In particular, we <em>analytically</em> study the (quasi-)pinning effect which corresponds to a saturation of the GPCs and imposes structural simplifications on the <em>N</em>-fermion state. …”

Analysis and design of curved steel beam member in elevation using Eurocode 3 by Yandarmadi, Kelvin

“…This paper specifically focuses on analysing simply supported boundary condition curved beam member which pinned on the one end and roller that can be moved horizontally on the other end. …”
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A computerized template-driven news-layout system for newspapers. by Kan, Hsin-Kuo

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Software defined network : user centric network by Lim, Derrick Teck Leong.

“…A test of the application was done by running two continuous pings, one from each host to the other. Then, the path in use was disconnected. …”
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Challenges and applications to operando and in situ TEM imaging and spectroscopic capabilities in a cryogenic temperature range by Tyukalova, Elizaveta, Vas, Joseph Vimal, Ignatans, Reinis, Mueller, Aaron David, Medwal, Rohit, Imamura, Masaaki, Asada, Hironori, Fukuma, Yasuhiro, Rawat, Rajdeep Singh, Tileli, Vasiliki, Duchamp, Martial

“…Such studies are promising for studying the pinning of the ferroelectric and magnetic domains versus temperature, spin-polarized current, and externally applied magnetic field to better manipulate the domain walls. …”
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