Cognitive Effects of Simulated Galactic Cosmic Radiation Are Mediated by ApoE Status, Sex, and Environment in APP Knock-In Mice by Wieg, Laura, Ciola, Jason C., Wasén, Caroline C., Gaba, Fidelia, Colletti, Brianna R., Schroeder, Maren K., Hinshaw, Robert G., Ekwudo, Millicent N., Holtzman, David M., Saito, Takashi, Sasaguri, Hiroki, Saido, Takaomi C., Cox, Laura M., Lemere, Cynthia A.

“…Irradiated mice had immediate and long-term differences in their gut bacterial composition that correlated to Alzheimer’s disease phenotypes.…”
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Generative pretrained autoregressive transformer graph neural network applied to the analysis and discovery of novel proteins by Buehler, Markus J

“…</jats:p> <jats:p>Significance statement: Predicting the properties of materials based on a flexible description of their structure, environment, or process, is a long-standing challenge in multiscale modeling. Our MaterioFormer language model, trained to solve forward and inverse tasks, incorporates a deep learning capacity through attention and graph strategies to yield a multimodal approach to model and design materials. …”
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Discovering non-equilibrium mechanisms that regulatestructure and function of biomolecular condensates usingphase-field modeling by Natarajan, Pradeep

“…The second project investigates how transcription of messenger RNA (mRNA) by transcriptional condensates is modulated by other RNAs in the vicinity, such as long non-coding RNAs (lncRNAs). Our model reveals that lncRNA transcription in the vicinity can regulate mRNA transcription by altering the protein concentration and lifetime of transcriptional condensates, 3 promoting mRNA transcription from genes expressed at a low level and inhibiting transcription from highly expressed genes. …”
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Predicting Outcomes of Preterm Neonates Post Intraventricular Hemorrhage by Vignolle, Gabriel A., Bauerstätter, Priska, Schönthaler, Silvia, Nöhammer, Christa, Olischar, Monika, Berger, Angelika, Kasprian, Gregor, Langs, Georg, Vierlinger, Klemens, Goeral, Katharina

“…Intraventricular hemorrhage (IVH) in preterm neonates presents a high risk for developing posthemorrhagic ventricular dilatation (PHVD), a severe complication that can impact survival and long-term outcomes. Early detection of PHVD before clinical onset is crucial for optimizing therapeutic interventions and providing accurate parental counseling. …”
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Unexpected anthropogenic emission decreases explain recent atmospheric mercury concentration declines by Feinberg, Aryeh, Selin, Noelle E., Braban, Christine F., Chang, Kai-Lan, Custódio, Danilo, Jaffe, Daniel A., Kyllönen, Katriina, Landis, Matthew S., Leeson, Sarah R., Luke, Winston, Molepo, Koketso M., Murovec, Marijana, Nerentorp Mastromonaco, Michelle G., Aspmo Pfaffhuber, Katrine, Rüdiger, Julian, Sheu, Guey-Rong, St. Louis, Vincent L.

“…Anthropogenic activities emit ~2,000 Mg y−1 of the toxic pollutant mercury (Hg) into the atmosphere, leading to long-range transport and deposition to remote ecosystems. …”
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Mesoscale Brain Mapping: Bridging Scales and Modalities in Neuroimaging – A Symposium Review by Marchant, Joshua K., Ferris, Natalie G., Grass, Diana, Allen, Magdelena S., Gopalakrishnan, Vivek, Olchanyi, Mark, Sehgal, Devang, Sheft, Maxina, Strom, Amelia, Bilgic, Berkin, Edlow, Brian, Hillman, Elizabeth M. C., Juttukonda, Meher R., Lewis, Laura

“…“Mesoscale Brain Mapping: Bridging Scales and Modalities in Neuroimaging” brought together researchers who use a broad range of imaging techniques to study brain structure and function at the convergence of the microscopic and macroscopic scales. The day-long event centered on areas in which the CMM has established expertise, including the development of emerging technologies and their application to clinical translational needs and basic neuroscience questions. …”
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Multidose transient transfection of human embryonic kidney 293 cells modulates recombinant adeno‐associated virus2/5 Rep protein expression and influences the enrichment fraction o... by Srinivasan, Prasanna, Canova, Christopher T, Sha, Sha, Nguyen, Tam NT, Joseph, John, Sangerman, Jose, Maloney, Andrew J, Katsikis, Georgios, Ou, Rui Wen, Hong, Moo Sun, Ng, Jaclyn, Yuan, Arella, Antov, Daniel, Song, Sally, Chen, Wenyu, Neufeld, Caleb, Wolfrum, Jacqueline M, Barone, Paul W, Sinskey, Anthony J, Springs, Stacy L, Braatz, Richard D

“…Recombinant adeno-associated virus (rAAV) is a commonly used in vivo gene therapy vector because of its nonpathogenicity, long-term transgene expression, broad tropism, and ability to transduce both dividing and nondividing cells. …”
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Strain-specific parallel evolution drives short-term diversification during Pseudomonas aeruginosa biofilm formation by McElroy, Kerensa E., Hui, Janice G. K., Woo, Jerry K. K., Luk, Alison W. S., Webb, Jeremy S., Kjelleberg, Staffan, Rice, Scott A., Thomas, Torsten

“…Taken together, these results suggest that the majority of the P. aeruginosa genome is constrained by negative selection, with strong positive selection acting on an accessory subset of genes that facilitate adaptation to the biofilm lifecycle. Long-term bacterial evolution is known to proceed via few, nonsynonymous, positively selected mutations, and here we show that similar dynamics govern short-term, within-population bacterial diversification.…”
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A nonclassical monocyte phenotype in peripheral blood is associated with nonalcoholic fatty liver disease : a report from an EMIL subcohort by Wang, Yan, Oeztuerk, Suemeyra, Kratzer, Wolfgang, Boehm, Bernhard Otto

“…The nonclassical monocyte fraction and classical monocyte fraction were significantly correlated with waist-to-hip ratio. This pilot long-term follow-up study suggests that nonclassical monocyte fraction and total monocyte fraction might have potential as a prognostic and modifiable biomarker in NFALD patients. …”
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Laser-based 3D printing using bessel beams for tissue engineering applications by Liew, Andy Wen Loong

“…Scientists are also faced with the challenge of implant pre-vascularization which is deemed essential for long- term efficacy of the tissue construct post-implantation. …”
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Wind tunnel design and fabrication for lift force investigation by Ong, Jun Wei

“…Models are being mounted on sting balances, which is usually a long rod connected to the rear end of the model to prevent any disruption of airflow. …”
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Investigation of solar cell carrier lifetime using photoconductance lifetime measurements by Sng, Joseph Ding Wen

“…The results obtained show that among the three transition metal oxides, the Si wafer passivated with MoOx has the highest lifetime of 69.6 μs and lowest surface recombination velocity of 464.95 cm/s. The long lifetime achieved through the passivation is important for realizing good efficiency for the Si/TMO heterojunction solar cell. …”
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"中华胶不胶?" ：从媒体留言分析探讨马来西亚华人的对中立场 = Sinophobia or Sinophilia? Discussing the identity confusion among Malaysian Chinese : based on the comments analysis... by 李政辉 Lee, Chan Hui

“…The identity studies of Malaysian Chinese has been drawing the attention of the researchers for a long time, that a lot of studies have been conducted until recently. …”
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Structure-aware generation network for recipe generation from images by Wang, Hao, Lin, Guosheng, Hoi, Steven C. H., Miao, Chunyan

“…However, compared with image captioning datasets, the target recipes are long-length paragraphs and do not have annotations on structure information. …”
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Speeding up deep neural network training with decoupled and analytic learning by Zhuang, Huiping

“…Training deep neural networks usually demands a significantly long period of time. In this thesis, we explore methods in two different areas, i.e., decoupled learning and analytic learning, in order to reduce the training time. …”
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Chromosome-level genome assembly of the diploid blueberry Vaccinium darrowii provides insights into its subtropical adaptation and cuticle synthesis by Cui, Fuqiang, Ye, Xiaoxue, Li, Xiaoxiao, Yang, Yifan, Hu, Zhubing, Overmyer, Kirk, Brosché, Mikael, Yu, Hong, Salojärvi, Jarkko

“…Here, we assembled the V. darrowii genome into 12 pseudochromosomes using Oxford Nanopore long reads complemented with Hi-C scaffolding technologies, and we predicted 41 815 genes using RNA-sequencing evidence. …”
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Strong edge stress in molecularly thin organic-inorganic hybrid ruddlesden-popper perovskites and modulations of their edge electronic properties by Kripalani, Devesh Raju, Cai, Yongqing, Lou, Jun, Zhou, Kun

“…Organic-inorganic hybrid Ruddlesden-Popper perovskites (HRPPs) have gained much attention for optoelectronic applications due to their high moisture resistance, good processability under ambient conditions, and long functional lifetimes. Recent success in isolating molecularly thin hybrid perovskite nanosheets and their intriguing edge phenomena have raised the need for understanding the role of edges and the properties that dictate their fundamental behaviors. …”
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Ultrafast electronic relaxation dynamics of atomically thin MoS₂ is accelerated by wrinkling by Xu, Ce, Zhou, Guoqing, Alexeev, Evgeny M., Cadore, Alisson R., Paradisanos, Ioannis, Ott, Anna K., Soavi, Giancarlo, Tongay, Sefaattin, Cerullo, Giulio, Ferrari, Andrea C., Prezhdo, Oleg V., Loh, Zhi-Heng

“…Our study suggests that the sub-picosecond electronic relaxation dynamics of TMDs is amenable to strain engineering and that applications which require long-lived hot carriers, such as hot-electron-driven light harvesting and photocatalysis, should employ wrinkle-free TMDs.…”
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Geometry-mediated bridging drives nonadhesive stripe wound healing by Xu, Hongmei, Huo, Yucheng, Zhou, Quan, Wang, Abraham Lianghao, Cai, Pingqiang, Doss, Bryant, Huang, Changjin, Hsia, K. Jimmy

“…Here, we fabricate micropatterned hydrogel substrates with long, straight, and wavy non-cell-adhesive stripes of different gap widths to investigate the stripe edge curvature and stripe width effects on the reepithelialization of Madin-Darby canine kidney (MDCK) cells. …”
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Quantifying uncertainties in tropical cyclone wind hazard assessment due to synthetic track stochastic variability for Southeast Asia by Jian, Wei, Lo, Edmond Yat-Man, Stojanovski, Pane, Pan, Tso-Chien

“…Influence from other track parameters, such as TC size and forward speed, can become important for long exposure of TC trajectories. Such insights enable better understanding on the key drivers of sensitivities in the probabilistic hazard maps. …”
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