Environmental risk factors for self-harm during imprisonment: a prospective cohort study by Stephenson, T, Harris, I, Armstrong, C, Fazel, S, Short, R, Blackwood, N

“…Findings regarding staff-prisoner ratio and self-harm most likely reflect a reverse causal relationship. Replication in larger cohort studies is required to address the limitations of this pilot study.…”

The impact of social isolation on delayed hospital discharges of older hip fracture patients and associated costs by Landeiro, F, Leal, J, Gray, A

“…Patients who were admitted from an institution were less likely to have delayed discharges (OR 0.2) with 5.5 fewer days of delay. …”

A systematic analysis of the contribution of genetics to multimorbidity and comparisons with primary care data by Murrin, O, Mounier, N, Voller, B, Tata, L, Gallego-Moll, C, Roso-Llorach, A, Carrasco-Ribelles, LA, Fox, C, Allan, LM, Woodward, RM, Liang, X, Valderas, JM, Khalid, S, Dudbridge, F, Lamb, SE, Mancini, M, Farmer, L, Boddy, K, Bowden, J, Melzer, D, Frayling, TM, Masoli, JAH, Pilling, LC, Violán, C, Delgado, J

“…Discordance between genetic and primary care data was also observed, e.g., abdominal aortic aneurysm and bladder cancer co-occurred in primary care but were not genetically correlated (Odds-Ratio = 2.23 [2.09:2.37], 𝑅𝑔 = 0.04 [−0.20:0.28]) and schizophrenia and fibromyalgia were less likely to co-occur together in primary care but were positively genetically correlated (OR = 0.84 [0.75:0.94], 𝑅𝑔 = 0.20 [0.11:0.29]).…”

Cytisine versus varenicline for smoking cessation in a primary care setting: a randomized non-inferiority trial by Oreskovic, T, Percac-Lima, S, Ashburner, JM, Tiljak, H, Rifel, J, Klemenc Ketiš, Z, Oreskovic, S

“…Given the much lower cost of cytisine treatment, its lower rate of adverse events, and higher feasibility (but its likely lower effectiveness with the standard dosage regimen), future analyses should assess the cost-effectiveness of the two treatments for health policy considerations.…”

Assessment of novel pre-erythrocytic malaria vaccines in humans by Venkatraman, N

“…In addition to humoral immunity, it is widely recognised that T-cell mechanisms are likely to play an important role in malaria immunity and heterologous prime-boost regimes using viral-vectored vaccines have been shown to induce potent T-cell responses. …”

A mixed methods study investigating factors affecting adherence to Plasmodium vivax malaria primaquine radical cure regimens among migrants along the Myanmar-Thailand border by Ansari, AT, Aung, KK, Win, HH, Beau, C, Nu, B, Soe, NL, Htoo, K, San, T, Wah, TG, Keereevijit, A, Phyo, AP, Chotivanich, K, White, NJ, Nosten, F, Hashmi, AH, Chu, CS

“…Patients of Karen ethnicity (OR 1.7, 95% CI 1.2–2.3; p = 0.001) or having a previous episode of malaria from any species (OR 1.6, 95% CI 1.1–2.3; p = 0.007) were more likely to report completing the 14-day primaquine radical cure regimen. …”

Multi-species rotational grazing of small ruminants regenerates undergrowth vegetation while controlling weeds in the oil palm silvopastoral system by Tohiran, Kamil Azmi, Nobilly, Frisco, Zulkifli, Raja, Yahya, Muhammad Syafiq, Norhisham, Ahmad Razi, Rasyidi, Md Zainal, Azhar, Badrul

“…The use of single-species livestock grazing is likely to cause oil palm growers to use herbicides to control undesirable weeds. …”
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The level of knowledge, attitude and practice towards Covid-19 immunisation among medical students in public medical schools in Malaysia by Mohamad Zainal, Nurul Hayati, Mohammed Ayyub, Safiyya, Yi, Chang Fang, Zaman, Arif Najmi Shahrir, Mohd Nor, Nurul Huda, Omar, Norsuhana, Ku Mohd Noor, Ku Mastura, Hamimi Wahid, Hanan

“…Respondents in the age group of 21 to 24 years old (p < 0.001) and 25 to 29 years old (p = 0.016), and Indian ethnicity (p = 0.006) were more likely to have good knowledge. Respondents registered in Malaysia’s National COVID-19 vaccination program were considered as having a positive attitude (n = 264, 61.8). …”
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Evolutionary explanations and the debunking of moral beliefs by Cofnas, N

“…I argue that our innate moral faculty is likely not the product of natural selection, but rather social selection. …”

Vulnerability modeling, assessment, and improvement in urban metro systems: a probabilistic system dynamics approach by Chen, Hongyu, Chen, Bin, Zhang, Limao, Li, Hong Xian

“…The urban metro system is a complex system that is vulnerable to various kinds of hazards and subjected to dynamics, where errors in any part are very likely to cause system failures and accidents. A better understanding of evolutional dynamics of the system vulnerability over time enables to ensure the safety and security in its operation and provide guidance for long-term operation and maintenance for the metro system. …”
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Data-driven approach to spatiotemporal dynamic risk assessment of urban flooding based on shared socio-economic pathways by Wang, Mo, Chen, Furong, Zhang, Dongqing, Chen, Zijing, Su, Jin, Zhou, Shiqi, Li, Jianjun, Chen, Jintang, Li, Jiaying, Tan, Soon Keat

“…Under SSP126 scenario, nearly no change was predicted in the area with high flooding risk, with only increase of 1%, future urbanization hotspots associated with serious flooding risks will likely to be found on the fringe of the GBA's construction areas, in line with the extent of construction land expansion. …”
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Foot care behaviours and associated factors among patients with type 2 diabetes: a cross-sectional study by Ang, Chin-Siang, Goh, Kelley Fann Ing, Lodh, Nandika, Qin, Vicky Mengqi, Liew, Huiling, Sidhu, Harvinder Raj Singh, Ng, Jun Jie, Subramaniam, Tavintharan, Tan, Elaine, Koh, Gerald Choon Huat, Best, James, Wong, Julian, Car, Josip, Ho, Andy Hau Yan, Venkataraman, Kavita

“…The logistic regression analysis showed that current smokers were 60% less likely to practice good FC compared to non-smokers (odds ratio (OR) = 0.40; 95%; confidence interval (CI)= 0.22–0.73). …”
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Characterization and gene expression analysis of the cir multi-gene family of plasmodium chabaudi chabaudi (AS) by Lawton, Jennifer, Brugat, Thibaut, Yan, Yam Xue, Reid, Adam James, Böhme, Ulrike, Otto, Thomas Dan, Pain, Arnab, Jackson, Andrew, Berriman, Matthew, Cunningham, Deirdre, Preiser, Peter Rainer, Langhorne, Jean

“…Conclusions: In conclusion, the large number of cir genes and their expression throughout the intraerythrocytic cycle of development indicates that CIR proteins are likely to be important for parasite survival. In particular, the detection of dominant cir transcripts at the peak of P. chabaudi infection supports the idea that CIR proteins are expressed, and could perform important functions in the biology of this parasite. …”
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Molecular characterization of microbial interactions with labile dissolved organic matter by Halloran, Kathryn H.

“…This substrate selectivity is likely driven by transporter specificity. The distinct fate of these structurally similar molecules emphasizes the importance of compound-specific characterization of labile DOM. …”
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Exposure to Pb-halide perovskite nanoparticles can deliver bioavailable Pb but does not alter endogenous gut microbiota in zebrafish by Patsiou, Danae, del Rio-Cubilledo, Cristina, Catarino, Ana Isabel, Summers, Stephen, Afiq Mohd Fahmi, Boyle, David, Fernandes, Teresa F., Henry, Theodore B.

“…Exposure to Pb-halide perovskite NPs led to absorption of Pb likely from release of Pb ions rather than absorption of NPs. …”
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Poisson discretizations of Wiener functionals and Malliavin operators with Wasserstein estimates by Privault, Nicolas, Yam, Phillip S. C., Zhang, Zheng

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A bilayer swellable drug-eluting stent for the treatment of fibrosis-induced ureteral stricture recurrence by Lim, Wei Shan

“…These observations were likely due to the high equilibrium water content hence promoting the drug release. …”
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Strategies to increase response rate and reduce non-response bias in population health research: a series of randomised controlled trials during a large COVID-19 study by Atchison, CJ, Gilby, N, Pantelidou, G, Clemens, S, Pickering, K, Chadeau-Hyam, M, Ashby, D, Barclay, WS, Cooke, G, Darzi, A, Riley, S, Donnelly, C, Ward, H, Elliott, P

“…Those receiving an additional text message were more likely to return a completed swab compared to those receiving the standard approach, 73.3% v 70.2%: percentage difference 3.1% (95% CI 2.2%, 4.0%).…”

The relationship between leisure time physical activity patterns, Alzheimer’s disease markers and cognition by James, S, Sudre, CH, Barnes, J, Cash, DM, Chiou, Y, Coath, W, Keshavan, A, Lu, K, Malone, I, Murray-Smith, H, Nicholas, JM, Orini, M, Parker, T, Almeida-Meza, P, Fox, NC, Richards, M, Schott, JM

“…Engagement in leisure time physical activity in the life course is associated with better cognitive functioning at age 70, even in those with early markers of Alzheimer’s disease. If causal, this is likely via multiple pathways, potentially through the preservation of hippocampal volume, as well as via cognitive resilience pathways delaying cognitive manifestations of early markers of Alzheimer’s disease, particularly in women. …”

Adverse health events associated with antipsychotic use: an umbrella review by Chow, RTS

“…In terms of patient variables, older adults aged over 65 and patients with dementia were more likely to experience antipsychotic-associated adverse outcomes than adults and patients with schizophrenia. …”