Immunogenic recombinant Mayaro virus-like particles present natively assembled glycoprotein by Kim, YC, Watanabe, Y, Arlen-Celina, L, Song, X, de Oliveira Souza, R, Stass, R, Azar, SR, Rossi, SL, Claser, C, Kümmerer, BM, Crispin, M, Bowden, TA, Huiskonen, JT, Reyes-Sandoval, A

“…Immunisation of Mayaro virus VLPs in mice with or without an adjuvant (poly:IC) yielded similar levels of neutralising antibodies suggesting that the VLPs may be used for immunisation without the need for an adjuvant. …”

Intraperitoneal administration of mRNA encoding interleukin-12 for immunotherapy in peritoneal carcinomatosis by Arrizabalaga, L, Di Trani, CA, Fernández-Sendin, M, Bella, Á, Russo-Cabrera, JS, Gomar, C, Ardaiz, N, Belsue, V, González-Gomariz, J, Zalba, S, Gil-Korilis, A, Garrido, MJ, Melero, I, Aranda, F, Berraondo, P

“…To explore the therapeutic potential of this approach, mRNA complexes encoding single-chain interleukin-12 (IL12), an immunostimulatory molecule (mRNA-IL12), were investigated. mRNA-IL12-treated mice exhibited a significant survival advantage in models of peritoneal carcinomatosis and acquired immune memory, as shown upon subcutaneous rechallenge. …”

新加坡华人英语、华语语码转换策略的研究 = A study of code-switching strategy of English and Chinese in the Singapore Chinese community by 王晓梅 Wang, Xiao Mei

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Why is China in Africa? by Neo, Jackson Jie Sheng

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Automatic trajectory generation for free-form pocket machining in skull base surgery by Lo, Charles Vui Hong.

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儒家的异端 ： 试析李贽思想与儒家学说的共通点 = An analysis of the similarity between Lizhi’s thoughts and Confucianism by 刘佑勋 Liew, Youxun

“…However, it is to be noted that under the context of the “Union of the Three Religions”（三教合一）, namely Confucianism, Buddhism and Daoism, in the Ming dynasty, such association can be said to be a natural result of the societal trend. …”
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China's engagement with the liberal international order by Chua, Ze Ping

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Loss of Caᵥ1.3 RNA editing enhances mouse hippocampal plasticity, learning, and memory by Zhai, Jing, Navakkode, Sheeja, Yeow, Sean Qing Zhang, Krishna-K, Kumar, Liang, Mui Cheng, Koh, Joanne Huifen, Wong, Rui Xiong, Yu, Wei Ping, Sajikumar, Sreedharan, Huang, Hua, Soong, Tuck Wah

“…Here, by genetic targeting to ablate CaV1.3 RNA editing, we demonstrate that unedited CaV1.3ΔECS mice exhibited improved learning and enhanced long-term memory, supporting a functional role of RNA editing in behavior. …”
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Wear behaviour of NiTi shape memory alloys by Yan, Lina

“…For example, since mechanical properties of NiTi SMAs are close to those of cortical bones, NiTi SMA based implants such as joint replacements, bone plates, and spine fracture fixations were developed. However, complex wear modes on the surface may cause undesired reactions from neighboring tissues, leading to a serious inflammation of the human body. …”
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DEEP-squared: deep learning powered De-scattering with Excitation Patterning by Wijethilake, Navodini, Anandakumar, Mithunjha, Zheng, Cheng, So, Peter T. C., Yildirim, Murat, Wadduwage, Dushan N.

“…We demonstrate our method in multiple numerical and experimental imaging studies, including in vivo cortical vasculature imaging up to 4 scattering lengths deep in live mice.…”
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Identification of a humanized mouse model for functional testing of immune-mediated biomaterial foreign body response by Doloff, Joshua C, Ma, Minglin, Sadraei, Atieh, Tam, Hok Hei, Farah, Shady, Hollister-Lock, Jennifer, Vegas, Arturo J, Veiseh, Omid, Quiroz, Victor M, Rakoski, Amanda, Aresta-DaSilva, Stephanie, Bader, Andrew R, Griffin, Marissa, Weir, Gordon C, Brehm, Michael A, Shultz, Leonard D, Langer, Robert, Greiner, Dale L, Anderson, Daniel G

“…Foreign body giant cell formation, often unobserved in mice, was also prominent. Last, high-resolution microscopy coupled with multiplexed antibody capture digital profiling analysis supplied spatial resolution of rejection responses. …”
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CD1d‐mediated lipid presentation by CD11c+ cells regulates intestinal homeostasis by Sáez de Guinoa, Julia, Jimeno, Rebeca, Gaya, Mauro, Kipling, David, Garzón, María J., Dunn‐Walters, Deborah, Ubeda, Carles, Barral, Patricia

“…These changes in intestinal homeostasis require CD1d expression on DC/macrophage populations as mice with conditional deletion of CD1d on CD11c+ cells exhibit dysbiosis and altered immune homeostasis. …”
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Mechanisms that promote the evolution of cross-reactive antibodies upon vaccination with designed influenza immunogens by Yang, Leerang, Caradonna, Timothy M, Schmidt, Aaron G, Chakraborty, Arup K

“…Here, we develop a computational model to interrogate antibody evolution by affinity maturation after immunization with two types of immunogens: a heterotrimeric "chimera" hemagglutinin that is enriched for the RBS epitope relative to other B cell epitopes and a cocktail composed of three non-epitope-enriched homotrimers of the monomers that comprise the chimera. Experiments in mice find that the chimera outperforms the cocktail for eliciting RBS-directed antibodies. …”
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Biomimetic nanocomposites to control osteogenic differentiation of human mesenchymal stem cells by Liao, Susan, Nguyen, Luong T. H., Ngiam, Michelle, Wang, Charlene, Cheng, Ziyuan, Chan, Casey K., Ramakrishna, Seeram

“…When subcutaneously implanted into nude mice, this biomimetic nanocomposite is able to form a new bone matrix within only two weeks. …”
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Protocol to study dam-pup social transmission using a modified paradigm for transmission of food preference by Ham, Gao Xiang, Ong, Jonathan Z., Augustine, George James, Leong, Victoria

“…We describe steps for studying weanling mice from the same mother and present a worked example using weight-based (food consumption) and time-based (exploration) indices of social learning.…”
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Investigating the human teashirt genes TSHZ2 and TSHZ3 in pancreatic and endocrine lineage commitment using genome modified human embryonic stem cells (hESC) by Eng, Shermaine Zi Hui

“…Loss of PDX1 results in complete pancreatic agenesis in both mice and man, indicating that it is a master regulator that coordinates the morphogenesis of this indispensable organ. …”
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Comparison of CRISPR-Cas13b RNA base editing approaches for USH2A-associated inherited retinal degeneration by Fry, LE, Major, L, Salman, A, McDermott, LA, Yang, J, King, AJ, McClements, ME, MacLaren, RE

“…Mean RNA editing rates in photoreceptors across different constructs ranged from 0.32% to 2.04%, with greater efficiency in those injected with PspCas13b compared to Cas13bt3 constructs. In mice injected with PspCas13b constructs, usherin protein was successfully restored and correctly localized to the connecting cilium following RNA editing. …”

A local product-of-exponentials method for the kinematic calibration of modular reconfigurable robots by Tan, Chee Tat.

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Analysis of path planning method using artificial potential field in complex urban environment for UAV by Fong, Marcus Kang Jie

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The ethics of dark comedy by Lee, Hanna

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