Dose escalation pre-clinical trial of novel DOK7-AAV in mouse model of DOK7 congenital myasthenia by Cossins, J, Kozma, I, Canzonetta, C, Hawkins, A, Beeson, D, Sepulveda, P, Dong, YY

“…EMG showed that the treated model mice had decrement of compound muscle action potential on repetitive nerve stimulation, which indicates defective signalling at the neuromuscular junction. …”

Identification and application of self-binding zipper-like sequences in SARS-CoV spike protein by Zhang, Si Min, Liao, Ying, Neo, Tuan Ling, Lu, Yanning, Liu, Ding Xiang, Vahlne, Anders, Tam, James Pingkwan

“…Self-binding peptides containing zipper-like sequences, such as the Leu/Ile zipper sequence within the coiled coil regions of proteins and the cross-β spine steric zippers within the amyloid-like fibrils, could bind to the protein-of-origin through homophilic sequence-specific zipper motifs. …”
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Hearing loss and risk of major osteoporotic fracture: a population-based cohort study in the United Kingdom by Khalid, S, Alhambra, DP, Hasheminasab, SA, Vinogradova, Y, Qureshi, N, Ratzinger, M, Brunetti, V, Salas, A, Canals, L

“…Purpose: Assess association between hearing loss (HL) and major osteoporotic fracture (MOF; spine, wrist/forearm, shoulder/proximal humerus, hip) in individuals aged ≥ 60 years, and risk factors for MOF in individuals with HL. …”

The role of post-pyrolysis carbon dioxide capture in hydrogen recovery from waste-derived pyrolysis gas by Wang, Yuxin, Veksha, Andrei, Ong, Joel, Ueki, Yasuaki, Yoshiie, Ryo, Naruse, Ichiro, Lisak, Grzegorz

“…The pyrolysis gas was obtained from various waste-derived feedstocks (municipal sewage sludge, refused derived fuel (RDF), pine sawdust (biomass), and marine litter) by pyrolysis (600 °C), and underwent the treatment with CaO (600 °C) followed by the thermolytic decomposition at 1300 °C. …”
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Automated teller machines in Singapore by Soh, Yong Chee, Phua, Alice Loo Huay, Tan,Yang Leng

“…Activation of ATMs can also be enhanced by substituting the present A TM card and PIN system with either voice recognition, retina recognition or thumbprints. …”
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Real time analysis of social behavior from video and kinect recordings by Ramasamy, Pandi Ramesh

“…Finally,analysis will be performed using pattern recognition algorithms and machine learning classifiers to detect the emotion of the subject.In this project,machine learning classifiers such as K-nearest neighbors,Naive Bayes and C4.5 Decision tree learning has been used. The prime aim is to pin point the most seemly machine learning classifier for obtaining highest accuracy for classification.…”
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Virtual-real-fusion simulation framework for evaluating and optimizing small-spatial-scale placement of cooperative roadside sensing units by Ma, Yang, Zheng, Yubing, Wang, Shuyi, Wong, Yiik Diew, Easa, Said M.

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Local release of rapamycin by microparticles delays islet rejection within the anterior chamber of the eye by Fan, Yanliang, Zheng, Xiaofeng, Berggren, Per-Olof, Loo, Joachim Say Chye, Yusuf Ali

“…Here, we show that islet rejection in the ACE of mice can be significantly suppressed through local delivery of rapamycin by carefully designed sustained-release microparticles. …”
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Inhibition of endoplasmic reticulum stress using 4-phenyl butyrate mitigates osteoporosis in a mouse model of hindlimb suspension by Al-Daghestani, Hiba Saad Subhi

“…HLS duration was for 21 days, thereafter, mice were euthanized by cervical dislocation. Humeri, femora, and tibiae bones were collected and cleaned from soft tissues for measurements of reactive oxygen species (ROS) levels, histomorphometry, micro-CT, Raman spectroscopy, and gene expression studies. …”
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The inference-boundary model reinterpreting theme and rheme by Leong, Ping Alvin

“…The Hallidayan notions of theme and rheme pose an interesting challenge to linguists in their attempts to pin them down more specifically. This paper argues that since the thematic structure of the clause organises it as a message, a useful starting point in theme–rheme research is an understanding of how clausal messages are typically processed by language users. …”
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The effects of processing conditions on the morphology of single conjugated polymers. by Yeo, Hui Lin.

“…Drop-cast single chains were proposed to either retain its extended conformation in CHCl3 solution, or adopt an ordered structure with hair-pin loops, giving rise to two corresponding distinct types of intensity traces. …”
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Experimental and numerical study of self-locking adaptable inter connection for modular steel structures by Nadeem, Gohar, Safiee, Nor Azizi, Bakar, Nabilah Abu, Karim, Izian Abd, Mohd Nasir, Noor Azline

“…The findings indicated that the gap produced between connection and column under higher displacement was sensitive to the outer bolt and spring pin. This gap could be further reduced by increasing the number of outer bolts and by reducing tolerance between adapter and column walls.…”

Smart home control system design using internet of things based energy harvesting technology by Silalahi, Lukman Medriavin, Indrawan, Muhammad Rafi, Budiyanto, Setiyo, Hanafi, Dirman, Abdul Hamid, Abdul Hamid, Ronaldo, Davit

“…The objective of this research is to provide security for homeowners by facilitating fingerprints and PIN (Personal Identification Numbers) in entering the house, then in the event of a power outage, it activates the function of energy harvesting technology. …”
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Investigation of low temperature wafer bonding using intermediate layer by Deng, Shusheng

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幽禁中之丰姿，落寞中之妖冶：《唐詩名媛集》述評 = Charming in silence and coquettish in desolate : a commentary on Tangshi Mingyuan Ji by 曲景毅 Qu, Jingyi

“…Tangshi mingyuan ji 唐詩名媛集 (A compilation of Tang poems on mingyuan) is one of the volumes of Tangshi yanyi pin 唐詩艷逸品 (Exemplars of the flamboyant and the elegant in Tang poetry) edited by late Ming scholar Yang Zhaozhi 楊肇祉. …”
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Correlates of coping strategies on help-seeking behaviour by Tee, Poh Yean.

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论致良知的公共伦理意涵 = Analysis of the value of Zhi Liang Zhi as public ethics by 吴建璋 Oh, Jian Zhang

“…Wang Shouren (1472-1529), more commonly known as Wang Yangming, is an established Neo-Confucian Scholar during the Ming Dynasty. He developed his Zhi Liang Zhi （致良知）approach during his late years in 1521. …”
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High-efficiency magnetophoretic labelling of adoptively-transferred T cells for longitudinal in vivo magnetic particle imaging by Tay, Rong En, Lokamitra, P., Pang, Shun Toll, Low, Kay En, Tay, Hui Chien, Ho, Charmaine Min, Malleret, Benoit, Rötzschke, Olaf, Olivo, Malini, Tay, Zhi Wei

“…Methods: A high-efficiency magnetophoretic method was developed for facile magnetic labelling of hard-to-label immune cells, which were then injected into tumour-bearing mice and imaged over two weeks with a compact benchtop Magnetic Particle Imager (MPI) design. …”
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Negative auto-regulation of myostatin expression is mediated by SMAD3 and microRNA-27 by Ge, XiaoJia, McFarlane, Craig, Vajjala, Anuradha, Arigela, Harikumar, Lokireddy, Sudarsanareddy, Bonala, Sabeera, Manickam, Ravikumar, Kambadur, Ravi, Sharma, Mridula

“…Sequence analysis of Mstn 3′ UTR showed a single highly conserved miR-27a/b binding site and increased expression of miR-27a/b was correlated with decreased expression of Mstn and vice versa both in vitro and in mice in vivo. Moreover, we also show that Mstn gene expression was regulated by miR-27a/b. …”
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Role of the collagen receptor DDR1 in epithelial morphogenesis and polarisation by Søgaard, P

“…</p> <p>The role of DDR1 in epithelial organisation was reflected in the epithelium of the mammary gland of lactating DDR1-null mice, which had smaller alveoli with a diffuse distribution of basement membrane components compared to wild type mice. …”