A two-dimensional co-rotational Timoshenko beam element with XFEM formulation by Xu, Jin, Lee, Chi King, Tan, Kang Hai

“…Pin connections and plastic hinges produce non-smooth displacement fields in beam structures. …”
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Hippocampal transcriptome profiling reveals common disease pathways in chronic hypoperfusion and aging by Baik, Sang-Ha, Selvaraji, Sharmelee, Fann, David Y., Poh, Luting, Jo, Dong-Gyu, Herr, Deron R., Zhang, Shenpeng R., Kim, Hyun Ah, Silva, Michael De, Lai, Mitchell K. P., Chen, Christopher Li- Hsian, Drummond, Grant R., Lim, Kah-Leong, Sobey, Christopher G., Arumugam, Thiruma V.

“…However, BCAS-induced changes in hippocampal gene expression differed between young and aged mice. Specifically, transcriptomic analysis indicated that in comparison to young sham mice, many pathways altered by BCAS in young mice resembled those already present in sham aged mice. …”
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Evaluation of the Digital Ventilated Cage® system for circadian phenotyping by Tir, S, Foster, RG, Peirson, SN

“…Home cage activity in C57BL/6J mice was recorded under a range of lighting conditions, along with circadian clock-deficient cryptochrome-deficient mice (Cry1−/−, Cry2−/− double knockout). …”

Study of heat transfer through micro-structured surfaces by Chin, Wei Hao

“…Each chip has a different microstructure in the form of very small and elongated pin-fins, which will in turn affect the critical heat flux of each component. …”
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CubeSat deformable mirror demonstration by Cahoy, K., Marinan, A., Kerr, C., Cheng, K., Jamil, S.

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Discovery of COVID-19 protein inhibitors in phenolic acids of azadirachta indica (neem) using docking and pharmacokinetics by Roney, Miah, Huq, AKM Moyeenul, Mohd Fadhlizil Fasihi, Mohd Aluwi

“…The most attractive antiviral targets of SARS-CoV-2 are the spike protein and main protease (Mpro). In this work, sixteen phenolic acids of Azadirachta indica were docked into the active site of the spike protein and Mpro. …”
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B cell receptor repertoire kinetics after SARS-CoV-2 infection and vaccination by Kotagiri, P, Mescia, F, Rae, WM, Bergamaschi, L, Tuong, ZK, Turner, L, Hunter, K, Gerber, PP, Hosmillo, M, Hess, C, Clatworthy, MR, Goodfellow, IG, Matheson, NJ, McKinney, EF, Wills, MR, Gupta, RK, Bradley, JR, Bashford-Rogers, RJM, Lyons, PA, Smith, KGC

“…Infection generates a broad distribution of SARS-CoV-2-specific clones predicted to target the spike protein, while a more focused response after vaccination mainly targets the spike's receptor-binding domain. …”

Implementation and validation of a CubeSat laser transmitter by Kingsbury, R. W., Caplan, D. O., Cahoy, K. L.

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Metronidazole causes skeletal muscle atrophy and modulates muscle chronometabolism by Manickam, Ravikumar, Oh, Hui Yun Penny, Tan, Chek Kun, Paramalingam, Eeswari, Wahli, Walter

“…Furthermore, metronidazole in SPF mice decreases hind limb muscle weight and results in smaller fibers in the tibialis anterior muscle. …”
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Ultracompact high-sensitivity biosensing based on regenerable laminated bio-conjugation in integrated photonic circuits by Li, Z. Y., Chen, Y. Y., Xiong, S., Truc, N. K., Xiong, Q. H., Liu, Ai Qun

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Obesity-driven reprogramming of lung macrophages by Pohan, Clarice

“…Upon further investigation, we found that AMs from high-fat diet fed obese (>30wks) mice had larger lipid droplets than those from young lean (<12wks) and age-matched lean (>30wks) mice. …”
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PIERCE1: a determinant of left-right asymmetry in mammals by Farley, H

“…<p>The study of mice with heart and situs defects can provide useful models for improving our understanding of congenital heart defects in humans. …”

Cortical regulation of sleep by Krone, LB

“…First, I present laminar recordings of neocortical activity during sleep in wild type mice, which suggest that layer 5 actively drives slow waves. …”

Multiplexed CRISPR/CAS9‐mediated engineering of pre‐clinical mouse models bearing native human B cell receptors by Wang, Xuesong, Ray, Rashmi, Kratochvil, Sven, Melzi, Eleonora, Lin, Ying‐Cing, Giguere, Sophie, Xu, Liling, Warner, John, Cheon, Diane, Liguori, Alessia, Groschel, Bettina, Phelps, Nicole

“…KI mice expressing functional human BCRs promise to accelerate the development of vaccines for HIV and other infectious diseases.…”
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Blimp-1 and c-Maf regulate immune gene networks to protect against distinct pathways of pathobiont-induced colitis by Alvarez-Martinez, M, Cox, LS, Pearson, CF, Branchett, WJ, Chakravarty, P, Wu, X, Slawinski, H, Al-Dibouni, A, Samelis, VA, Gabryšová, L, Priestnall, SL, Suárez-Bonnet, A, Mikolajczak, A, Briscoe, J, Powrie, F, O'Garra, A

“…Double-deficient Prdm1^fl/flMaf^fl/flCd4^Cre mice infected with Helicobacter hepaticus developed severe colitis with an increase in T_H1/NK/ILC1 effector genes in LPLs, while Prdm1^fl/flCd4^Cre and Maf^fl/flCd4^Cre mice exhibited moderate pathology and a less-marked type 1 effector response. …”

Design of wideband low-loss reconfigurable reflectarray antenna by Zhang, Xiran

“…It proposes an RRA design that integrates a PIN diode with air gap. The switch of the reconfigurable unit is directly mounted on the reflective element, reducing the loss introduced by the switching device. …”
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Influence of operating parameters on morphology of laser hardened surfaces by Maharjan, Niroj, Zhou, Wei, Zhou, Yu, Wu, Naien

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Development of optical transceiver by Sim, Sebastian Shih Wei.

“…For PIN photodiodes, the epitaxial layer was introduced to the structures to act as an intrinsic layer. …”
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Improved margin multi-class classification using dendritic neurons with morphological learning by Hussain, Shaista, Liu, Shih-Chii, Basu, Arindam

“…We present an architecture of a spike based multiclass classifier using neurons with non-linear dendrites and sparse synaptic connectivity where each synapse takes a binary value. …”
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Identification and characterisation of the haematopoietic stem/progenitor cells at risk for leukaemia development following radiation exposure by Verbiest, T

“…Finally, we report on a gender-dependent leukaemic progression and characterisation where 3 Gy irradiated male mice only present with acute myeloid leukemia and irradiated female mice mainly develop leukaemia with a lymphoid phenotype. …”