Metronidazole causes skeletal muscle atrophy and modulates muscle chronometabolism by Manickam, Ravikumar, Oh, Hui Yun Penny, Tan, Chek Kun, Paramalingam, Eeswari, Wahli, Walter

“…Furthermore, metronidazole in SPF mice decreases hind limb muscle weight and results in smaller fibers in the tibialis anterior muscle. …”
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Obesity-driven reprogramming of lung macrophages by Pohan, Clarice

“…Upon further investigation, we found that AMs from high-fat diet fed obese (>30wks) mice had larger lipid droplets than those from young lean (<12wks) and age-matched lean (>30wks) mice. …”
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PIERCE1: a determinant of left-right asymmetry in mammals by Farley, H

“…<p>The study of mice with heart and situs defects can provide useful models for improving our understanding of congenital heart defects in humans. …”

Cortical regulation of sleep by Krone, LB

“…First, I present laminar recordings of neocortical activity during sleep in wild type mice, which suggest that layer 5 actively drives slow waves. …”

Multiplexed CRISPR/CAS9‐mediated engineering of pre‐clinical mouse models bearing native human B cell receptors by Wang, Xuesong, Ray, Rashmi, Kratochvil, Sven, Melzi, Eleonora, Lin, Ying‐Cing, Giguere, Sophie, Xu, Liling, Warner, John, Cheon, Diane, Liguori, Alessia, Groschel, Bettina, Phelps, Nicole

“…KI mice expressing functional human BCRs promise to accelerate the development of vaccines for HIV and other infectious diseases.…”
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Blimp-1 and c-Maf regulate immune gene networks to protect against distinct pathways of pathobiont-induced colitis by Alvarez-Martinez, M, Cox, LS, Pearson, CF, Branchett, WJ, Chakravarty, P, Wu, X, Slawinski, H, Al-Dibouni, A, Samelis, VA, Gabryšová, L, Priestnall, SL, Suárez-Bonnet, A, Mikolajczak, A, Briscoe, J, Powrie, F, O'Garra, A

“…Double-deficient Prdm1^fl/flMaf^fl/flCd4^Cre mice infected with Helicobacter hepaticus developed severe colitis with an increase in T_H1/NK/ILC1 effector genes in LPLs, while Prdm1^fl/flCd4^Cre and Maf^fl/flCd4^Cre mice exhibited moderate pathology and a less-marked type 1 effector response. …”

Design of wideband low-loss reconfigurable reflectarray antenna by Zhang, Xiran

“…It proposes an RRA design that integrates a PIN diode with air gap. The switch of the reconfigurable unit is directly mounted on the reflective element, reducing the loss introduced by the switching device. …”
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Development of optical transceiver by Sim, Sebastian Shih Wei.

“…For PIN photodiodes, the epitaxial layer was introduced to the structures to act as an intrinsic layer. …”
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Improved margin multi-class classification using dendritic neurons with morphological learning by Hussain, Shaista, Liu, Shih-Chii, Basu, Arindam

“…We present an architecture of a spike based multiclass classifier using neurons with non-linear dendrites and sparse synaptic connectivity where each synapse takes a binary value. …”
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Identification and characterisation of the haematopoietic stem/progenitor cells at risk for leukaemia development following radiation exposure by Verbiest, T

“…Finally, we report on a gender-dependent leukaemic progression and characterisation where 3 Gy irradiated male mice only present with acute myeloid leukemia and irradiated female mice mainly develop leukaemia with a lymphoid phenotype. …”

Environmental enrichment preconditioning prevents chronic social defeat stress-induced memory impairment and hippocampal neurodegeneration by Nik Ramli, Nik Nasihah, Shamsul Adzmi, Nur Adzreen, Nasarudin, Siti Nur Atiqah Zulaikah, Hashim, Mohamad Hisham

“…However, there is a paucity of studies examining the effects of environmental enrichment on learning and memory in chronic social defeat stress (CSDS) models. Male C57BL/6N mice were (n=5) housed in enriched environments for 30 days before undergoing daily social defeat stress by ICR strain aggressor mice over 10 days. …”
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Optimized core design of a supercritical carbon dioxide-cooled fast reactor by Handwerk, Christopher S. (Christopher Stanley), 1974-

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Time-restricted feeding modulates the DNA methylation landscape, attenuates hallmark neuropathology and cognitive impairment in a mouse model of vascular dementia by Selvaraji, Sharmelee, Efthymios, Motakis, Foo, Roger Sik Yin, Fann, David Y., Lai, Mitchell Kim Peng, Chen, Christopher Li Hsian, Lim, Kah-Leong, Arumugam, Thiruma V.

“…Modulation of DNA methylation patterns in the cortex of AL CCH mice was re-modelled and signs of reversal was observed in IF CCH mice across all three timepoints. …”
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Homocysteine metabolism pathway is involved in the control of glucose homeostasis: a cystathionine beta synthase deficiency study in mouse by Cruciani-Guglielmacci, Céline, Meneyrol, Kelly, Denom, Jessica, Kassis, Nadim, Rachdi, Latif, Makaci, Fatna, Migrenne-Li, Stéphanie, Daubigney, Fabrice, Georgiadou, Eleni, Denis, Raphaël G., Sanchez-Archidona, Ana Rodriguez, Paul, Jean-Louis, Thorens, Bernard, Rutter, Guy A., Magnan, Christophe, Le Stunff, Hervé, Janel, Nathalie

“…We evidenced a defect in the stimulated insulin secretion in CBS+/- mice with mild and intermediate HHcy, while mice with intermediate HHcy under HFD presented an improvement in insulin sensitivity that compensated for the decreased insulin secretion and permitted them to maintain a glucose tolerance similar to the CBS+/+ mice. …”
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Characterizing the function of the Arl15 gene and its role in the development of metabolic traits by Bai, Y

“…</p> <p>CRISPR/Cas9 germline knockout of Arl15 showed that homozygous KO mice die postnatally due to a complete cleft palate while heterozygous KO female mice have reduced fat mass on a normal diet. …”

Seroprevalence of SARS-CoV-2 in children and adolescents by Ratcliffe, H

“…The results showed a high prevalence of pre-existing immunity against seasonal coronaviruses when measuring IgG concentration of antibodies against spike protein but did not confer protection against SARS-CoV-2.…”

Numerical modelling of detonation reaction zone of nitromethane by EXPLO5 code and wood and kirkwood theory by Štimac, Barbara, Chan, Serene Hay Yee, Kunzel, Martin, Muhamed Suceska

“…The measured particle velocity profile of NM shows the existence of a sharp spike followed by a rapid drop over the first 5-10 ns (fast reaction). …”
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Telomere oxidation status (TOS) is correlated with relative telomere length (RTL) across different mouse tissues but not with nicotinamide nucleotide transhydrogenase (Nnt) status by Kidd, Elliot, Meimaridou, Eirini, Walley, Andrew, Fairbrother, Una

“…We investigated whether Nnt deficient mice have reduced TL and display markers of TOS compared to WT and rescued mice and whether this was tissue specific.…”
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Automatic test chip set by Chin, Edward Hsi Ling.

“…In this project, the fundamental functions and basic circuitry of an universal pin electronics are investigated and designed.…”
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Modeling distance-dependent individual head-related transfer functions in the horizontal plane using frontal projection headphones by Sunder, Kaushik, Gan, Woon-Seng, Tan, Ee-Leng

“…Soc. 61, 989–1000] project the sound directly onto the pinnae from the front, and thus inherently create listener's idiosyncratic pinna cues at the eardrum. …”
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