SARS-CoV-2 evolution during treatment of chronic infection by Kemp, SA, Collier, DA, Datir, RP, Ferreira, IATM, Gayed, S, Jahun, A, Hosmillo, M, Rees-Spear, C, Mlcochova, P, Lumb, IU, Roberts, DJ, Chandra, A, Temperton, N, Sharrocks, K, Blane, E, Modis, Y, Leigh, KE, Briggs, JAG, van Gils, MJ, Smith, KGC, Bradley, JR, Smith, C, Doffinger, R, Ceron-Gutierrez, L, Barcenas-Morales, G, Pollock, DD, Goldstein, RA, Smielewska, A, Skittrall, JP, Gouliouris, T, Goodfellow, IG, Gkrania-Klotsas, E, Illingworth, CJR, McCoy, LE, Gupta, RK

“…The spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is critical for virus infection through the engagement of the human ACE2 protein1 and is a major antibody target. …”

Investigating the role of factor inhibiting HIF (FIH) in tumourigenesis by Ma, J

“…</p> <p>By monitoring the spontaneous tumour formation in mice, it was found that a lack of FIH expression does not profoundly affect the lifespan but accelerates the development of low-grade B cell lymphomas. …”

Enhancing antibody responses by multivalent antigen display on thymus-independent DNA origami scaffolds by Wamhoff, Eike-Christian, Ronsard, Larance, Feldman, Jared, Knappe, Grant A., Hauser, Blake M., Romanov, Anna, Case, James Brett, Sanapala, Shilpa, Lam, Evan C., Denis, Kerri J. St., Boucau, Julie, Barczak, Amy K., Balazs, Alejandro B., Diamond, Michael S., Schmidt, Aaron G., Lingwood, Daniel, Bathe, Mark

“…Sequential immunization of mice with DNA-based VLPs (DNA-VLPs) elicits protective neutralizing antibodies to SARS-CoV-2 in a manner that depends on the valency of the antigen displayed and on T cell help. …”
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Real time analysis of social behavior from video and kinect recordings by Ramasamy, Pandi Ramesh

“…Finally,analysis will be performed using pattern recognition algorithms and machine learning classifiers to detect the emotion of the subject.In this project,machine learning classifiers such as K-nearest neighbors,Naive Bayes and C4.5 Decision tree learning has been used. The prime aim is to pin point the most seemly machine learning classifier for obtaining highest accuracy for classification.…”
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A systems biology approach to define SARS-CoV-2 correlates of protection in non-human primates by Brady, C

“…The relationship between spike antibody isotype, IgG subclass, glycosylation and functional responses, and the relationship between these properties and protection, was explored. …”

Existence and Analysis of a Rotating Stall Inception Continuum & Development of Concept Questions in Fluid Dynamics by Cherry, Maranda F.

“…The divergence of stall inception from two-dimensionality is suggested as a distinguishing feature of spike type stall inception compared to modal type stall inception. …”
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Characterization of cell types and connectivity of the deep cerebellar nuclei by Lim, Zoe Hui

“…Taken together, our results indicate that direct projections from the cerebellum to hippocampus and hypothalamus exist in mice and we have begun to characterize the cells from which these connections may arise.…”
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Developing optogenetics for use in vascular research by Rorsman, N

“…The light intensity range that enables optical control of arterial tone primarily through the recruitment of endogenous channels and without substantial alteration of intracellular pH, was identified. Within this range, mice expressing ChR2(H134R) in SMCs are a powerful experimental model for achieving accurate and tuneable optical voltage-clamp of SMCs and finely-graded control of arterial tone, offering new avenues to the discovery of vasorelaxing drugs.…”

Stress faced by executives in Singapore. by Par, Hwee Fong., Tan, Chin Ying., Thong, Hwei Ling.

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Challenges faced by women in the corporate world by Ang, Hui Jia, Sim, Jasmine Mei Yao, Yeo, Siew Hong

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Fabrication of heat sinks by Selective Laser Melting for convective heat transfer applications by Wong, Kin Keong, Ho, Jin Yao, Leong, Kai Choong, Wong, Teck Neng

“…Three heat sinks comprising pin fins of circular, rectangular-rounded and aerofoil geometries were fabricated by SLM from aluminium alloy AlSi10Mg powder. …”
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Comparative study of accounting standards between Singapore and the Peoples' Republic of China by Neo, Karn Nee, Siew, May San, Swi, Li Li

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Behavioural and biochemical abnormalities in a mouse model for Parkinson's disease. by Ten, Rachel Rui Xian.

“…There were no statistical differences in anxiety and depression-like behaviour between the non-transgenic and transgenic mice. These results were concomitant with good motor performance in both mice groups, though, contrary to published literature, motor deficits were not found in older (6 months old) mice. …”
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Convective boiling and condensation in enhanced tubes produced by selective laser melting by Tan, Choon Yong

“…The design of the four tubes are five long circumferential pin fins, eight short circumferential pin fins, twisted pin fins and a metallic foam structure. …”
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Interferon-γ- and glucocorticoid-mediated pathways synergize to enhance death of CD4(+) CD8(+) thymocytes during Salmonella enterica serovar Typhimurium infection by Deobagkar-Lele, M, Chacko, SK, Victor, ES, Kadthur, JC, Nandi, D

“…Upon infection, Ifnγ(-/-) mice display higher CFU and lower survival but more surviving thymocytes are recovered. …”

Serotonin transporter function and emotional behaviour by Lima, J

“…Moreover, 5-HTTKO mice exhibited superior aversive learning via augmented BLA function. …”

Fluorescence diffuse optical imaging for small animal study. by Lim, Shu Qiang.

“…The proposed idea is to capture images of fluorescence of the major internal organs and overlap it with general view of the mice so as to obtain exactly co-registered anatomical overlay images. …”
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Roles of leucine-rich alpha-2-glycoprotein 1 in normal and diabetic wound healing by Liu, Chenghao

“…Western blot analysis shows reduced formation of neutrophil extracellular traps in the wounds of diabetic Lrg1-/- mice. Neutrophils isolated from Lrg1-/- mice are less susceptible to inducer of ΝΕΤs formation. …”
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A two-dimensional co-rotational Timoshenko beam element with XFEM formulation by Xu, Jin, Lee, Chi King, Tan, Kang Hai

“…Pin connections and plastic hinges produce non-smooth displacement fields in beam structures. …”
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Hippocampal transcriptome profiling reveals common disease pathways in chronic hypoperfusion and aging by Baik, Sang-Ha, Selvaraji, Sharmelee, Fann, David Y., Poh, Luting, Jo, Dong-Gyu, Herr, Deron R., Zhang, Shenpeng R., Kim, Hyun Ah, Silva, Michael De, Lai, Mitchell K. P., Chen, Christopher Li- Hsian, Drummond, Grant R., Lim, Kah-Leong, Sobey, Christopher G., Arumugam, Thiruma V.

“…However, BCAS-induced changes in hippocampal gene expression differed between young and aged mice. Specifically, transcriptomic analysis indicated that in comparison to young sham mice, many pathways altered by BCAS in young mice resembled those already present in sham aged mice. …”
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