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2101
Multi-spectral polarimetry imaging for early gastric cancer diagnosis
Published 2016“…Gastric cancer, which develops from the lining of stomach, is the fifth most severe disease worldwide. …”
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Thesis -
2102
Cellular studies on the role of OGFOD1, a 2-oxoglutarate-dependent dioxygenase
Published 2017“…The transcriptional regulator, Thanatos associated protein 11 (THAP11) was identified as a novel high stoichiometry OGFOD1-interacting protein across a range of cell lines. Analysis of the THAP11 transcriptional programme in SW620 cells defined a repressive action of OGFOD1 overexpression on THAP11 DNA binding and target gene expression. …”
Thesis -
2103
The combined activation of KCa3.1 and inhibition of Kv11.1/hERG1 currents contribute to overcome Cisplatin resistance in colorectal cancer cells
Published 2020“…Methods: The functional expression of Ca2+-activated (KCa3.1, also known as KCNN4) and voltage-dependent (Kv11.1, also known as KCNH2 or hERG1) K+ channels was determined in two CRC cell lines (HCT-116 and HCT-8) by molecular and electrophysiological techniques. …”
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Journal Article -
2104
Towards depth-resolved multi-cubic-centimeter field of view endoscopic camera for intraoperative nerve identification.
Published 2024“…In the second component of this thesis, we provide extensive theoretical and experimental studies on how optical amplifiers can be used in OCT to address sensitivity challenges of high-speed surgical OCT platforms like CL-OCT. Together, these lines of research define a new approach to meeting the need for OCT-based solutions for intraoperative nerve identification. …”
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Thesis -
2105
P2P energy trading among isolated microgrids in the remote area
Published 2021“…As for the power supply in remote areas, the traditional transmission method by using the central grid has the drawbacks of large transmission loss and long transmission lines, which are easy to be broken. At the same time, there are areas where electricity is not available because of costly transmission losses, for the transmission networks are not yet widespread. …”
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Thesis-Master by Coursework -
2106
Induction of apoptosis and the signalling pathways involved by dillenia suffruticosa dichloromethane root extract in mcf-7 and mda-mb-231 breast cancer cells
Published 2015“…DCMDS induced apoptosis and oxidative stress in these two cell lines. Treatment with α- tocopherol reduced the cytotoxicity of DCM-DS at 50 µg/mL in the cells, suggesting that DCM-DS induced lipid peroxidation to destroy the cancer cells. …”
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Thesis -
2107
Biogenic amines and urocanic acid in keropok lekor, and their effects on cytotoxicity and proinflammatory mediator secretion of macrophage cell culture
Published 2017“…Future research on in vitro cytotoxicity effects of BAs in fishery products or other foods using different cell lines to resemble in vivo study is warranted.…”
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Thesis -
2108
Towards Synergistic Understanding of Language Processing in Biological and Artificial Systems
Published 2024“…Furthermore, the average degree of sentence straightening in the deep layers of the model correlates with corpus-based estimates of sentence surprisal, which are linked to human comprehension difficulty (e.g., as reflected in reading times). Collectively, these lines of work provide essential ingredients for building a more computationally precise model of language processing in the human brain, leveraging synergies with artificial neural network language models.…”
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Thesis -
2109
Development of an application to improve mental health (A)
Published 2023“…As the mental health concern grew, most countries developed new mental health information and phone support lines, offering tips to the public on coping measures. …”
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Final Year Project (FYP) -
2110
Grid optimization and demand side mangement for electric vehicles penetration in remote area
Published 2023“…Power grid model simulation: use government data to predict that Trincomalee's electricity demand will increase from the current 40MW to 640MW in five years and build a grid simulation model for Sri Lanka's national high-voltage transmission lines. Optimization will target transmission cables that provide higher voltage loads while considering cable properties includes resistance and reactance for optimal power loss and voltage drop respectively, thermal capacity, and power quality. …”
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Conference Paper -
2111
杜牧“‘秋’意象诗”研究 = Research on Du Mu’s autumn imagery poems
Published 2012“…Close reading will be used to uncover the emotions between the lines in Du Mu’s poems that may contain feelings other than grief. …”
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Final Year Project (FYP) -
2112
The effect of the amyloid-beta peptide on the fluidity of cell membranes : a study by fluorescence correlation spectroscopy
Published 2017“…To this end, we used imaging TIRF-fluorescence correlation spectroscopy (ITIR-FCS) to make measurements of fluidity of one bulk membrane probe, DiI, and two ordered/raft-type membrane probes, a transiently expressed GPI-linked GFP and cholera toxin subunit B, on the membranes of living cells that were exposed to Aβ. Three cell lines – SH-SY5Y human neuroblastoma, U87 human glioma and Neuro-2a mouse neuroblastoma – were selected for our study based on their origin in brain tissue and previous use in Aβ-related studies. …”
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Thesis -
2113
Climate change: crop performance and potential
Published 2011“…In addition, a biological control using other species of bamboo to reduce the domination of buluh semantan under high voltage transmission lines is also included. In the studies regarding growth of forest species meant for domestication purposes, the suitability of Syzygium campanulatum and Hopea odorata for beautification and landscaping plants has shown some potential. …”
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Inaugural Lecture -
2114
Dysregulation of the Pdx1/Ovol2/Zeb2 axis in dedifferentiated β-cells triggers the induction of genes associated with epithelial-mesenchymal transition in diabetes
Published 2022“…We carried out loss- and gain-of-function experiments in MIN6 and EndoC-bH1 cell lines. We analysed previously published mouse andhuman T2D data sets.Results:Bulk RNA-seq revealed thatb-cell dedifferentiation is associated with the induction of genes associated with epithelial-to-mesenchymal transition (EMT) in prediabetic (2-week-old) and diabetic (12-week-old) Tg7 mice. …”
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Journal Article -
2115
Engineering Mechanical Counter Pressure Spacesuits and Compression Garments: Active Pressurization and Design for Mobility
Published 2024“…The process of estimating the optimum fabric pattern will be iterative and the resulting pattern may comprise of a composite of different fabric types with varying parameters. Mapping skin Lines of Non-Extension (LoNE’s) informs contours for inextensible cables in such a way that they do not impede movements. …”
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Thesis -
2116
Content-based image retrieval with statistical machine learning.
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Thesis -
2117
Investigating the neural substrates of Chinese character processing
Published 2014“…The research framework consisted of two levels: direct and converging evidence, through three lines of investigations. Study 1 and Study 2 provided direct evidence of the neural mechanisms for Chinese character processing. …”
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Thesis -
2118
Instrumentation optimisation for unicompartmental knee replacement
Published 2024“…Cementless OUKRs (1/15) had fewer tibial radiolucent lines compared to cemented (6/14) at 10 years.</p> <p>Bearing fractures, because of excessive polyethylene wear, have been reported with the Phase III OUKR. …”
Thesis -
2119
ESBL and AmpC β-lactamase encoding genes in E. coli from pig and pig farm workers in Vietnam and their association with mobile genetic elements
Published 2021“…The isolates carrying the plasmids, even those with plasmids of similar types, showed wide genetic variation with high number of SNPs, suggesting horizontal spread of plasmids into different clonal lines. Their virulence profiles did not confirm to known pathotypes, suggesting that unrelated commensals are a main reservoir for ESBL and AmpC β-lactamases in both humans and pigs. …”
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Journal Article -
2120