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361
Epi-microRNA mediated metabolic reprogramming counteracts hypoxia to preserve affinity maturation
Published 2024“…Mechanistically, miR-155 regulates H3K36me2 levels in hypoxic conditions by directly repressing the histone lysine demethylase, Kdm2a, whose expression increases in response to hypoxia. …”
Journal article -
362
Parenting and infant cry
Published 2019“…This Special Issue collects five empirical studies from around the world that use diverse methodological approaches and focus at different levels to investigate how behavioral, hormonal, prenatal and postnatal factors, brain functioning, and environment regulate early interactions of parents with distressed infants and young children.…”
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Journal Article -
363
Implementation and control of a quadratic boost converter
Published 2021“…Various feedback controllers such as the Output Feedback Controller, Non-Adaptive Current Mode-Controller, Adaptive Current-Mode Controller, and the Sliding Mode-Controller are implemented to regulate the output voltage of the quadratic boost converter. …”
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Final Year Project (FYP) -
364
Opportunity for genome engineering to enhance phosphate homeostasis in crops
Published 2024“…Plants maintain cellular homeostasis of phosphate (Pi) through an integrated response pathway regulated by diferent families of transcription factors including MYB, WRKY, BHLH, and ZFP. …”
Article -
365
Technologies of the soul: ancient wisdom in the smart nation
Published 2023“…How should we respond to this crisis and from where might we find the wisdom to regulate ourselves from the onslaught of digital creep? …”
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Working Paper -
366
Molecular dynamics simulation studies of salting effects and ion-mediated molecular interactions
Published 2013“…More interest was paid to the mechanisms that cause protein denaturation in urea solution, the electrostatic and conformational effects that induce, stabilize and regulate DNA condensation in the presence of counterions. …”
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Thesis -
367
Functional amyloids in Pseudomonas aeruginosa may be involved in the sequestration of the quorum sensing molecules HHQ and PQS under high shear conditions.
Published 2013“…These signalling molecules regulate the formation of biofilm and production of virulence factors, hence playing a role in its pathogenicity. …”
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Final Year Project (FYP) -
368
Online learning with kernels
Published 2014“…On the other hand, to update the kernel weight, the traditional linear or nonlinear online learning algorithms are extended to RKHS to develop types of kernel online learning algorithms, such as the kernel recursive least square algorithms and the kernel (regularized) least mean square algorithms which incorporate suitable sparsification methods to select their kernel centers. …”
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Thesis -
369
A unified framework of active transfer learning for cross-system recommendation
Published 2017“…Based on the framework, we propose three solutions by specifying three state-of-the-art collaborative filtering methods, namely Maximum-Margin Matrix Factorization, Regularized Low-rank Matrix Factorization, and Probabilistic Matrix Factorization. …”
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Journal Article -
370
Is there a role for traction forces exerted at the polar regions in the cytokinesis of adherent cells?
Published 2009“…My results suggest that polar traction forces negatively regulate dividing cells’ separation into daughter cells by pulling them apart during cytokinesis.…”
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Final Year Project (FYP) -
371
On the improvement of executive functions via a group-based intervention program : a preliminary analysis
Published 2012“…Executive functions (EFs) are crucial cognitive processes that regulate children’s behaviors. In the present study, a group-based integrative EFs intervention program was developed for preschoolers. …”
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Final Year Project (FYP) -
372
A clinical perspective on muscle specific kinase antibody positive myasthenia gravis
Published 2024“…In healthy muscle, MuSK regulates a phosphorylation pathway, which is essential for the development and maintenance of acetylcholine receptor (AChR) clusters at the neuromuscular junction. …”
Journal article -
373
Oxytocin receptor gene and parental bonding modulate prefrontal responses to cries : a NIRS study
Published 2020“…The ability to interpret and regulate emotions relies on experiences of emotional socialization, obtained firstly through the interaction with the parents, and on genetic features that affect how individuals take on social situations. …”
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Journal Article -
374
MicroRNA trimming in the nervous system
Published 2013“…MicroRNAs are small, single-stranded RNAs about 22 nucleotides long which are involved in post-transcriptional regulation of mRNAs. MicroRNAs base-pair with regions on the 3’ UTR of target mRNAs which show partial complementarity to microRNA sequence and downregulate them by translational repression or mRNA cleavage. …”
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Student Research Poster -
375
Power quality enhancement of isolated power systems through series compensation
Published 2008“…A control strategy for the SC is developed to regulate power flow. This is achieved through phase adjustment of load terminal voltage. …”
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Thesis -
376
Explore anomaly detection and localization methods for medical imaging data
Published 2024“…Motivated by this, we introduce Contrastive Learning guided GAN (CLGAN), which leverages unlabeled mixed data and contrastive learning to guide the generation process. CLGAN regulates the generator by aligning generated images with the normal distribution while pushing them away from potential anomalies present in the unlabeled images. …”
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Final Year Project (FYP) -
377
Emergency depopulation of chicken farms during an avian influenza outbreak (Design and development of CO2 delivery system)
Published 2019“…Although the bird flu virus is endemic in the South East Asian region at the moment, the Agri-Food & Veterinary Authority of Singapore (AVA), a local statutory board that regulates food safety, has come up with several guidelines to not only prevent the introduction, but also to limit the spread of the virus. …”
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Final Year Project (FYP) -
378
Structural modeling of LAG-3 protein and immunoglobulin domains
Published 2014“…Lymphocyte-activation gene 3 (LAG3) is a protein that limits the activity of T-cells, which down regulates the immune system. The protein functions can be determined from its structure. …”
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Final Year Project (FYP) -
379
The role of Wee1 in the hypoxia-induced DNA damage response and its potential as a therapeutic target
Published 2012“…Wee1 is involved in G<sub>2</sub>-M progression; inhibitors of Wee1 force cells into premature mitosis causing damage as well as radiosensitising cells even under hypoxic conditions.</p> <p>Wee1 also regulates genomic stability via inhibition of the endonuclease Mus81-Eme1 in S phase cells. …”
Thesis -
380
The role of the spleen in mediating pathology in Plasmodium Yoelii (P.yoelii) infection
Published 2016“…The iRBC rigidity as modulated by the spleen was demonstrated to regulate disease outcome. Moreover, the early activation of pro-inflammatory responses in the spleen appears to help to control the parasite development, confirming that early spleen responses are a key factor in directing the clinical outcome of an infection. …”
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Thesis