Mechanistic action of weak acid drugs on biofilms by Kundukad, Binu, Schussman, Megan, Yang, Kaiyuan, Seviour, Thomas, Yang, Liang, Rice, Scott A., Kjelleberg, Staffan, Doyle, Patrick S.

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A room-temperature refuelable lithium, iodine and air battery by Tan, Kim Seng, Grimsdale, Andrew Clive, Yazami, Rachid

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Superior memory efficiency of quantum devices for the simulation of continuous-time stochastic processes by Elliott, Thomas Joseph, Gu, Mile

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Defining a critical period for inhibitory circuits within the somatosensory cortex by Lo, Shun Qiang, Sng, Judy C. G., Augustine, George J.

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A pilot study on peptidylarginine deiminases and protein deimination in animal cancers across vertebrate species by Inal, Jameel, Hristova, Mariya, Lange, Sigrun

“…While the roles for PADs in various human cancers are mounting (both in regards to cancer progression and epigenetic regulation), investigations into animal cancers are scarce. …”
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Goblet cell differentiation in colorectal cancer by Abdullayeva, G

“…We suggest that in the group 4 cell lines, MUC2 is most likely methylated as opposed to other group cell lines that might be regulated by demethylation of transcription factors, such as ATOH1 and HES1.…”

Characterizing the function of the Arl15 gene and its role in the development of metabolic traits by Bai, Y

“…</p> <p>In summary my data supports Arl15 as a candidate vesicle trafficking gene for craniofacial development, regulation of plasma adiponectin levels and sexually dimorphic altered body composition. …”

YAP-DKK1 axis restricts regeneration to the isthmus of the human gastric glands by Zagami, C

“…Interestingly, DKK1 expression was found to spatially correlate with and be regulated by YAP, a key coactivator acting via binding to the TEAD transcription factor of the mechano-sensing Hippo pathway.…”

Heterogeneity in definitions of surgical site infection after cranial surgery limits the validity of research findings in neurosurgery: a systematic review by Majidi, N, Sivakumar, A, Vogt, A, Ranganathan, S, Ashkan, K, Price, SJ, Lee, KS

“…The implementation of a new core indicator set could support uniform reporting of indicators along with regulation of reported SSI-CRAN outcomes, thereby facilitating more effective evidence synthesis.…”

Integrating alternative and complementary medicine in the management of epilepsy and its comorbidities in low- and middle-income settings by Kariuki, SM, Newton, CRJC

“…However, LMIC continue to lag in implementation of these policies and guidelines, especially in the areas of research and development and regulation of TCM practice. Working with stakeholders, countries are advised to assess their own national situations in relation to TCM, and then develop practical solutions to accommodate these approaches. …”

HSV-1 amplicon system for human artificial chromosome formation in human ES/iPS cells and pluripotency induction by Khoja, S

“…HAC offers many potential advantages including the provision for carrying large genes with corresponding regulatory elements to obtain long-term regulated gene expression. In addition, they can replicate and segregate independently without integration into the host cell genome. …”

Myth ascendant: issues of culture, media, and identity in the celebrity career of Glenn Gould by Campbell, A

“…This approach is refined through the application of Stuart Hall’s 'Circuit of Culture' model, which yields an understanding of Gould's celebrity in terms of the processes of its representation, production, regulation, and consumption. Against this theoretical backdrop, and consistent with the premise of my thesis, I ask some key questions: what was Gould's relationship to Canadian cultural nationalism and, specifically, a nationalist discourse of public broadcasting? …”

Elucidating the function of the suppressor of ppi1 locus 2 by Broad, W

“…To understand more about plastid development and the regulation of the TOC machinery, a screen for second-site suppressors of a mutant lacking the Toc33 receptor, called <em>plastid protein import 1 (ppi1)</em>, was previously conducted. …”

Functional characterisation of multiple sclerosis-­associated single nucleotide polymorphisms in the Eomesodermin region by Leach, O

“…Imputation analysis enabled detection of new variants, which aligned with regions of epigenetic significance and possible regions of DNA-interaction, implying an effect on regulation of gene expression. </p> <p>Subsequently, Eomes expression was characterised in peripheral blood cell populations, with the highest expression detected in natural killer cells and effector/memory T cell subsets, including MAIT cells, an innate-like lymphocyte population. …”

Due regard obligations in the law of the sea convention by Fasia, EE

“…Further, the analysis on interstitiality demonstrates that DROs serve as an organising principle of the LOSC, facilitating the consideration even of issues not explicitly regulated in the Convention. Lastly, the thesis makes a normative proposition that due regard should be viewed as a way to resolve broader law of the sea questions beyond the realm of the LOSC.…”

A loss-of-function mutation in KCNJ11 causing sulfonylurea-sensitive diabetes in early adult life by Vedovato, N, Salguero, MV, Greeley, SAW, Yu, CH, Philipson, LH, Ashcroft, FM

“…<p><strong>Results</strong></p> Functional analysis showed no changes in the ATP sensitivity or metabolic regulation of the mutant channel. However, the Kir6.2-S118L mutation impaired surface expression of the K_ATP channel by 40%, categorising this as a loss-of-function mutation. …”

Immune checkpoint blockade sensitivity and progression-free survival associates with baseline CD8+ T cell clone size and cytotoxicity by Watson, RA, Tong, O, Cooper, R, Taylor, CA, Sharma, PK, de Los Aires, AV, Mahé, EA, Ruffieux, H, Nassiri, I, Middleton, MR, Fairfax, BP

“…At the level of CD8⁺&nbsp;T cell clonotypes, we found a relationship between transcriptional changes and clone size, with large clones showing a greater number of differentially regulated genes enriched for pathways including T cell receptor (TCR) signaling. …”

The molecular pathogenesis of FUS mutations in amyotrophic lateral sclerosis using in vivo and in vitro models by Kent, L

“…Alterations in FUS distribution, stress granule dynamics, and regulation of transcription may all play a part in conferring a susceptibility to developing ALS.…”

Determination of elemental composition in Infant formula and growing up formula Among different brands available in Malaysia by Shafie, Wan Norfaezah Wan

“…Although almost all of the trace elements and heavy metal shows significant amount in both growing up and infant formula, however there were still below the permissible limit for all of the elements except for lead, according to Food Act 1983 and Food Regulation 1985.…”
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Simultaneous Tactile Estimation and Control of Extrinsic Contact by Kim, Sangwoon, Jha, Devesh K., Romeres, Diego, Patre, Parag, Rodriguez, Alberto

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