Towards understanding genome regulation via high-resolution analysis of chromatin accessibility by Dai, L

“…<p>Next generation sequencing has been used to in functional genomics to rep- resent specific aspects of chromatin structure, DNA-protein interactions and the epigenome, enriching the knowledge of the non-coding genome which plays significantly roles in gene regulation but is vaguely understood. Among the assays for functional genomics, Assay for Transposase-Accessible Chromatin using sequencing (ATAC-seq) is a powerful and popular tool as its simple read out of ‘chromatin accessibility’ provides both the positioning of functional regulatory elements and a general representation of the active genome. …”

Banks regulatory reforms in Singapore. by Foo, Cindy Ping Ping., Lee, Shirleen Sok Loon., Ng, Mui Chee.

Subjects: “…DRNTU::Business::Finance::Banking regulation…”
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The role of executive function in cognitive reappraisal: a meta-analytic review by Toh, Wei Xing, Keh, Jun Sheng, Gross, James J., Carstensen, Laura L.

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Design of a 40nm CMOS Internet-of-Things regulator with fast power on and off by Zhong, Si Yuan

“…Low Dropout (LDO) regulator is an important building block for Internet of Things (IoT) and System-on-Chip (SoC). …”
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Design of a fast response CMOS low dropout regulator for system-on-chip applications by Wang, Haoran

“…The Low-DropOut (LDO) regulator is regarded as one of the important building blocks in power management. …”
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Nuclei sorting-based genome-wide CRISPR screens to identify novel regulators of hepatic insulin signalling by Martin Perez, E

“…Hence, hepatic insulin action provides an important layer of regulation in the maintenance of whole-body metabolic homeostasis, and its dysregulation is closely associated with metabolic disease progression. …”

CD1d‐mediated lipid presentation by CD11c+ cells regulates intestinal homeostasis by Sáez de Guinoa, Julia, Jimeno, Rebeca, Gaya, Mauro, Kipling, David, Garzón, María J., Dunn‐Walters, Deborah, Ubeda, Carles, Barral, Patricia

“…Natural killer T (NKT) cells, which recognize CD1d‐restricted microbial lipids and self‐lipids, contribute to the regulation of mucosal immunity, yet the mechanisms underlying their functions remain poorly understood. …”
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A model for cis-regulation of transcriptional condensates and gene expression by proximal lncRNAs by Natarajan, Pradeep, Shrinivas, Krishna, Chakraborty, Arup K

“…Long noncoding RNAs (lncRNAs) perform several important functions in cells including cis-regulation of transcription. Barring a few specific cases, the mechanisms underlying transcriptional regulation by lncRNAs remain poorly understood. …”
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Regulation of lipid droplets in live preadipocytes using optical diffraction tomography and Raman spectroscopy by Hsieh, Chao-Mao, Liu, Patricia Yang, Chin, Lip Ket, Zhang, Jing Bo, Wang, Kuan, Sung, Kung-Bin, Ser, Wee, Bourouina, Tarik, Leprince-Wang, Yamin, Liu, Ai-Qun

“…However, it remains challenging to study the regulation of lipid droplets in live preadipocytes using conventional microscopic techniques. …”
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Study on the regulation of focal adesions and cortical actin by matrix nanotopography in 3D environment by Han, Jingjing, Lin, Keng-Hui, Chew, Lock Yue

“…Matrix nanotopography plays an important role in regulating cell behaviors by providing spatial as well as mechanical cues for cells to sense. …”
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Unraveling heterogeneity in transcriptome and its regulation through single-cell multi-omics technologies by Xing, Qiao Rui, Cipta, Nadia Omega, Hamashima, Kiyofumi, Liou, Yih-Cherng, Koh, Cheng-Gee, Loh, Yuin-Han

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Involuntary transnationalism and regulated precarity: lived experiences of skilled Chinese and Indian migrants in Singapore by Zhan, Shaohua, Zhou, Min

“…Based on analysis of survey data and in-depth interviews of skilled Chinese and Indian migrants in Singapore, we find that skilled foreign migrants face employment insecurity and other vulnerabilities largely due to visa regulations and that they have to turn to transnationalism as a coping strategy to mitigate precarity and temporality.…”
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Molecular study of Rasd1 transcriptional regulation and Rasd1-NonO interaction. by Ong, Angeline Shufen.

“…In this study, transcriptional regulation of Rasd1 and identification of novel interacting partner of Rasd1 are investigated to better understand how Rasd1 performs these physiological functions. …”
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Uncovering the function of CREB regulated transcription coactivator 2 (CRTC2) in rodent brain by Lim, Wei Lee

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Negative auto-regulation of myostatin expression is mediated by SMAD3 and microRNA-27 by Ge, XiaoJia, McFarlane, Craig, Vajjala, Anuradha, Arigela, Harikumar, Lokireddy, Sudarsanareddy, Bonala, Sabeera, Manickam, Ravikumar, Kambadur, Ravi, Sharma, Mridula

“…Here we show that miR-27a/b plays an important role in feed back auto-regulation of Mstn and thus regulation of post-natal myogenesis. …”
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Extensive promoter-centered chromatin interactions provide a topological basis for transcription regulation by Li, Guoliang, Ruan, Xiaoan, Auerbach, Raymond K., Sandhu, Kuljeet Singh, Zheng, Meizhen, Wang, Ping, Poh, Huay Mei, Goh, Yufen, Lim, Joanne, Zhang, Jingyao, Sim, Hui Shan, Peh, Su Qin, Mulawadi, Fabianus Hendriyan, Ong, Chin Thing, Orlov, Yuriy L., Hong, Shuzhen, Zhang, Zhizhuo, Landt, Steve, Raha, Debasish, Euskirchen, Ghia, Wei, Chia-Lin, Ge, Weihong, Wang, Huaien, Davis, Carrie, Fisher-Aylor, Katherine I., Mortazavi, Ali, Gerstein, Mark, Gingeras, Thomas, Wold, Barbara, Sun, Yi, Cheung, Edwin, Liu, Edison, Sung, Wing-Kin, Snyder, Michael, Ruan, Yijun, Fullwood, Melissa Jane

“…Higher-order chromosomal organization for transcription regulation is poorly understood in eukaryotes. Using genome-wide Chromatin Interaction Analysis with Paired-End-Tag sequencing (ChIA-PET), we mapped long-range chromatin interactions associated with RNA polymerase II in human cells and uncovered widespread promoter-centered intragenic, extragenic, and intergenic interactions. …”
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Treating the symptoms or the disease? Analysing the UK Online Safety Act's approach to digital regulation by Nash, V, Felton, L

“…In recent years, the pace of Internet regulation around the world has quickened, with states increasingly confident that they can and should hold major platform companies to account. …”

Natural variations in grain length 10 (GL10) regulate rice grain size by Zhan, P, Ma, S, Xiao, Z, Li, F, Wei, X, Lin, S, Wang, X, Ji, Z, Fu, Y, Pan, J, Zhou, M, Liu, Y, Chang, Z, Li, L, Bu, S, Liu, Z, Zhu, H, Liu, G, Zhang, G, Wang, S

“…Additionally, GL10 participates in the regulation of gibberellic acid (GA) signaling pathway genes in young panicle tissues. …”

Messenger and message: uncovering the roles, rhythm and regulation of extracellular vesicles in plant biotic interactions by Qiao, SA, Roth, R

Epigenetic drug screening identifies enzyme inhibitors A-196 and TMP-269 as novel regulators of sprouting angiogenesis by Beter, M, Pulkkinen, HH, Örd, T, Sormunen, A, Kilpeläinen, L, Dunford, JE, Kaikkonen, MU, Aavik, E, Laham-Karam, N, Oppermann, U, Laakkonen, JP, Ylä-Herttuala, S

“…We identified two epigenetic enzyme inhibitors as novel regulators of sprouting angiogenesis: A196, a selective SUV4-20H1/H2 inhibitor, demonstrated pro-angiogenic effects through increased H4K20me1 levels and upregulation of cell cycle associated genes, including MCM2 and CDK4. …”