Roles of leucine-rich alpha-2-glycoprotein 1 in normal and diabetic wound healing by Liu, Chenghao

“…Cell-based studies reveal that LRG1 differentially regulates TGFβ signaling pathway in keratinocytes, endothelial cells and fibroblasts. …”
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Position-space renormalization schemes for four-quark operators in HQET by Lin, Joshua, Detmold, William, Meinel, Stefan

“…X-space schemes are gauge-invariant, regulator-independent renormalization schemes that are defined by requiring position-space correlation functions of gauge-invariant operators to be equal to their noninteracting values at particular kinematic points. …”
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14-3-3 interaction with phosphodiesterase 8A sustains PKA signaling and downregulates the MAPK pathway by Mukherjee, Soumita, Roy, Somesh, Mukherjee, Shruti, Harikishore, Amaravadhi, Bhunia, Anirban, Mandal, Atin K.

“…The cAMP/PKA and mitogen-activated protein kinase (MAPK) signaling cascade control many cellular processes and are highly regulated for optimal cellular responses upon external stimuli. …”
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Rapid modulation of striatal cholinergic interneurons and dopamine release by satellite astrocytes by Stedehouder, J, Roberts, B, Raina, S, Bossi, S, Liu, AKA, Doig, N, McGerty, K, Magill, P, Parkkinen, L, Cragg, S

“…Astrocytes in striatum can regulate dopamine transmission by governing the extracellular tone of axonal neuromodulators, including GABA and adenosine. …”

Deubiquitinases in muscle physiology and disorders by Olie, CS, O'Brien, DP, Jones, HBL, Liang, Z, Damianou, A, Sur-Erdem, I, Pinto-Fernández, A, Raz, V, Kessler, BM

“…In vivo, muscle and neuronal cells are post-mitotic, and their function is predominantly regulated by proteostasis, a multilayer molecular process that maintains a delicate balance of protein homeostasis. …”

Recruitment of Cdc48 to chloroplasts by a UBX-domain protein in chloroplast-associated protein degradation by Li, N, Jarvis, RP

“…Chloroplast-associated protein degradation (CHLORAD) is a ubiquitin-dependent proteolytic system that regulates TOC. In CHLORAD, cytosolic Cdc48 provides motive force for the retrotranslocation of ubiquitinated TOC proteins to the cytosol but how Cdc48 is recruited is unknown. …”

Human genome editing after the “CRISPR babies”: the double-pacing problem and collaborative governance by Wang, Leifan, Shang, Lijun, Zhang, Weiwen

“…How to ensure the safe, effective, and ethical use of emerging biotechnologies, such as clustered regularly interspaced short palindromic repeats (CRISPR)-based genome editing, is a global challenge. …”
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Mitogenic activity of mesenchymal stem cells on hematopoietic stem cells via cellular analysis and gene expression by Mohadeseh, Hashem Boroojerdi

“…It has been recently revealed that the stromal precursor, mesenchymal stem cells (MSC) profoundly regulates the expansion and differentiation of HSC at bone marrow’s niche via producing hematopoietic growth factors and adhesion molecules. …”
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Role of posttranslational modifications of histone proteins in epigenetics by Raj, R

“…<p>Nature has evolved an additional level of genetic regulation by-passing direct changes in genetic code through the means of posttranslational modifications (PTMs) of nucleobases and histone proteins. …”

Towards the prevention of pressure ulcers by Kwek, Milton Sheng Yi

“…The up regulation of epidermal Cx43 is incidentally an observation also seen in publications regarding wound edges of human PUs. …”
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Low voltage low power output programmable OCL-LDO with embedded voltage reference by Nardi, Utomo, Teo, Terence Boon Chiat, Lim, Xian Yang, Venkadasamy, Navaneethan, Liu, Ziming, Tan, Chong Boon, Seah, Bryan Yun Da, Lam, Yvonne Ying Hung, Siek, Liter

“…The low voltage low power output-capacitorless (OCL) low dropout regulator (LDO) with embedded voltage reference (EVR) with adjustable and programmable output voltage is proposed in this paper. …”
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Epi-microRNA mediated metabolic reprogramming counteracts hypoxia to preserve affinity maturation by Nakagawa, R, Llorian, M, Varsani-Brown, S, Chakravarty, P, Camarillo, JM, Barry, D, George, R, Blackledge, NP, Duddy, G, Kelleher, NL, Klose, RJ, Turner, M, Calado, DP

“…Mechanistically, miR-155 regulates H3K36me2 levels in hypoxic conditions by directly repressing the histone lysine demethylase, Kdm2a, whose expression increases in response to hypoxia. …”

Metacognitive learning in a fully complex-valued radial basis function neural network by Suresh, Sundaram, Sundararajan, Narasimhan, Savitha, R.

“…Recent studies on human learning reveal that self-regulated learning in a metacognitive framework is the best strategy for efficient learning. …”
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MicroRNA trimming in the nervous system by Lee, Li Ming

“…MicroRNAs are small, single-stranded RNAs about 22 nucleotides long which are involved in post-transcriptional regulation of mRNAs. MicroRNAs base-pair with regions on the 3’ UTR of target mRNAs which show partial complementarity to microRNA sequence and downregulate them by translational repression or mRNA cleavage. …”
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Osteoprotegerin mediates adipogenesis in obesity by Lyu, Zipan, Chan, Yau-Tuen, Lu, Yuanjun, Lam, Tsz Fung, Wu, Xingyao, Wu, Junyu, Xu, Lin, Yang, Wei, Zhang, Cheng, Zhong, Linda Lidan, Wang, Ning

“…Osteoprotegerin (OPG), known for its role in bone metabolism regulation, emerges as a potential regulator in mediating adipogenesis during obesity onset. …”
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The role of bidirectional nucleocytoplasmic transport in apoptosis by Chan, Kheng Sze

“…Apoptosis or programmed cell death is a tightly controlled process regulated by many signaling pathways; however, the mechanisms and cellular events that decide whether a cell lives or dies remain poorly understood. …”
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Atherogenesis and plaque rupture, surface/interface-related phenomena by Siegel, G., Berkholz, J., Klüßendorf, D., Knosalla, C., Zakrzewicz, A., Ermilov, E., Malmsten, M., Lindman, Bjorn

“…In a previous work, we had found PML-NB, fibrous cap (collagens, proteoglycans) and HSBGF binding sites (e.g., TGFβ1) up-regulated and NFκB down-regulated. With this background knowledge we created a molecular feedback control circuit model where PML-NB functions as regulation centre, fibrous cap as controlled variable, HSBGF binding sites as receptor and NFκB as effector. …”
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Role of N-WASP in cell proliferation : implication for organ development and cancer by Verma, Apoorva

“…N-WASP regulates actin cytoskeleton and plays key roles in many cellular processes such as cell-proliferation, cell-adhesion, cell-migration and endocytosis which are essential for normal cell physiology. …”
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Accumulation, depuration and distribution of cadmium and zinc in the green-lipped mussel Perna viridis (Linnaeus) under laboratory conditions by Yap, C.K., Ismail, A., Tan, S.G., Omar, H.

“…Different rates of accumulation and depuration in soft tissues are found and this might be due to different mechanisms of metal binding and regulation. At the end of depuration, Cd levels in soft tissues of P. viridis were 10-30 times higher than before exposure, while Zn levels in soft tissues were almost similar to levels before exposure. …”
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Ultra low quiescent current slew rate enhanced OCL-LDO by Chua, Jocelyn Shin Hun

“…A high slew-rate amplifier is proposed in the Ultra-Low Quiescent Current Slew-Rate Enhanced OCL-LDO regulator design with improved transient response, using push-pull output to enhance driving capability that only requires ultra-low quiescent current (IQ ~1μA ). …”
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