The design of a CMOS only low-power low-voltage low-dropout voltage regulator (LDO) with an embedded voltage reference by Xie, Xinzhe

Subjects: “…Low-dropout (LDO) voltage regulator…”
Get full text

Proinflammatory cytokines suppress nonsense-mediated RNA decay to impair regulated transcript isoform processing in pancreatic β cells by Ghiasi, Seyed M., Marchetti, Piero, Piemonti, Lorenzo, Nielsen, Jens H., Porse, Bo T., Mandrup-Poulsen, Thomas, Rutter, Guy A.

“…Here, we investigate whether cytokines regulate NMD activity and identify transcript isoforms targeted in ß cells.…”
Get full text

Heme-Regulated eIF2α Kinase Modulates Hepatic FGF21 and is Activated by PPARβ/δ Deficiency by Zarei, Mohammad, Barroso, Emma, Leiva, Rosana, Barniol-Xicota, Marta, Pujol, Eugènia, Escolano, Carmen, Vázquez, Santiago, Palomer, Xavier, Pardo, Virginia, González-Rodríguez, Águeda, Valverde, Ángela M., Quesada-López, Tania, Villarroya, Francesc, Wahli, Walter, Vázquez-Carrera, Manuel

“…Increased Fgf21 was associated with enhanced protein levels in the heme-regulated eukaryotic translation initiation factor 2α (eIF2α) kinase (HRI). …”
Get full text
Get full text

Enhancing representation of data-scarce reservoir-regulated river basins using a hybrid DL-process based approach by Deng, L, Zhang, X, Slater, LJE

“…River discharge estimation in regulated river basins requires the inclusion of specific reservoir operation modules. …”

Super enhancer acquisition drives expression of oncogenic PPP1R15B that regulates protein homeostasis in multiple myeloma by Xiong, Sinan, Zhou, Jianbiao, Tan, Tze King, Chung, Tae-Hoon, Tan, Tuan Zea, Toh, Sabrina Hui-Min, Tang, Nicole Xin Ning, Jia, Yunlu, See, Yi Xiang, Fullwood, Melissa Jane, Sanda, Takaomi, Chng, Wee-Joo

Get full text

A KLF2-BMPER-Smad1/5 checkpoint regulates high fluid shear stress-mediated artery remodeling by Deng, H, Zhang, J, Wang, Y, Joshi, D, Pi, X, De Val, S, Schwartz, MA

“…Here we report that high FSS suppresses Smad1/5 by elevating KLF2, which induces the bone morphogenetic protein (BMP) pathway inhibitor, BMP-binding endothelial regulator (BMPER), thereby de-inhibiting Akt. In mice, surgically induced high FSS elevated BMPER expression, inactivated Smad1/5 and induced vessel outward remodeling. …”

TPPP acts downstream of RhoA-ROCK-LIMK2 to regulate astral microtubule organization and spindle orientation by Heng, Yi-Wen., Lim, Hong-Hwa., Mina, Theresia., Utomo, Prayudi., Zhong, Shaoping., Lim, Chwee-Teck., Koh, Cheng-Gee

“…Surprisingly, LIMK1 and cofilin are not involved downstream of RhoA and ROCK in the regulation of astral microtubule organization. Instead, we find that LIMK2 acts through TPPP in the regulation of astral microtubule organization, whereas both LIMK1 and LIMK2 affect centrosome focusing. …”
Get full text
Get full text

Regulation of mRNA abundance by polypyrimidine tract-binding protein-controlled alternate 5′ splice site choice by Hamid, Fursham M., Makeyev, Eugene V.

“…How alternate splice sites are selected by the splicing machinery and how AS is integrated into gene regulation networks remain important questions of eukaryotic biology. …”
Get full text
Get full text

Treatment with siRNAs is commonly associated with GPX4 up-regulation and target knockdown-independent sensitization to ferroptosis by von Mässenhausen, Anne, Schlecht, Marlena Nastassja, Beer, Kristina, Maremonti, Francesca, Tonnus, Wulf, Belavgeni, Alexia, Gavali, Shubhangi, Flade, Karolin, Riley, Joel S., Zamora Gonzalez, Nadia, Brucker, Anne, Becker, Jorunn Naila, Tmava, Mirela, Meyer, Claudia, Peitzsch, Mirko, Hugo, Christian, Gembardt, Florian, Angeli, Jose Pedro Friedmann, Bornstein, Stefan R., Tait, Stephen W. G., Linkermann, Andreas

“…In contrast, MAVS mediated a noncanonical signal resulting in a prominent increase in mitochondrial ROS levels, and increase in the BACH1/pNRF2 transcription factor ratio and GPX4 up-regulation, which was associated with a 50% decrease in intracellular glutathione levels. …”
Get full text

Media regulation in Singapore : empirical study of the instruments of media policy and its efficiency with regard to the attainment of political objectives by Carsten, Gäbel

“…Singapore's government justifies the regulation and control of the media by drawing on the “Developmental Concept”, a variation of authoritarian media theory that delineates the role of the media in developing countries. …”
Get full text

Importance of miRNA stability and alternative primary miRNA isoforms in gene regulation during Drosophila development by Zhou, Li, Lim, Mandy Yu Theng, Kaur, Prameet, Saj, Abil, Bortolamiol-Becet, Diane, Gopal, Vikneswaran, Tolwinski, Nicholas, Tucker-Kellogg, Greg, Okamura, Katsutomo

Subjects: Get full text
Get full text

Two models of dark triad traits and self-regulation dilemma predicting IP theft through self-deception by Yeo, Diana Mui Kheng

“…This study aimed to examine how dark triad personality traits and self-regulation dilemma is related to intellectual property (IP) theft. …”
Get full text
Get full text

Epigenetic drug screening identifies enzyme inhibitors A-196 and TMP-269 as novel regulators of sprouting angiogenesis by Beter, M, Pulkkinen, HH, Örd, T, Sormunen, A, Kilpeläinen, L, Dunford, JE, Kaikkonen, MU, Aavik, E, Laham-Karam, N, Oppermann, U, Laakkonen, JP, Ylä-Herttuala, S

“…We identified two epigenetic enzyme inhibitors as novel regulators of sprouting angiogenesis: A196, a selective SUV4-20H1/H2 inhibitor, demonstrated pro-angiogenic effects through increased H4K20me1 levels and upregulation of cell cycle associated genes, including MCM2 and CDK4. …”

The Response Regulator OmpR Negatively Controls the Expression of Genes Implicated in Tilimycin and Tilivalline Cytotoxin Production in Klebsiella oxytoca by Varela-Nájera, Ramón G., De la Cruz, Miguel A., Soria-Bustos, Jorge, González-Horta, Carmen, Delgado-Gardea, Ma Carmen E., Yáñez-Santos, Jorge A., Cedillo, María L., Hirakawa, Hidetada, Fox, James G., Sánchez-Ramírez, Blanca, Ares, Miguel A.

“…Our research highlights the pivotal role of OmpR, a key regulator within the EnvZ/OmpR two-component system, in controlling the virulence factors associated with K. oxytoca. …”
Get full text

Structural analyses of the AAA+ ATPase domain of the transcriptional regulator GtrR in the BDSF quorum-sensing system in Burkholderia cenocepacia by Yan, Xin-Fu, Yang, Chunxi, Wang, Mingfang, Yong, Yonlada, Deng, Yinyue, Gao, Yong-Gui

“…Global transcriptional regulator downstream RpfR (GtrR) is a key downstream regulator for quorum-sensing signaling molecule cis-2-dodecenoic acid (BDSF). …”
Get full text

Design and verification of a fast low-dropout regulator for a high performance receiver chain targeting GNSS applications by Debaditya, Mullick

“…Low-dropout (LDO) voltage regulators are arguably the most popular designs used in integrated circuit (IC) power management. …”
Get full text

Quad-faceted feature-based graph network for domain-agnostic text classification to enhance learning effectiveness by Supraja, S., Khong, Andy Wai Hoong

Subjects: Get full text

Comment to U.S Copyright Office on Data Provenance and Copyright by Mahari, Robert, Shayne, Longpre, Donewald, Lisette, Polozov, Alan, Pentland, Alex 'Sandy', Lipsitz, Ari

Subjects: Get full text

Photo-acoustic tomographic image reconstruction from reduced data using physically inspired regularization by Rejesh, Nadaparambil Aravindakshan, Kalva, Sandeep Kumar, Pramanik, Manojit, Arigovindan, Muthuvel

“…The regularization is constructed to suit the physical structure of typical PAT images. …”
Get full text

Guiding transition metal-doped hollow cerium tandem nanozymes with elaborately regulated multi-enzymatic activities for intensive chemodynamic therapy by Dong, Shuming, Dong, Yushan, Liu, Bin, Liu, Jing, Liu, Shikai, Zhao, Zhiyu, Li, Wenting, Tian, Boshi, Zhao, Ruoxi, He, Fei, Gai, Shili, Xie, Ying, Yang, Piaoping, Zhao, Yanli

“…This work presents a powerful paradigm to achieve intensive NCDT efficacy by simultaneously regulating multi-enzymatic activities of Ce-based nanozymes and perturbing the H2O2 homeostasis in tumor microenvironment.…”
Get full text