15.021J / 11.433J Real Estate Economics, Spring 2004 by Wheaton, William C., 1944-

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Understanding the role of transporters and ion channels in lysosomal homeostasis by Salphati, S

“…Cellular activity is regulated based on a range of cues to maintain homeostasis. …”

Opportunity for genome engineering to enhance phosphate homeostasis in crops by Abdullah, Siti Nor Akmar, Ariffin, Norazrin, Md Hatta, Muhammad Asyraf, Kemat, Nurashikin

“…Plants maintain cellular homeostasis of phosphate (Pi) through an integrated response pathway regulated by diferent families of transcription factors including MYB, WRKY, BHLH, and ZFP. …”

Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells by Head, Sarah A., Shi, Wei, Zhao, Liang, Gorshkov, Kirill, Pasunooti, Kalyan, Chen, Yue, Deng, Zhiyou, Li, Ruo-jing, Shim, Joong Sup, Tan, Wenzhi, Hartung, Thomas, Zhang, Jin, Zhao, Yingming, Colombini, Marco, Liu, Jun O.

“…Previous mechanistic studies have shown that itraconazole inhibits the mechanistic target of rapamycin (mTOR) signaling pathway, which is known to be a critical regulator of endothelial cell function and angiogenesis. …”
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Identification of novel interactions between MicroRNAs and pattern-recognition receptor signalling in dentritic cells by Pichulik, T

“…Recent evidence has suggested that PRR signalling regulates the expression of microRNAs (miRNAs), important post-transcriptional regulators of gene expression, which have been shown to fine-tune innate immune responses.…”

The zinc-finger transcription factor Blimp1/Prdm1 is required for uterine remodelling and repair in the mouse by Xypolita, M, Goolam, M, Bikoff, EK, Robertson, EJ, Mould, AW

“…The zinc finger transcription factor Blimp1/PRDM1 regulates gene expression in diverse cell types. Its activity controls the maternal decidual response at early post-implantation stages of development. …”

CRISPR-Cas9-mediated gene editing of MYB28 genes impair glucoraphanin accumulation of Brassica oleracea in the field by Neequaye, M, Stavnstrup, S, Harwood, W, Lawrenson, T, Hundleby, P, Irwin, J, Troncoso-Rey, P, Saha, S, Traka, MH, Mithen, R, Ostergaard, L

“…In this study, we sought to study the role of MYB28 in the regulation of aliphatic glucosinolate (A-GSL) biosynthesis and associated sulfur metabolism in field-grown Brassica oleracea with the use of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Cas9 gene-editing technology. …”

All MOS low-power low-voltage LDO with an embedded voltage reference by Chor, Chee Yong

“…A low dropout (LDO) voltage regulator with embedded voltage reference (EVR) where all MOSFETs are biased in weak inversion (sub-threshold region) except the pass transistor, generating a mean regulated voltage of 620.3 mV at full load (10 mA) under 1.2-V supply voltage, has been designed and simulated. …”
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Critical role for cold shock protein YB-1 in cytokinesis by Mehta, Sunali, Algie, Michael, Al-Jabry, Tariq, McKinney, Cushla, Kannan, Srinivasaraghavan, Verma, Chandra Shekhar, Ma, Weini, Zhang, Jessie, Bartolec, Tara K., Masamsetti, V. Pragathi, Parker, Kim, Henderson, Luke, Gould, Maree L., Bhatia, Puja, Harfoot, Rhodri, Chircop, Megan, Kleffmann, Torsten, Cohen, Scott B., Woolley, Adele G., Cesare, Anthony J., Braithwaite, Antony

“…Our results establish phosphorylated YB-1 as a critical regulator of cytokinesis, defining precisely how YB-1 regulates cell division.…”
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Roles of leucine-rich alpha-2-glycoprotein 1 in normal and diabetic wound healing by Liu, Chenghao

“…Cell-based studies reveal that LRG1 differentially regulates TGFβ signaling pathway in keratinocytes, endothelial cells and fibroblasts. …”
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Position-space renormalization schemes for four-quark operators in HQET by Lin, Joshua, Detmold, William, Meinel, Stefan

“…X-space schemes are gauge-invariant, regulator-independent renormalization schemes that are defined by requiring position-space correlation functions of gauge-invariant operators to be equal to their noninteracting values at particular kinematic points. …”
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Deubiquitinases in muscle physiology and disorders by Olie, CS, O'Brien, DP, Jones, HBL, Liang, Z, Damianou, A, Sur-Erdem, I, Pinto-Fernández, A, Raz, V, Kessler, BM

“…In vivo, muscle and neuronal cells are post-mitotic, and their function is predominantly regulated by proteostasis, a multilayer molecular process that maintains a delicate balance of protein homeostasis. …”

An RRM–ZnF RNA recognition module targets RBM10 to exonic sequences to promote exon exclusion by Collins, Katherine M., Kainov, Yaroslav A., Christodolou, Evangelos, Ray, Debashish, Morris, Quaid, Hughes, Timothy, Taylor, Ian A., Makeyev, Eugene V., Ramos, Andres

“…RBM10 recognizes a diverse set of RNA motifs in introns and exons and regulates alternative splicing. However, the molecular mechanisms underlying this seemingly relaxed sequence specificity are not understood and functional studies have focused on 3΄ intronic sites only. …”
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Mitogenic activity of mesenchymal stem cells on hematopoietic stem cells via cellular analysis and gene expression by Mohadeseh, Hashem Boroojerdi

“…Important genes that involve in controlling the number of HSC such as self-renewal related signaling pathway regulator genes cell cycle and apoptosis regulator genes were categorized by online DAVID software. …”
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BswR controls bacterial motility and biofilm formation in Pseudomonas aeruginosa through modulation of the small RNA RsmZ by Wang, Chao, Ye, Fuzhou, Kumar, Veerendra, Gao, Yong-Gui, Zhang, Lian-Hui

“…Pseudomonas aeruginosa relies on cell motility and ability to form biofilms to establish infections; however, the mechanism of regulation remains obscure. Here we report that BswR, a xenobiotic response element-type transcriptional regulator, plays a critical role in regulation of bacterial motility and biofilm formation in P. aeruginosa. …”
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Development of quorum-sensing circuits for metabolic flux control in Escherichia coli by Dinh, Christina V.

“…This thesis aims to develop autonomous and pathway-independent regulation tools that can be applied to controlling metabolic fluxes in these contexts to improve production. …”
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Metacognitive learning in a fully complex-valued radial basis function neural network by Suresh, Sundaram, Sundararajan, Narasimhan, Savitha, R.

“…Recent studies on human learning reveal that self-regulated learning in a metacognitive framework is the best strategy for efficient learning. …”
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Role of N-WASP in cell proliferation : implication for organ development and cancer by Verma, Apoorva

“…N-WASP regulates actin cytoskeleton and plays key roles in many cellular processes such as cell-proliferation, cell-adhesion, cell-migration and endocytosis which are essential for normal cell physiology. …”
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NMR structure, dynamics and interactions of the integrin β2 cytoplasmic tail with filamin domain IgFLNa21 by Chatterjee, Deepak, Tan, Suet-Mien, Bhattacharjya, Surajit, Lu, Lewis Zhiping

“…The actin-binding cytoskeletal protein filamin A is a negative regulator of integrin activation. The IgFLNa21 domain of filamin A binds to the C-terminus of β2 CT that contains a TTT-motif. …”
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Phase-field modeling of interfacial debonding in multi-phase materials via an adaptive isogeometric-meshfree approach by Li, Weidong, Nguyen-Thanh, Nhon, Zhou, Kun

“…In this modeling, the crack and interface phase fields are introduced for the regularized representations of crack surfaces and interfaces, respectively, and a convenient approach is proposed for implementing the regularized energy related to both crack surfaces and interfaces without requiring the line integration along them. …”
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