Ultra low quiescent current slew rate enhanced OCL-LDO by Chua, Jocelyn Shin Hun

“…A high slew-rate amplifier is proposed in the Ultra-Low Quiescent Current Slew-Rate Enhanced OCL-LDO regulator design with improved transient response, using push-pull output to enhance driving capability that only requires ultra-low quiescent current (IQ ~1μA ). …”
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REST targets JAK–STAT and HIF-1 signaling pathways in human Down syndrome brain and neural cells by Huang, Tan, Fakurazi, Sharida, Cheah, Pike-See, Ling, King-Hwa

“…The transcription repressor, Repressor Element-1 Silencing Transcription factor (REST), which acts as an epigenetic regulator, is a crucial regulator of neuronal and glial gene expression. …”
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The habenula clock influences response to a stressor by Basnakova, Adriana, Cheng, Ruey-Kuang, Chia, Joanne Shu Ming, D'Agostino, Giuseppe, Suryadi, Tan, Germaine Jia Hui, Langley, Sarah Raye, Jesuthasan, Suresh

“…We focus on the habenula, a mediator of threat response that functions by regulating neuromodulator release, and use zebrafish as the experimental system. …”
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Co-optation of B Cell Developmental States in Malignancy and Autoimmunity by Ramseier, Michelle L.

“…Transcriptional states provide a useful lens for understanding the diversity of cell identity and function. Cell state is regulated through both cell-intrinsic and -extrinsic mechanisms, and can diversify through tightly regulated transitions. …”
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Advanced diagnosis of electrical systems by Cao, Huimin

“…Two kind of faults are investigated in this project: sensor measurement error and power cell fault. “l1 regularized least-squares optimization” method is employed for sensor fault identification. …”
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Global response of Vibrio cholerae to predation by heterotrophic protists by Hu, Jie

“…Among them, 93 transcripts were up-regulated and 198 were down-regulated. Transcripts differentially expressed included biosynthetic and metabolic genes, flagellar and chemotaxis genes, genes encoding cell wall and outer membrane proteins, and transcriptional and translational regulators. …”
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The cyclic AMP-Vfr signaling pathway in Pseudomonas aeruginosa is inhibited by cyclic di-GMP by Almblad, Henrik, Harrison, Joe J., Rybtke, Morten, Groizeleau, Julie, Givskov, Michael, Parsek, Matthew R., Tolker-Nielsen, Tim

“…Overproduction of c-di-GMP causes a decrease in the transcription of virulence factor genes that are regulated by the global virulence regulator Vfr. The low level of Vfr-dependent transcription is caused by a low level of its coactivator, cyclic AMP (cAMP), which is decreased in response to a high level of c-di-GMP. …”
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Backbone boogie : dance the osteoporosis away! by Gey, Elainn Yee Rong, Lim, Cheryl Yi Xuan, Tan, Cammie Yi Jia

“…The campaign focuses on raising awareness of this health issue and encouraging the adoption of dance as a regular form of exercise among working women in Singapore aged 30 to 50. …”
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Overmodulation of constant-switching-frequency-based DTC for reluctance synchronous motors incorporating field-weakening operation by Zhang, Xinan, Foo, Gilbert Hock Beng

“…To overcome the problems of high torque ripples and variable switching frequency experienced by conventional direct torque control (DTC), constant-switching-frequency-based torque regulator is employed. By combining the proposed overmodulation scheme with this torque regulator, the dynamic torque response and constant power speed range of RSM drives are improved. …”
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A portable low-power blood pressure monitor for smartphones by Poh, Jacqqie Chao Yan

“…There is a need for automated blood pressure monitors that are portable and convenient to use to entice users to take blood pressure readings regularly whenever and wherever. In this project, a personal automated blood pressure monitor (PABM) prototype is realized. …”
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Natural variation of OsWRKY23 drives difference in nitrate use efficiency between indica and japonica rice by Zhang, S, Ji, Z, Jiao, W, Shen, C, Qin, Y, Huang, Y, Huang, M, Kang, S, Liu, X, Li, S, Mo, Z, Yu, Y, Jiang, B, Tian, Y, Wang, L, Song, Q, Wang, S, Li, S

“…Introducing efficient NO3‒ utilization alleles from indica into japonica could improve NUE, and at the same time uncover unknown regulators of NO3‒ metabolism. Here, we identify OsWRKY23 as a key regulator of NO3‒ uptake and NUE differences between indica and japonica rice. …”

Improving rice nitrogen-use efficiency by modulating a novel monouniquitination machinery for optimal root plasticity response to nitrogen by Huang, Y, Ji, Z, Tao, Y, Wei, S, Jiao, W, Fang, Y, Jian, P, Shen, C, Qin, Y, Zhang, S, Li, S, Liu, X, Kang, S, Tian, Y, Song, Q, Harberd, NP, Wang, S, Li, S

“…RNR10 encodes an F-box protein that interacts with a negative regulator of auxin biosynthesis, DNR1 (DULL NITROGEN RESPONSE1). …”

14-3-3 interaction with phosphodiesterase 8A sustains PKA signaling and downregulates the MAPK pathway by Mukherjee, Soumita, Roy, Somesh, Mukherjee, Shruti, Harikishore, Amaravadhi, Bhunia, Anirban, Mandal, Atin K.

“…The cAMP/PKA and mitogen-activated protein kinase (MAPK) signaling cascade control many cellular processes and are highly regulated for optimal cellular responses upon external stimuli. …”
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The enhancer RNA ARIEL activates the oncogenic transcriptional program in T-cell acute lymphoblastic leukemia by Tan, Shi Hao, Leong, Wei Zhong, Ngoc, Phuong Cao Thi, Tan, Tze King, Bertulfo, Fatima Carla, Lim, Mei Chee, An, Omer, Li, Zhenhua, Yeoh, Allen Eng Juh, Tenen, Daniel G., Sanda, Takaomi, Fullwood, Melissa Jane

“…The oncogenic transcription factor TAL1 regulates the transcriptional program in T-ALL. ARID5B is one of the critical downstream targets of TAL1, which further activates the oncogenic regulatory circuit in T-ALL cells. …”
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Structural and molecular characterization of ligands activating the orphan nuclear receptor Nurr1 (NR4A2) by Ng, Xin Yi

“…Extending from previous studies done by our lab, small molecule ligands were designed to target a plausible co-regulator binding pocket which was unveiled following L1 binding on the ligand binding domain (LBD) of Nurr1. …”
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Computational analysis for infectious diseases surveillance and host-pathogen interactions (in the context of Influenza A viruses) by Beyene, Biruhalem Taye

“…The functional annotations (pathways) and the highly expressed cell-specific signatures indicated that IAVs up-regulated host factors could induce virus infectivity (e.g. …”
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Selling personal insurance in Singapore by Kho Cheow Chuan, Phua Ban Guan, Tay Hai Keong Daryl

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Genome-wide mapping of Hif-1α binding sites in zebrafish by Greenald, David, Jeyakani, Justin, Pelster, Bernd, Sealy, Ian, Mathavan, Sinnakaruppan, van Eeden, Fredericus J.

“…Background: Hypoxia Inducible Factor (HIF) regulates a cascade of transcriptional events in response to decreased oxygenation, acting from the cellular to the physiological level. …”
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Blue bits : archives of the average hour by Tan, Jeremy Jie Ming

“…I have archived the end of a year alongside four individuals with whom I interact regularly. The final outcome is a visual archive housed within an exhibition space, therein also containing a collection of design objects that comprise illustrations, print material, and found ephemera that serve to accentuate the concept of the project, encapsulating the objective archival of an eventful uneventful November to December 2015.…”
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Ethics and Law for School Psychologists : A Vignette-Based Workbook / by Whalen, Angela, author 655199, Diamond, Elena, author 655200, John Wiley & Sons (Online service) 647106

“…The book includes a throughgoing focus on social justice and equity that prepares students and professionals to confidently respond to the complex challenges regularly presented in school psychology. The authors bridge the gap between ethics and law coursework and real-world ethical and legal dilemmas by offering opportunities for practice applying robust decision-making models to vignettes and cases distilled from the authors' experiences in practice. …”
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