Impact of BREXIT on key stakeholders of the maritime industry in UK by Ching, Claudia Loke Wei

“…By and large, UK will generally experience detrimental effects in the near future, but the long term effects of BREXIT still awaits to be seen as UK seeks to establish new trade relations and construct necessary infrastructure in supporting the UK economy post-BREXIT. UK shipping lines and port operators are therefore recommended to look to alternative sources of labour to replace the productivity gap of the EU nationals in the worst case scenario of a hard BREXIT should restrictions in the free movement of labour occur after BREXIT. …”
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In vitro and in silico investigation of TRPC3 mechanism and dynamics by Collingridge, J

“…This work provides computational evidence for the ability of TRPC3 to form a widely conserved, mechanistically important π-helix structural component in the pore-lining S6 helix. This has not previously been reported for TRPC3, and simulations presented here suggest a role for the π-helix in promoting a transition towards an open state of the channel. …”

Psoriatic Arthritis Priority Setting Partnership: patient and clinician informed considerations for future UK health service delivery by James, L, Hailey, L, Bundy, C, Burstow, H, Chandler, D, Cowper, R, Helliwell, P, Joannes, L, Kelly, A, Kennedy, B, Kinsella, S, McAteer, H, Mukherjee, S, Packham, J, Wise, E, Young, H, Dures, E, Coates, LC

“…Further analysis within the rheumatology service theme revealed additional sub-themes that emphasised integrating multidisciplinary services, improving access to advice lines and ensuring fair access to treatments.</p> <br> <p><strong>Conclusion:</strong> The five key themes provide valuable insights into the important areas of interest within health service delivery in the UK. …”

Nebular dominated galaxies: insights into the stellar initial mass function at high redshift by Cameron, AJ, Katz, H, Witten, C, Saxena, A, Laporte, N, Bunker, A

“…In contrast, modelling the spectrum as primarily nebular provides a good fit to both the continuum and emission lines, motivating scenarios in which (a) we are observing only nebular emission or (b) the ionizing source is powering extreme nebular emission that outshines the stellar emission. …”

Investigating the contribution of the unfolded protein response to prostate cancer bone metastasis by Kaya, Z

“…Using paired androgen refractory cancer of the prostate (ARCaP) cell lines ARCaPE and ARCaPM which differ in their epithelial (E) and mesenchymal (M) characteristics, I found that components of IRE1 and ATF6 ER stress pathways are higher in ARCaPE cells than in ARCaPM and decreased upon osteogenic differentiation of ARCaPM cells. …”

Engineering control of rhizobacteria for plant growth promotion by Green, PWL

“…The rhizopine system was used to demonstrate tight transcriptional control of the NifA master transcriptional regulator of <em>nif</em> genes for nitrogen fixation <em>in vitro</em>, thereby developing a rhizopine responsive diazotrophic strain which can be assayed for plant growth promotion on rhizopine producing barley lines. To test the feasibility of controlled synthetic symbiosis in a nodule environment, rhizopine control of nitrogen fixation was assayed in the model symbiotic rhizobium <em>S. meliloti</em>. …”

Physical properties of keropok (fried crisps) in relation to the amylopectin content of the starch flours by Mohamed, Suhaila, Abdullah, Norakiah, Muthu, Mangayar Karasi

“…Linear expansion, oil absorption and elasticity were positively correlated to the total amylopectin content in the whole flour (r2 = 0.99, 0.97 and 0.97 respectively). The best fitted lines for prediction of linear expansion, oil absorption and elasticity of the fried crisps were 21y ≦ 0.35x ‐ 162, y=0.15x‐ 74 and y=0.0008x‐0.41 respectively, where x is the amylopectin content of the whole flour. …”

Modulating electronic and geometric structure of transition metal compounds for efficient water splitting by Tang, Shasha

“…Furthermore, the CoMoO6 and CoMo2S4 cross-linked porous nanoflakes are investigated as bifunctional electrocatalysts for overall water electrolysis. …”
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Association between COVID-19 outcomes and mask mandates, adherence, and attitudes by Adjodah, Dhaval, Dinakar, Karthik, Chinazzi, Matteo, Fraiberger, Samuel P., Pentland, Alex, Bates, Samantha, Staller, Kyle, Vespignani, Alessandro, Bhatt, Deepak L.

“…We also find that mask mandates are linked to a 23.4 percentage point increase in mask adherence in four diverse states. …”
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Transcriptomic changes in oligodendrocytes and precursor cells associate with clinical outcomes of Parkinson’s disease by Dehestani, Mohammad, Kozareva, Velina, Blauwendraat, Cornelis, Fraenkel, Ernest, Gasser, Thomas, Bansal, Vikas

“…We found a significant association of oligodendrocytes (ODCs) and oligodendrocyte precursor cells (OPCs) with PD-linked risk loci and report several dysregulated genes and pathways, including regulation of tau-protein kinase activity, regulation of inclusion body assembly and protein processing involved in protein targeting to mitochondria. …”
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Inter-laboratory comparison of eleven quantitative or digital PCR assays for detection of proviral bovine leukemia virus in blood samples by Pluta, Aneta, Jaworski, Juan P., Droscha, Casey, VanderWeele, Sophie, Taxis, Tasia M., Valas, Stephen, Brnić, Dragan, Jungić, Andreja, Ruano, María J., Sánchez, Azucena, Murakami, Kenji, Nakamura, Kurumi, Puentes, Rodrigo, De Brun, MLaureana

“…Agreement amongst different assays was linked to BLV copy numbers present in samples and the characteristics of each assay (i.e., BLV target sequence). …”
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ProtAgents: Protein discovery via large language model multi-agent collaborations combining physics and machine learning by Ghafarollahi, Alireza, Buehler, Markus J.

“…Current methodologies for protein design often rely on AI-based models, such as surrogate models that address end-to-end problems by linking protein structure to material properties or vice versa. …”
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Hidden Influence in Dynamic Networks by Erhardt, Keeley Donovan

“…These networks consist of nodes (entities) and edges (connections) that dynamically evolve, reflecting changes in relationships, the emergence of new entities, and the dissolution of old links. Unlike static networks, which offer a snapshot of connections at a specific time, dynamic networks allow for modeling processes and system-level changes over time. …”
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Skeletal myotubes expressing ALS mutant SOD1 induce pathogenic changes, impair mitochondrial axonal transport, and trigger motoneuron death by Martínez, Pablo, Silva, Mónica, Abarzúa, Sebastián, Tevy, María F., Jaimovich, Enrique, Constantine-Paton, Martha, Bustos, Fernando J., van Zundert, Brigitte

“…A large body of evidence shows that astrocytes expressing ALS-linked mutant proteins cause non-cell autonomous toxicity of MNs. …”
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Effect of a high strength chemical industry wastewater on microbial community dynamics and mesophilic methane generation by Venkatakrishnan, Harish, Tan, Youming, Majid, Maszenan bin Abdul, Pathak, Santosh, Sendjaja, Antonius Yudi, Li, Dongzhe, Liu, Jerry Jian Lin, Zhou, Yan, Ng, Wun Jern

“…This study suggested that the degradation of organic components within the high strength industrial wastewater is closely linked with the activity of certain niche microbial communities within eubacteria and methanogens.…”
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3D carbon/cobalt-nickel mixed-oxide hybrid nanostructured arrays for asymmetric supercapacitors by Zhu, Jianhui, Jiang, Jian, Sun, Zhipeng, Luo, Jingshan, Fan, Zhanxi, Huang, Xintang, Zhang, Hua, Yu, Ting

“…Two such supercapacitors linked in series can simultaneously power four distinct light-emitting diode indicators; they can also drive the motor of remote-controlled model planes. …”
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Simultaneous binding of hybrid molecules constructed with dual DNA-binding components to a G-quadruplex and its proximal duplex by Asamitsu, Sefan, Obata, Shunsuke, Phan, Anh Tuân, Hashiya, Kaori, Bando, Toshikazu, Sugiyama, Hiroshi

“…By means of circular dichroism (CD), fluorescence resonance energy transfer (FRET), surface plasmon resonance (SPR), and NMR techniques, we showed the dual and simultaneous recognition of the respective segment via hybrid molecules, and the synergistic and mutual effect of each binding component that was appropriately linked on higher binding affinity and modest sequence specificity. …”
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Insight into the lateral ride discomfort thresholds of young-adult bus passengers at multiple postures : case of Singapore by Nguyen, Teron, NguyenDinh, Nen, Lechner, Bernhard, Wong, Yiik Diew

“…Lateral ride discomfort thresholds were thus established for bus negotiating roundabouts, intersections and along links. The three levels of ride discomfort are Uncomfortable, Very Uncomfortable and Extremely Uncomfortable with average lateral accelerations of ay = 1.5, 1.75 and 2.0 m/s2, respectively. …”
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NaTi₂(PO₄)₃ hollow nanoparticles encapsulated in carbon nanofibers as novel anodes for flexible aqueous rechargeable sodium-ion batteries by He, Bing, Yin, Kuibo, Gong, Wenbin, Xiong, Yuwei, Zhang, Qichong, Yang, Jiao, Wang, Zhixun, Wang, Zhe, Chen, Mengxiao, Man, Ping, Coquet, Philippe, Yao, Yagang, Sun, Litao, Wei, Lei

“…Herein, hollow-structure NTP evenly encapsulated in cross-linked porous N-doped carbon nanofiber (HNTP@PNC) is prepared through electrospinning technology and subsequent carbonization treatment, directly acting as binder-free anode for flexible ARSIBs. …”
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Identification of RNA-Tis11b complexes in activated B cells. by Tang, Ngang Heok.

“…Our data suggest that Tis11b may play a role during B cell activation processes and SB1/56.6 antibody could be used in cross-linking immunoprecipitation (CLIP) experiment to identify full spectrum of RNA targets of Tis11b. …”
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