Impact of BREXIT on key stakeholders of the maritime industry in UK by Ching, Claudia Loke Wei

“…By and large, UK will generally experience detrimental effects in the near future, but the long term effects of BREXIT still awaits to be seen as UK seeks to establish new trade relations and construct necessary infrastructure in supporting the UK economy post-BREXIT. UK shipping lines and port operators are therefore recommended to look to alternative sources of labour to replace the productivity gap of the EU nationals in the worst case scenario of a hard BREXIT should restrictions in the free movement of labour occur after BREXIT. …”
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In vitro and in silico investigation of TRPC3 mechanism and dynamics by Collingridge, J

“…This work provides computational evidence for the ability of TRPC3 to form a widely conserved, mechanistically important π-helix structural component in the pore-lining S6 helix. This has not previously been reported for TRPC3, and simulations presented here suggest a role for the π-helix in promoting a transition towards an open state of the channel. …”

Psoriatic Arthritis Priority Setting Partnership: patient and clinician informed considerations for future UK health service delivery by James, L, Hailey, L, Bundy, C, Burstow, H, Chandler, D, Cowper, R, Helliwell, P, Joannes, L, Kelly, A, Kennedy, B, Kinsella, S, McAteer, H, Mukherjee, S, Packham, J, Wise, E, Young, H, Dures, E, Coates, LC

“…Further analysis within the rheumatology service theme revealed additional sub-themes that emphasised integrating multidisciplinary services, improving access to advice lines and ensuring fair access to treatments.</p> <br> <p><strong>Conclusion:</strong> The five key themes provide valuable insights into the important areas of interest within health service delivery in the UK. …”

Nebular dominated galaxies: insights into the stellar initial mass function at high redshift by Cameron, AJ, Katz, H, Witten, C, Saxena, A, Laporte, N, Bunker, A

“…In contrast, modelling the spectrum as primarily nebular provides a good fit to both the continuum and emission lines, motivating scenarios in which (a) we are observing only nebular emission or (b) the ionizing source is powering extreme nebular emission that outshines the stellar emission. …”

Investigating the contribution of the unfolded protein response to prostate cancer bone metastasis by Kaya, Z

“…Using paired androgen refractory cancer of the prostate (ARCaP) cell lines ARCaPE and ARCaPM which differ in their epithelial (E) and mesenchymal (M) characteristics, I found that components of IRE1 and ATF6 ER stress pathways are higher in ARCaPE cells than in ARCaPM and decreased upon osteogenic differentiation of ARCaPM cells. …”

Engineering control of rhizobacteria for plant growth promotion by Green, PWL

“…The rhizopine system was used to demonstrate tight transcriptional control of the NifA master transcriptional regulator of <em>nif</em> genes for nitrogen fixation <em>in vitro</em>, thereby developing a rhizopine responsive diazotrophic strain which can be assayed for plant growth promotion on rhizopine producing barley lines. To test the feasibility of controlled synthetic symbiosis in a nodule environment, rhizopine control of nitrogen fixation was assayed in the model symbiotic rhizobium <em>S. meliloti</em>. …”

Elevated reactive oxygen species can drive the alternative lengthening of telomeres pathway in ATRX-null cancers by Goncalves, T, Cunniffe, S, Ma, T, Mattis, N, Rose, A, Kent, T, Mole, D, Geiller, HB, van Bijsterveldt, L, Humphrey, T, Hammond, E, Gibbons, R, Clynes, D, Rose, A

“…We also demonstrate that elevation of ROS can trigger over-activity of the ALT pathway in osteosarcoma and glioma cell lines, resulting in excessive DNA damage and cell death. …”

Physical properties of keropok (fried crisps) in relation to the amylopectin content of the starch flours by Mohamed, Suhaila, Abdullah, Norakiah, Muthu, Mangayar Karasi

“…Linear expansion, oil absorption and elasticity were positively correlated to the total amylopectin content in the whole flour (r2 = 0.99, 0.97 and 0.97 respectively). The best fitted lines for prediction of linear expansion, oil absorption and elasticity of the fried crisps were 21y ≦ 0.35x ‐ 162, y=0.15x‐ 74 and y=0.0008x‐0.41 respectively, where x is the amylopectin content of the whole flour. …”

Potential biological control agents of Geosmithia morbida restrict fungal pathogen growth via mycoparasitism and antibiosis by Onufrak, Aaron J., Gazis, Romina, Gwinn, Kimberly, Klingeman, William, Khodaei, Sima, Perez Oñate, Luis I., Finnell, Autumn, Givens, Spencer, Chen, Cristine, Holdridge, David R., Hadziabdic, Denita

“…Additionally, one metabolite-producing Trichoderma isolate, TN4-47, completely inhibited the growth of all three G. morbida isolates across all tested metabolite concentrations and had comparatively greater tolerance to juglone compared to other Trichoderma isolates. Future lines of research should focus on characterizing the active antagonistic compound present in the metabolite filtrates, determine the mode of action of the active component(s), and elucidate how abiotic and biotic factors may influence the growth, persistence, and antagonistic activity of candidate biological control agents in planta.…”
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HiTrip: Historical trajectory interpolation for trawlers via deep learning on multi-source data by Zhao, Zhongning, Chen, Jiaxuan, Shi, Yuqi, Hong, Feng, Jiang, Guiyuan, Huang, Haiguang, Zhao, Jinhua

“…One inherent challenge for precise interpolation is the stark contrast between trawler movement patterns during steaming, characterized by straight lines, and fishing, which often involves consecutive turns. …”
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Rectified and Salt Concentration Dependent Wetting of Hydrophobic Nanopores by Polster, Jake W, Aydin, Fikret, de Souza, J Pedro, Bazant, Martin Z, Pham, Tuan Anh, Siwy, Zuzanna S

“…Nanopores lined with hydrophobic groups function as switches for water and all dissolved species, such that transport is allowed only when applying a sufficiently high transmembrane pressure difference or voltage. …”
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Hypoxia-inducible factor-2 alpha up-regulates CD70 under hypoxia and enhances anchorage-independent growth and aggressiveness in cancer cells by Kitajima, Shojiro, Lee, Kian Leong, Fujioka, Masaki, Sun, Wendi, You, Jia, Chia, Grace Sushin, Wanibuchi, Hideki, Tomita, Shuhei, Araki, Marito, Kato, Hiroyuki, Poellinger, Lorenz

“…Most strikingly, we identified the emergence of CD70-expressing cells derived from CD70-negative cell lines upon prolonged hypoxia exposure or DNMT1 inhibition, both of which significantly reduced CpG-nucleotide methylations within CD70 promoter region. …”
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DevOps for Databases : A practical guide to applying DevOps best practices to data-persistent technologies / by Jambor, David, author 656261

“…Database administrators are no longer the only experts; site reliability engineers (SREs) and DevOps engineers are database experts as well. This blurring of the lines has led to increased responsibilities, making members of high-performing DevOps teams responsible for end-to-end ownership. …”
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Sequence-Dependent & -Independent Effects of Intron-Mediated Enhancement (IME) by Kowal, Emma J. K.

“…In this study we report the design and execution of several massively parallel reporter assays (MPRAs), interrogating the effect of tens of thousands of synthetic and natural intron sequences on gene expression in the human HEK293T and HeLa cell lines. We observe that even with random internal sequence, most of these introns splice well and trigger IME. …”
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Multi-criteria re-entrant jobs scheduling problems using GA and AHP by Lin, Danping.

“…The validation is conducted in two experiments, firstly single GA is implemented for the re-entrant lines and later a new combination of GA and AHP is carried out. …”
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Study of cascade failures of power grids by Ng, Jason Wei Long.

“…The substations and the transmission lines are denoted as the nodes and edges of the complex network respectively. …”
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EMS of hybrid AC/DC micro grid by Zhao, Yi

“…The issues coming along with traditional power system can be terrible for the environments, such as large use of fossil fuels, coal; long distance of transmission lines also will cause the cost of money and fuels for the electricity transmission process. …”
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Barriers and leverage points for seeing alcohol differently in integrated care systems in England: a senior stakeholder interview study by Madden, Mary, Stewart, Duncan, McCambridge, Jim

“…Results: ICS formation occurred when services had been under sustained pressures with lines of communication and accountability emergent and unclear. …”
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The role of CD1a in dengue infection by Yang, J

“…To investigate the effect of dengue infection on the function of CD1a-reactive T cells, polyclonal blood T cells from patients and controls, and CD1a-autoreactive T cells clone/lines were utilised. The production of IFN-γ and GM-CSF by CD1a-autoreactive T cells was reduced when co-cultured with dengue-infected presenting cells. …”

Development of coherent detector technologies for sub-millimetre wave astronomy observations by Tan, B-K

“…</p> <p>Using the current 16-pixel 350 GHz SIS receiver, HARP-B, we have observed the ¹²CO J=3→2 emission lines from two nearby galaxies. An important result we found is that the ¹²CO J=3→2 correlates strongly with the 8 μm Polycyclic Aromatic Hydrocarbon emission.…”