Epithelial-mesenchymal transition of cancer cells using bioengineered hybrid scaffold composed of hydrogel/3D-fibrous framework by Pal, Mintu, Chen, Huizhi, Lee, Bae Hoon, Lee, Justin Yin Hao, Yip, Yun Sheng, Tan, Nguan Soon, Tan, Lay Poh

“…In this study, we focused on two major points (i) designing and fabrication of 3D hybrid scaffolds comprising electrospun fibers with cancer cells embedded within hydrogels, and (ii) determining the potential roles of 3D hybrid scaffolds associated with EMT in cancer progression and metastasis. Our findings revealed that 3D hybrid scaffold enhances cell proliferation and induces cancer cells to undergo EMT, as demonstrated by significant up-regulation of EMT associated transcriptional factors including Snail1, Zeb1, and Twist2; and mesenchymal markers whereas epithelial marker, E-Cadherin was downregulated. …”
Get full text
Get full text

Modeling the change of beach profile under tsunami waves : a comparison of selected sediment transport models by Li, Linlin, Huang, Zhenhua

“…For real tsunamis, high suspended sediment concentration may occur, and density stratification and hindered settling effect play an important role; therefore, Delft3D, with both hindered settling and density stratification being considered, may perform better than XBeach. The findings reported here will be useful for researchers and practitioners working on tsunami hazard mitigation.…”
Get full text
Get full text

A prospective observational study comparing rates of medical instability between adolescents with typical and atypical anorexia nervosa by Brennan, Cliona, Cini, Erica, Illingworth, Sarah, Chapman, Simon, Simic, Mima, Nicholls, Dasha, Chapman, Victoria, Simms, Conor, Hayes, Ellen, Fuller, Sarah, Orpwood, Jade, Tweedy, Nicola, Baksh, Tahmida, Astaire, Emma, Bhakta, Dee, Saglio, Eloise, Stevenson, Annie, Buchbinder, Melissa

“…A significant regression equation was found for percentage median body mass index, but not rate of weight loss, as a predictor of blood pressure, serum phosphorous and magnesium. Conclusions: Our findings indicate that medical instability occurs across a range of body weights in young people with AN and AAN. …”
Get full text

Computational Fluid Dynamics (CFD) Validation and Investigation the Effect of Piston Bowl Geometries Performance on Port Fuel InjectionHomogeneous Charge Compression Ignition (PFI-... by Nik Ab Rashid, Nik Muhammad Hafiz, Hairuddin, Abdul Aziz, Md Rezali, Khairil Anas, Masuri, Siti Ujila, Abdulabbas Mossa, Al Anbagi Muntasser, Jaafar, Jamiluddin, Fitriyana, Deni Fajar

“…The piston bowl design employed in a Port Fuel Injection engine application exhibited different combustion phases while demonstrating similarity in attaining in-cylinder pressure. The findings for swirl induce piston bowl design indicate an enhancement of in-cylinder pressure for the Spiral Crown geometry model, reaching 9.42 MPa. …”
Get full text

Green roof thermal performance of small-scale prototype using IES-VE simulation in tropical climatic condition by Md Yacob, Mohamad Norfekry, Kasmin, Hartini, Siti Nazahiyah Rahmat, Siti Nazahiyah Rahmat, Tukimat, Nurul Nadrah Aqilah, Ahmad Nazri, Mohd Ariff

“…Simulation using IES-VE approved that green roofs can potentially reduce indoor temperatures, demonstrating their suitability for tropical regions. These findings have significant implications for sustainable building design and urban planning in hot and humid climates.…”
Get full text
Get full text

Green synthesis and photocatalytic insights: A review of zinc oxide nanoparticles in wastewater treatment by Hussain, Rabia Tasaduq, Hossain, Md Sanower, Jun Haslinda, Shariffuddin

“…This review summarized current scientific findings based on both unmodified and modified ZnONPs, primarily synthesized using plant sources as reducing and capping agents. …”
Get full text
Get full text

Decarbonizing airport using solar and wind farm: A case of Biratnagar, Nepal by Yadav, Bharosh Kumar, Yadav, Ramhit, Jahangiri, Mehdi, Priya, S. Shanmuga, Bajracharya, Tri Ratna, Sudhakar, Kumarasamy

“…The combined 15 kW wind turbine-grid scenario is superior to the grid scenario for wind speeds of more than nine m/s and interest rates of less than 10 %. These findings increase airport authorities' and stakeholders' confidence in the investment in greener airports.…”
Get full text

Superhydrophobic surface of Ti6Al4V using direct nanosecond laser texturing by Mohd Harizan, Zul, Mahadzir, Ishak, Aiman, Mohd Halil, Ramdziah, Md Nasir, Moinuddin, Mohammed Quazi

“…Laser texturing techniques successfully improved surface roughness and profile, facilitating the development of superhydrophobic surfaces. These findings offer valuable insights for advancing surface engineering, with potential applications in the aerospace, automotive, and biomedical industries.…”
Get full text

Financial technology readiness for Shariah-compliant banking services: Post-merger perspectives by Kurniawati, Desi Tri, Fernando, Yudi, M. Abdi Dzil, Ikhram W., Masyhuri, .

“…The data were then analysed using PLS-SEM with SmartPLS software. Findings: Perceived organisational support became crucial in improving readiness to adopt the digitalisation initiative and adhere to Shariah norms. …”
Get full text
Get full text

Battery remaining useful life estimation based on particle swarm optimization-neural network by Zuriani, Mustaffa, Mohd Herwan, Sulaiman

“…Upon examination of the findings, it becomes evident that the PSO NN model outperforms the alternatives with an MAE of 2.7708 and an RMSE of 4.3468, significantly lower than HSA-NN (MAE: 22.0583, RMSE: 34.5154), CA-NN (MAE: 9.1189, RMSE: 22.4646), and ARIMA (MAE: 494.6275, RMSE: 584.3098). …”
Get full text

Thermal and flow characteristics of alumina nanofluids in microfluidic systems: A low-concentration study by Samylingam, Lingenthiran, Aslfattahi, Navid, Kadirgama, Kumaran, Ramasamy, Devarajan, Kok, Chee Kuang, Norazlianie, Sazali, Wan Sharuzi, Wan Harun, Nor Atiqah, Zolpakar, Mohd Fairusham, Ghazali

“…The study concludes that low-concentration Al₂O₃ nanofluids can enhance thermal performance in microfluidic systems without significantly affecting flow characteristics, making them suitable for applications requiring efficient heat dissipation, such as electronic cooling and chemical reactions. These findings provide a foundation for future research into higher nanoparticle concentrations and different base fluids, aimed at optimizing the thermal and flow properties of nanofluids in microfluidic environments. …”
Get full text

Stereospecific α-glucosidase inhibition, kinetics, and molecular docking studies on isolated diastereomeric alkaloids from Uncaria longiflora by Nurul Aina Suzlin, Sulaiman, Muhammad Farhan Syakir, Nor Azman, Mohd Fadhlizil Fasihi, Mohd Aluwi, Zainul Amiruddin, Zakaria, Mohammad Jemain, Mohammad Ridhwana, Fatimah, Salim

“…Although the high concentrations required for effective enzyme inhibition may limit the practical application of these compounds as antidiabetic therapies, this study provides valuable insights into the chemistry underlying the plant’s previously reported antidiabetic potential, particularly in a stereospecific context. The findings further support the unique biological activities attributed to the diastereomeric alkaloids, highlighting their importance in understanding the plant’s therapeutic potential.…”
Get full text

Water surge risk mapping using GIS-based spatial multi-criteria decision analysis approach by Syarifuddin, Misbari, Siti Sarah, Abd Razak, Muhammad Fuad Fahmi, Jaafar, Nadiatul Adilah, Ahmad Abdul Ghani, Mohd Faizal, Jamlos

“…A water surge risk map is developed by not only visualizing water surge factors but also weighting each relevant contributing factor, such as terrain elevation, land use type, and rainfall. The finding of the study suggests that Sg. Pandan Waterfall area falls into medium-risk water surge zones due to combination of three main factors including terrain elevation, land use or rainfall pattern. …”
Get full text

Coloration and functionalization of organic cotton fabric using Chinese fringe leaf extraction: A greener approach by Hossain, Md Shazzat, Ullah, Mohammad, Mia, Rony, Assiri, Mohammed Ail, Zhou, Yahui, Saeed, Haroon A.M., Mahmud, Sakil

“…This research highlights the potential of Chinese fringe leaf extracts for eco−friendly coloration and functional enhancement of OCF. The findings have significant implications for the textile industry, offering a path towards more environmentally responsible manufacturing practices without compromising on performance or aesthetics.…”
Get full text

Camel Milk and Oxidative stress: Therapeutic potential against metabolic syndrome diseases by Musa, Khalid Hamid, Hamad, Essam M., Elnour, Ahmed Adam Hassan Mohammed

“…Methods: A comprehensive literature review was conducted focusing on studies that explored the antioxidant properties of CM and its impact on OS and metabolic syndrome. Results: The findings indicated that CM possesses significant antioxidant properties, mainly attributed to its bioactive compounds, which can inhibit the production of various reactive oxygen species (ROS), thereby reducing OS. …”
Get full text

Analysis of brain tissue poroelastic properties using multiscale modelling by Abbas, Shabudin, Mohd Jamil, Mohamed Mokhtarudin, Nik Mohd Zuki, Nik Mohamed, Mohd Akramin, Romlay

“…Hence, important properties of the capillary, including shape and size, should be carefully emphasized so that accurate findings can be obtained when solving the poroelastic model of the brain…”
Get full text

Integrative multi-omics dissection of cancer cell states and susceptibility by Liu, Yunpeng(Biologist)Massachusetts Institute of Technology.

Get full text

Centering Patient and Clinician Voices in Developing Tools to Address Pain Related School Impairment: A Phase I Study of a Virtual Reality School Simulation for Children and Adoles... by Logan, Deirdre E., Khanna, Karina, Randall, Edin, O’Donnell, Shealyn, Reks, Talis, McLennan, Logan

“…Qualitative feedback from both groups identified positive aspects of vRS, including finding the simulation realistic and easy to use and offering ways to address school functioning goals that are not otherwise feasible in the IIPT setting. …”
Get full text

New challenges in oxygen reduction catalysis: a consortium retrospective to inform future research by Stevens, Michaela Burke, Anand, Megha, Kreider, Melissa E., Price, Eliza K., Zeledón, José Zamara, Wang, Liang, Peng, Jiayu, Li, Hao, Gregoire, John M., Hummelshøj, Jens, Jaramillo, Thomas F., Jia, Hongfei, Nørskov, Jens K., Roman-Leshkov, Yuriy, Shao-Horn, Yang, Storey, Brian D., Suram, Santosh K., Torrisi, Steven B., Montoya, Joseph H.

“…However, we also hope to illustrate both the potential impact of a collaborative strategy with the hopes of inspiring a higher degree of Industry-Academia-National Laboratory collaboration and encourage other centers and consortiums to distill and share their findings in a similar perspective-type article. Together we hope to enable the fuel cell research community to engage in a discussion of strategies for research and accelerated development of catalysts with improved activity and stability.…”
Get full text

The Architectural Layout of Long-Term Care Units: Relationships between Support for Residents’ Well-Being and for Caregivers’ Burnout and Resilience by Rom, Yifat, Morag, Ido, Palgi, Yuval, Isaacson, Michal

“…Layouts supporting social well-being showed inconsistent correlations with caregivers’ resilience indexes in dementia units, and with burnout and resilience indexes in regular nursing units. The findings underscore the role of the architectural layout of long-term care units in enhancing residents’ well-being; the results also highlight the possible unintentional yet negative impact of the layout on the caregivers’ burnout and resilience. …”
Get full text