A loss-of-function mutation in KCNJ11 causing sulfonylurea-sensitive diabetes in early adult life by Vedovato, N, Salguero, MV, Greeley, SAW, Yu, CH, Philipson, LH, Ashcroft, FM

“…In this case, the patient may have had hyperinsulinism that escaped detection in early life. Our results support the importance of functional analysis of K_ATP channel mutations in cases of atypical diabetes.…”

Rewilding in Southeast Asia: Singapore as a case study by Lamperty, Therese, Chiok, Wen Xuan, Khoo, Max D. Y., Amir, Zachary, Baker, Nick, Chua, Marcus A. H., Chung, Yi Fei, Chua, Yen Kheng, Koh, Joshua J.-M, Lee, Benjamin P. Y.-H., Lum, Shawn K. Y., Mendes, Calebe P., Ngiam, Jonathan, O Dempsey A., Png, Kenny G. C., Sovie, Adia R., Tan, Lorraine, Teo, Robert, Thomas, Noel, Li, Tianjiao, Lim, Bryan Tze-Ming, Loo, Adrian H. B., Wardle, David A., Luskin, Matthew Scott

“…Sambar deer (Rusa unicolor) escaped from captivity (in private or public zoos) in the 1970s and contemporary camera trap data show they have only colonized nearby forest fragments and their abundance remains low. …”
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Assessing the financial performance of container shipping companies by Cai, Kewei

“…Over the past few decades, a phenomenon was observed where container shipping lines are adapting vertical integration strategies towards the ports and logistics market, which is outside of their core business. …”
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Pro-inflammatory feedback loops define immune responses to pathogenic Lentivirus infection by Wilk, Aaron J., Marceau, Joshua O., Kazer, Samuel W., Fleming, Ira, Miao, Vincent N., Galvez-Reyes, Jennyfer, Kimata, Jason T., Shalek, Alex K., Holmes, Susan, Overbaugh, Julie, Blish, Catherine A.

“…Conversely, individual cells infected with highly pathogenic Lentivirus upregulated fewer interferon-stimulated genes at a lower magnitude, indicating that highly pathogenic Lentivirus has evolved to partially escape from interferon responses. Further, we identify CXCL10 and CXCL16 as important molecular drivers of inflammatory pathways specifically in response to highly pathogenic Lentivirus infection. …”
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Protein Folding, Host Cell Proteostasis, and Viral Evolution by Yoon, Jimin

“…Second, I focus on an important immune-escape variant of influenza nucleoprotein whose fitness depends on host chaperones, and reveal the underlying molecular mechanism of the chaperon dependence. …”
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SARS-CoV-2 evolution during treatment of chronic infection by Kemp, SA, Collier, DA, Datir, RP, Ferreira, IATM, Gayed, S, Jahun, A, Hosmillo, M, Rees-Spear, C, Mlcochova, P, Lumb, IU, Roberts, DJ, Chandra, A, Temperton, N, Sharrocks, K, Blane, E, Modis, Y, Leigh, KE, Briggs, JAG, van Gils, MJ, Smith, KGC, Bradley, JR, Smith, C, Doffinger, R, Ceron-Gutierrez, L, Barcenas-Morales, G, Pollock, DD, Goldstein, RA, Smielewska, A, Skittrall, JP, Gouliouris, T, Goodfellow, IG, Gkrania-Klotsas, E, Illingworth, CJR, McCoy, LE, Gupta, RK

“…As passively transferred serum antibodies diminished, viruses with the escape genotype were reduced in frequency, before returning during a final, unsuccessful course of convalescent plasma treatment. …”

A study of human monoclonal antibodies to influenza and ebola viruses by Rijal, P

“…Monoclonal antibodies isolated from such focused responses selected escape mutations <em>in vitro</em> that matched actual antigenic drift observed in circulating viruses. …”

The chronic cerebral hypoperfusion model induces proinflammatory cascades in Alzheimer's disease by Abedi, Zahra, Basri, Hamidon, Hassan, Zurina, Inche Mat, Liyana Najwa, Khaza’ai, Huzwah, Mohd Ali, Razana

“…Structural damage to the hippocampus was assessed using hematoxylin and eosin (HE) staining. Escape latencies and time spent in specific quadrants in PBOCCA significantly increased compared to sham-operated animals. …”
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Developing a Positive Psychology Principles Based on Social Media Utilization Among Housewives (S/O 13751) by Abdul Hamid, Norsiah, Ishak, Mohd Sobhi, Mohd Rashid, Sabrina

“…Five motives have been proposed namely Escapism, Information Seeking, Friendship Maintenance, Relationship Initiation, and Nostalgia, which were then tested for with Well-being and Flourishing. …”
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Developing a lightscape application (using a raspberry PI) by Ong, Wenchuan

“…The project aims to develop a web application, which will be hosted within the Raspberry Pi, for controlling the brightness of constant light source from the high power LED via the Raspberry Pi’s General Purpose Input Output (GPIO) pins and gather optimal settings for projecting images with the Light Blaster. …”
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Additive friction stir processing by Lin, Longyi

“…The continuous dynamic recrystalisation during FSP also gave finer grains, which was further enhanced with the addition of CNTs through Zener pinning effect. The improvement in tensile strengths due to finer grains through the Hall-Petch mechanism was insufficient to compensate for the drop in Orowan strengthening. …”
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Singapore boreholes results with numerical and analytical simulation by Yap, Kai Xian

“…To achieve this, the final year project outlined in this report will leverage advanced computer software to simulate various tunnel lining designs across different soil profiles specific to Singapore. …”
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Small spherical and projective codes by Cohn, Henry

“…This data set describes the best spherical and real projective codes that are known to exist (to the best of my knowledge), for up to 32 points on spheres or 16 lines through the origin in the real projective case. …”
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Humanity's dark side: coping with a failing world order by John, Lord Alderdice

“…Various crises have exposed fault-lines in the existing global order. It has spotlighted the existing differences in ideologies across the world. …”
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The chronicles of cerebrovascular aging: an epic transcriptomic tale by Nguyen, Le Uyen Nhi

“…Endothelial cells are the lining of blood vessels, these cells play a crucial role in maintaining vascular integrity. …”
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Entrepreneurship in shipping industry : study of overseas Chinese entrepreneurship, and the influence of social network and family control. by Chen, Tian.

“…This dissertation is a case study regarding overseas Chinese entrepreneurship, it was based on the study of Pacific International Lines. The core of this dissertation is to study entrepreneurship of PIL founder. …”
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Driving towards inspection 4.0 for FMCG industry by Quek, Jaime Li-Lyn

“…Hence, this report will focus on discussing how industry 4.0 inspection techniques can be applied within FMCG production lines, as well as cover the potential gaps and challenges when implementing the solutions…”
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Modelling and optimization of micro optofluidic lenses by Song, Chaolong, Nguyen, Nam-Trung, Tan, Say-Hwa, Asundi, Anand Krishna

“…The lens shape as well as the stream lines were characterized using fluorescent dye and tracing particles. …”
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Stable transformation of pleomorphic bloodstream form Trypanosoma brucei by MacGregor, P, Rojas, F, Dean, S, Matthews, KR

“…This permits routine genetic manipulation of pleomorphic lines, which have the most biological relevance for trypanosomes in the field.…”

The struggle for Syria : Iran-Qatar ties come under stress by James M. Dorsey

“…The struggle by Syrian opposition forces to topple the Assad regime is sharpening tensions between Iran and Qatar and threatens sectarian fault lines elsewhere in North Africa and Middle East. …”
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