DRD-UNet, a UNet-like architecture for multi-class breast cancer semantic segmentation by Ortega-Ruíz, Mauricio Alberto, Karabağ, Cefa, Roman-Rangel, Edgar, Reyes-Aldasoro, Constantino Carlos

“…This paper describes a UNet-like deep learning architecture called DRD-UNet, which adds a novel processing block called DRD (Dilation, Residual, and Dense block) to a UNet architecture. …”
Get full text

Recombinant expression systems for production of stabilised virus-like particles as next-generation polio vaccines by Sherry, L, Bahar, MW, Porta, C, Fox, H, Grehan, K, Nasta, V, Duyvesteyn, HME, De Colibus, L, Marsian, J, Murdoch, I, Ponndorf, D, Kim, S, Shah, S, Carlyle, S, Swanson, JJ, Matthews, S, Nicol, C, Lomonossoff, GP, Macadam, AJ, Fry, EE, Stuart, DI, Stonehouse, NJ, Rowlands, DJ

“…Continued use of these vaccines, however, threatens ultimate disease eradication and achievement of a polio-free world. Virus-like particles (VLPs) that lack a viral genome represent a safer potential vaccine, although they require particle stabilization. …”

Bacteriocin-like peptides encoded by a horizontally acquired island mediate Neisseria gonorrhoeae autolysis by Poncin, K, McKeand, SA, Lavender, H, Kurzyp, K, Harrison, OB, Roberti, A, Melia, C, Johnson, E, Maiden, MCJ, Greaves, DR, Exley, R, Tang, CM

“…The nap island in the gonococcus encodes 3 cationic, bacteriocin-like peptides which have no detectable antimicrobial activity. …”

Distinct movement disorders in contactin-associated-protein-like-2 antibody-associated autoimmune encephalitis by Gövert, F, Abrante, L, Becktepe, J, Balint, B, Ganos, C, Hofstadt-van Oy, U, Krogias, C, Varley, J, Irani, SR, Paneva, S, Titulaer, MJ, de Vries, JM, Boon, AJW, Schreurs, MWJ, Joubert, B, Honnorat, J, Vogrig, A, Ariño, H, Sabater, L, Dalmau, J, Scotton, S, Jacob, S, Melzer, N, Bien, CG, Geis, C, Lewerenz, J, Prüss, H, Wandinger, K-P, Deuschl, G, Leypoldt, F

“…In the elderly, anti-LGI1 and contactin associated protein like 2 (CASPR2) antibody-associated diseases compose a relevant fraction of autoimmune encephalitis. …”

Antimicrobial efficacy testing of antibiotic-containing biodegradable nanopolymers against biofilm and planktonic cells. by Polimyr Caesar Dave Pelisco Dingal.

Get full text

The cellular characterization of SARS-CoV-2 spike protein in virus-infected cells using the receptor binding domain binding specific human monoclonal antibodies by Chan, Conrad En-Zuo, Ng, Ching-Ging, Lim, Angeline Pei-Chew, Seah, Shirley Lay-Kheng, Chye, De-Hoe, Wong, Steven Ka-Khuen, Lim, Jie-Hui, Lim, Vanessa Zi-Yun, Lai, Soak-Kuan, Wong, Pui-San, Leong, Kok-Mun, Liu, Yi-Chun, Sugrue, Richard J., Tan, Boon Huan

“…While all five antibodies bound conformational-specific epitopes within SARS-CoV-2 spike (S) protein, only PD5, PD7, and SC23 were able to bind to the receptor binding domain (RBD). …”
Get full text

Enriching the methanol generation via CO2 photoconversion over the cockscomb-like fibrous silica copper by Mahadi, Bahari, Che Rozid, Mamat, Aishah, Abdul Jalil, Shing, Lo Sook, Nurul Sahida, Hassan, F. F.A., Aziz, Alhassan, Mansur, Mohd Ghazali, Mohd Nawawi, Kamarizan, Kidam, Herma Dina, Setiabudi

Get full text
Get full text

Toward a crystal-clear view of the viral RNA sensing and response by RIG-I-like receptors by Luo, Dahai

“…The RIG-I-like receptors (RLRs)—RIG-I, MDA5, and LGP2—detect intracellular pathogenic RNA and elicit an antiviral immune response during viral infection. …”
Get full text
Get full text

Persistent elevation of intrathecal pro-inflammatory cytokines leads to multiple sclerosis-like cortical demyelination and neurodegeneration by James, Rachel E., Schalks, Renee, Browne, Eleanor, Eleftheriadou, Ioanna, Munoz, Carmen Picon, Mazarakis, Nicholas D., Reynolds, Richard

“…Here we tested the hypothesis that persistent production of these cytokines in the meningeal compartment and diffusion into underlying GM can drive chronic MS-like GM pathology. Lentiviral transfer vectors were injected into the sagittal sulcus of DA rats to deliver continuous expression of TNF + IFNγ transgenes in the meninges and the resulting neuropathology analysed after 1 and 2 months. …”
Get full text

Chrysanthemum-like Au@Polydopamine synthesized using one-pot method and its advantage in immunochromatographic assay by Zhang, Gang-gang, Lai, Xiao-cui, Ding, Neng-shui, Xiong, Qirong, Hou, Shuai, Duan, Hongwei, Lai, Wei-hua

“…Flower-like gold nanoparticle (AuNF) is widely used as a probe. …”
Get full text

Functional characterization of plasmodium falciparum reticulocyte binding like protein homologue 1 (PfRH1) by Yap, Sally Shu Lin

“…One of the protein families involved in invasion, reticulocyte binding like protein homologues (PfRHs) has been suggested to be involved in host cell selection. …”
Get full text

Genes for carnivory : a comparative study on the local duplication of papain-like cysteine proteases in carnivorous plants by Tan, Qiao Wen

“…Thus, the presence of protein degrading enzymes such as papain-like cysteine proteases (PLCPs) in trap fluids is not surprising. …”
Get full text

Bio-inspired Flow Sensing and Prediction for Fish-like Undulating Locomotion: A CFD-aided Approach by Zhou, Han, Hu, Tianjiang, Low, Kin Huat, Shen, Lincheng, Ma, Zhaowei, Wang, Guangming, Xu, Haijun

Get full text
Get full text

Functional comparison of human Adenomatous Polyposis Coli (APC) and APC-like in targeting beta-catenin for degradation by Schneikert, Jean, Chandra, Shree Harsha Vijaya, Ruppert, Jan Gustav, Ray, Suparna, Wenzel, Eva Maria, Behrens, Jürgen

“…Using RNA interference and domain swapping experiments, we show that APCL benefits from the 15R of truncated APC to target β-catenin for degradation, in a process likely involving heterodimerization of the two partners. …”
Get full text
Get full text

Local rainfall is more likely than distant thunderstorms to affect movement behaviour in Northern Kenyan elephants by Mulder, T, Mortimer, B, Ferwerda, J, Vollrath, F

“…We conclude that climate change makes a strong case for studying elephant behaviours in response to environmental cues during the day and night, especially in dry-land study sites like Northern Kenya.…”

GOLDEN2-like1 is sufficient but not necessary for chloroplast biogenesis in mesophyll cells of C4 grasses by Lambret-Frotte, J, Smith, G, Langdale, J

“…In land plants, chloroplast biogenesis is regulated by a family of transcription factors named GOLDEN2-like (GLK). In C4 grasses, it has been hypothesized that genome duplication events led to the sub-functionalization of GLK paralogs (GLK1 and GLK2) to control chloroplast biogenesis in two distinct cell types: mesophyll and bundle sheath cells. …”

Characterization on three-dimensional trajectory of disk-like gold-nickel-platinum nanomotor using digital holographic imaging by Hu, Liangxing, Rehman, Shakil, Tao, Kai, Miao, Jianmin

Subjects: Get full text
Get full text

Ligand-specific factors influencing GLP-1 receptor post-endocytic trafficking and degradation in pancreatic beta cells by Fang, Zijian, Chen, Shiqian, Manchanda, Yusman, Bitsi, Stavroula, Pickford, Philip, David, Alessia, Shchepinova, Maria M., Corrêa, Ivan R., Jr., Hodson, David J., Broichhagen, Johannes, Tate, Edward W., Reimann, Frank, Salem, Victoria, Rutter, Guy A., Tan, Tricia, Bloom, Stephen R., Tomas, Alejandra, Jones, Ben

Subjects: Get full text

Effect of solvent state and isothermal conditions on gelation of methylcellulose hydrogels by Joshi, Sunil Chandrakant, Liang, C. M., Lam, Yee Cheong

Subjects: Get full text
Get full text

Steady spinning of synthetic silk-like fibers and transient filament stretching of semi-dilute and concentrated polymeric fluids by Brauner, Octavia Flora, 1975-

Get full text