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2401
Antitumor polycyclic acridines. 7. Synthesis and biological properties of DNA affinic tetra- and pentacyclic acridines
Published 2000“…The novel water-soluble agent dihydroindolizino[7,6,5-kl]acridinium chloride 14 has inhibitory activity in a panel of non-small-cell lung and breast tumor cell lines exceeding that of m-AMSA. The salt inhibited the release of minicircle products of kDNA confirming that disorganization of topoisomerase II partly underlies the activity of the compound. …”
Article -
2402
Cellular reporter for inflammation.
Published 2011“…Currently, there are commercial green fluorescent protein (GFP) assays available for in vitro cell lines only. There are no in vivo systems that can report NF-B activation in hematopoietic stem cells. …”
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Final Year Project (FYP) -
2403
Laser surface treatment of 50CrMo4 steel
Published 2018“…The speed of laser is significance in affecting the width and depth of the laser treated lines. When the speed is too high, the change is not visible, thus, the hardness test cannot be done on the cross section area.…”
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Final Year Project (FYP) -
2404
Database and Application Programming Interface Development for Rotational Spectroscopy
Published 2024“…A database of spectroscopic data serves as the foundation of the automation pipeline for assigning spectral lines to species. While there are existing databases available for use, we developed our custom database, named SAAGAdb, and an application programming interface (API) to access the database to fulfill the needs of SAAGA. …”
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Thesis -
2405
Cytotoxic triosmium carbonyl clusters : a structure-activity relationship study
Published 2014“…In vitro evaluation of these new compounds showed that some are selectively active against estrogen receptor (ER)-independent MDA-MB-231 breast cancer cell lines relative to ER-dependent MCF-7 breast cancer cells, suggesting that the compounds have a different biological target specific to MDA-MB-231 cells. …”
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Journal Article -
2406
An iGlu receptor antagonist and its simultaneous use with an anticancer drug for cancer therapy
Published 2015“…In vitro studies on B16F10 and NIH3T3 cell lines revealed that the iGlu receptor antagonist L1 exhibited therapeutic as well as targeting effects. …”
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Journal Article -
2407
Investigating the content and function of stress-induced extracellular vesicles in colorectal cancer
Published 2021“…Therefore, my DPhil focussed on investigating the potential pro-tumorigenic properties of these “switched” EVs in CRC cell lines in vitro and also assessing the composition of EVs in CRC patient plasma.…”
Thesis -
2408
Neuroprotective effect of tocotrienol-rich fraction and a-tocopherol of vitamin E against glutamate toxicity in neuronal cells and astrocytes
Published 2015“…In this study, the effects of vitamin E when supplemented before (pre-treatment) and after (post-treatment) glutamate insult were elucidated in neuronal and astrocyte cell lines. The neuroprotective effect of TRF and α-TCP were investigated. …”
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Thesis -
2409
Challenges and applications to operando and in situ TEM imaging and spectroscopic capabilities in a cryogenic temperature range
Published 2022“…Such studies are promising for studying the pinning of the ferroelectric and magnetic domains versus temperature, spin-polarized current, and externally applied magnetic field to better manipulate the domain walls. …”
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Journal Article -
2410
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2411
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2412
Incentivizing consensus propagation in proof-of-stake based consortium blockchain networks
Published 2020Get full text
Journal Article -
2413
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2414
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2415
Moho complexity in Southern California revealed by local PmP and teleseismic Ps waves
Published 2022Get full text
Journal Article -
2416
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2417
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2418
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2419
Acidic corrosion behaviour of niobium-added welding overlays fabricated by self-shielded metal-cored wires
Published 2024Get full text
Journal Article -
2420
Deep neural network technique for automated detection of ADHD and CD using ECG signal
Published 2024Get full text
Journal Article