Culture of human pluripotent stem cells and neural networks in 3D using an optogenetic approach and a hydrogel model by Lee, S

“…Investigation of cell response reveals that a flow rate of 3 ml/min and an alginate concentration of 1.8% (w/v) are optimal and that stem cell survival is significantly improved through incorporation of RGD and ROCKi. …”

Multi-colony coral skeletal Ba/Ca from Singapore’s turbid urban reefs : relationship with contemporaneous in-situ seawater parameters by Tanzil, Jani Thuaibah Isa, Goodkin, Nathalie Fairbank, Sin, T. M., Chen, Mengli, Fabbro, Gareth Nicholas, Boyle, E. A., Lee, A. C., Toh, K. B.

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Electrospun carbon-silica composite nanofibers for selective removal of oil and water by Tai, Ming Hang

“…After surface-coating with silicone oil for 30 min, the composite membrane exhibited ultra-hydrophobic and superoleophilic properties with water and oil contact angles being 144.2 ± 1.2° and 0°, respectively. …”
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Chronic oxidative stress promotes GADD34-mediated phosphorylation of the TAR DNA-binding protein TDP-43, a modification linked to neurodegeneration by Goh, Catherine Wenhui, Lee, Irene Chengjie, Sundaram, Jeyapriya Rajameenakshi, George, Simi Elizabeth, Yusoff, Permeen, Brush, Matthew Hayden, Sze, Newman Siu Kwan, Shenolikar, Shirish

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Establishment of optimise strategies in production of recombinant Hepatitis B surface antigen for chip-based antibody detection approach by Tam, Yew Joon

“…The main results drawn showed that the IEC Q Sepharose XL column and optimum conditions of 4 mL sample loading volume, an elution buffer with 1.5 M NaCl concentration at pH 8 with an elution gradient length of 20 column volume and subsequent purification with SEC at a sample volume of 5 mL and a flow rate of 1 mL/min was able to efficiently purify HBsAg. An up-scaled version the established purification strategy comprising of the two techniques further demonstrated adaptability for scale-up operations with a final total PF of 94.82 ± 16.20, HBsAg purity of 95.48% and recovery yield of 78.07%. …”
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Design of digital-intensive time-mode data converters based on delay correction utilising a time-to-digital converter by Kong, Junjie

“…Of the two TDCs, the Coarse-Fine TDC has a high resolution of 1.08 ps, and a sampling frequency of 278 MHz and consumes a relatively lower power of 1.8 mW. …”
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Towards haptic intelligence in robots by learning from demonstration by Turlapati Sri Harsha

“…In the first part of this thesis, we build on this latter idea of performing haptic exploration of surfaces with a focus on extracting the geometry of fine features. We propose a novel quantity, haptic mismatch that identifies and refines missing geometric features based on the discrepancy in force feedback from actual interactions with an object. …”
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Investigation on the role of Sb doping on grain growth and properties of solution-processed CuIn(S,Se)2 by Ho, John Chun Wan

“…The resultant film is dense and uniform but has very fine grains which are detrimental to carrier transport. …”
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Dysregulation of the Pdx1/Ovol2/Zeb2 axis in dedifferentiated β-cells triggers the induction of genes associated with epithelial-mesenchymal transition in diabetes by de Jesus, Daniel S., Mak, Tracy C. S., Wang, Yi-Fang, von Ohlen, Yorrick, Bai, Ying, Kane, Eva, Chabosseau, Pauline, Chahrour, Catherine M., Distaso, Walter, Salem, Victoria, Tomas, Alejandra, Stoffel, Markus, Rutter, Guy A., Latreille, Mathieu

“…We carried out loss- and gain-of-function experiments in MIN6 and EndoC-bH1 cell lines. We analysed previously published mouse andhuman T2D data sets.Results:Bulk RNA-seq revealed thatb-cell dedifferentiation is associated with the induction of genes associated with epithelial-to-mesenchymal transition (EMT) in prediabetic (2-week-old) and diabetic (12-week-old) Tg7 mice. …”
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大时代小人物的命运: 论新加坡教育改革下华校师生对语言的情意结 = Fate of individuals in a revolutionary era: a study on the language attachment of Chinese school teachers and students under Singapore's education... by 李瑞君 Lee, Rui Jun

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Conformational design characterization of a truncated diamine oxidase by Razali, Nur Nadia

“…By maintaining the native protein’s pH profile, the mini protein was highly active at 40 °C and stable at pH 7, with a half-life of 80 min at 50 °C. Results from the kinetic studies showed that the Km value for native diamine oxidase was 0.274 mM and 1.3 mM for the mini protein. …”
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Tropical peat subsidence, nutrient losses and oil palm seedling growth due to different water table depths by Abubakar, Safiyanu Hashim

“…The system was made of exchange chamber of air pump with the flow rate ranges between 1 and 3.5 L min-1, exchange chamber of (2670 mL plastic container) and a trap (250 mL Erlenmeyer flask). …”
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Stability improvement and control optimization of isolated two-stage AC-DC-DC converter systems by Feng, Fan

“…The analysis results offer instructive implications to fine-tune the design rules of the DAB converters. …”
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Enhancing tensile and fatigue properties of additively manufactured alloys by post-processing heat treatment by Radhakrishnan, Jayaraj

“…LB-PBF process results in a fine hierarchical microstructure which can impart a simultaneous enhancement of strength and fracture toughness. …”
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HiPIMS deposition of VO2 thermochromic coating for enhanced optical properties by Vu, Tuan Duc

“…In chapter 4, a HiPIMS deposition technique for VO2(M) thin film on a commercial material, such as soda-lime glass substrate, was established with a high deposition rate of 5.7 nm/min. The VO2(M) deposited on soda-lime glass exhibits excellent crystallinity and thermochromic properties (highest luminous transmission Tlum ≈ 30.4%, and solar modulation ΔTsol ≈ 12%) in comparison with similarly prepared VO2 on high temperature glass and quartz substrates. …”
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Evaluation of paper spray mass spectrometry for direct analysis of small molecule drugs and hemoglobin constant spring peptide markers by Takyi-Williams, John

“…Further application of the PS-MS assay to preclinical pharmacokinetic (PK) study found that, the assay was simple and rapid with overall analysis time of 1 min and a full plasma concentration vs. time profile of sunitinib could be obtained from a single mouse. …”
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Antimicrobial activity, phytochemical and toxicity analyses of salam [Syzygium polyanthum (Wight) Walp.] leaf extract and its application in food by Ramli, Suzita

“…Generally the significant reduction of natural microflora in tested food samples were started at 0.50% (v/v) of extract at 5 min. During storage, 5% (v/v) showed better effect in controlling the microbial survival throughout the storage time. …”
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Uncertainty quantification framework for combined statistical spatial downscaling and temporal disaggregation for climate change impact studies on hydrology by Rajendran Queen Suraajini

“…Thus, the strategies to assist future adaption planning and risk mitigation during extreme flood events need to be developed based on the predicted future climate conditions. Fine spatial and temporal resolutions in climate data are needed to simulate the change in future flood events and to study the climate change impact on hydrology. …”
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The prospective associations of 24-hour movement behaviors and domain-specific activities with executive function and academic achievement among school-aged children in Singapore by Padmapriya, Natarajan, Bernard, Jonathan Y., Tan, Sarah Yi Xuan, Chu, Anne H. Y., Goh, Claire Marie Jie Lin, Tan, Shuen Lin, Shek, Lynette P., Chong, Yap Seng, Tan, Kok Hian, Chan, Shiao-Yng, Yap, Fabian, Godfrey, Keith M., Lee, Yung Seng, Meaney, Michael J., Eriksson, Johan G., Tan, Chuen Seng, Law, Evelyn C., Müller-Riemenschneider, Falk

“…However, higher moderate-to-vigorous PA (MVPA) relative to remaining movement behaviors at age 5.5 years was associated with lower academic achievement [Mean difference (95% confidence interval): −0.367 (−0.726, −0.009) z-score], and reallocating MVPA time to sleep showed higher academic achievement scores [30 min from MVPA to sleep: 0.214 (0.023, 0.404) z-score]. …”
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Energy storage management for renewable energy systems by Feng, Xue

“…The device models including the dynamic battery model proposed are incorporated in the system simulations. A fine-grained intelligent control strategy with multiple operation modes is designed to distribute the power demand between the batteries and the ultracapacitors considering the real time power mismatches. …”
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