Single cell hydrodynamic stretching and microsieve filtration reveal genetic, phenotypic and treatment-related links to cellular deformability by Li, Fenfang, Cima, Igor, Vo, Jess Honganh, Tan, Min-Han, Ohl, Claus-Dieter

“…We show that colorectal cancer cell line RKO with the mesenchymal-like feature is more flexible than the epithelial-like HCT116. …”
Get full text

Cluster-based information fusion for probabilistic risk analysis in complex projects under uncertainty by Zhang, Limao, Wang, Ying, Wu, Xianguo

“…The developed approach is used to assess the water leakage condition of Line 2 of the Wuhan metro system in China to demo its feasibility. …”
Get full text

Increased interleukin-6 correlates with myelin oligodendrocyte glycoprotein antibodies in pediatric monophasic demyelinating diseases and multiple sclerosis by Horellou, P, Wang, M, Keo, V, Chrétien, P, Serguera, C, Waters, P, Deiva, K

“…MOG antibody titers in plasma were tested by flow cytometry using a stable cell line expressing full-length human MOG. We found a significant increase in C5a levels in the CSF of patients with monophasic ADS (n=17) compared to OND (n=12, p=0.0036) and to MS (n=17, p=0.0371). …”

A transgenic zebrafish for in vivo visualization of cilia by Zhang, Hongyu, Huang, Zhuoya, Lv, Liuliu, Xin, Yuye, Wang, Qian, Li, Feng, Dong, Lina, Wu, Changxin, Ingham, Philip William, Zhao, Zhonghua

“…Due to the lack of a conserved, short ciliary localization motif, the full-length ARL13b or 5HT6 proteins are normally used for cilia labelling. …”
Get full text

Bolstering functionality in multilayer and bilayer WS₂ via focused laser micro-engraving by Chan, Si Min, Poh, Eng Tuan, Leong, Jin Feng, Goh, Johnson Kuan Eng, Sow, Chorng Haur

“…Coupled with the flexible maneuver of the laser, various monolayer designs can be achieved, including micro-antenna, waveguide, and electrode geometries with lateral line widths at 1.5 µm resolution. Furthermore, we also detail the optical properties of the monolayers obtained from laser thinning, with those acquired from multilayers containing more defect-bound excitons, whereas those lasered from bilayers presenting a trion-dominated profile similar to as-grown monolayers. …”
Get full text

Roughness-Controlled Self-Assembly of Mannitol/LB Agar Microparticles by Polymorphic Transformation for Pulmonary Drug Delivery by Zhang, Fengying, Ngoc, Nguyen Thi Quynh, Tay, Bao Hui, Mendyk, Aleksander, Shao, Yu-Hsuan, Lau, Raymond

“…Comparison of ACI results and image analysis of SEM images shows that an increase in the particle surface roughness can increase the fine particle fractions (FPFs) using the rod-covered mannitol microparticles as drug carriers. …”
Get full text
Get full text

Understanding Dengue Virus Capsid Protein Interaction with Key Biological Targets by Faustino, André F., Martins, Ivo C., Carvalho, Filomena A., Castanho, Miguel A. R. B., Maurer-Stroh, Sebastian, Santos, Nuno C.

“…APOE N-terminal and PLIN3 C-terminal regions are remarkably similar, namely APOE α-helix 4 (APOEα4) and PLIN3 α-helix 5 (PLIN3α5) sequences, which are also highly superimposable structurally. …”
Get full text
Get full text

Visual hull based 3D reconstruction of shocks in under-expanded supersonic bevelled jets by Lim, Desmond Haoxiang, New, Tze How, Mariani, Raffaello, Cui, Y. D.

“…This is key to achieving accurate and high-resolution reconstructed shock waves for both axisymmetric and asymmetric test cases with an average of 2.5% error when validated against raw schlieren images. …”
Get full text
Get full text

Integrated optimization algorithm: a metaheuristic approach for complicated optimization by Li, Chen, Chen, Guo, Liang, Gaoqi, Luo, Fengji, Zhao, Junhua, Dong, Zhao Yang

“…IOA is synthesized from 5 sub-algorithms: follower search, leader search, wanderer search, crossover search, and role learning. …”
Get full text

Efficient visible light modulation based on electrically tunable all dielectric metasurfaces embedded in thin-layer nematic liquid crystals by Sun, Mingyu, Xu, Xuewu, Sun, Xiao Wei, Liang, Xin’an, Valuckas, Vytautas, Zheng, Yuanjin, Paniagua-Domínguez, Ramón, Kuznetsov, Arseniy I.

“…Small driving voltages from 3~5 V are sufficient to tune the metasurface resonances, with an associated transmission modulation of more than 65%. …”
Get full text
Get full text

Toward a neuroscientific understanding of play: a dimensional coding framework for analyzing infant–adult play patterns by Neale, Dave, Clackson, Kaili, Georgieva, Stanimira, Dedetas, Hatice, Scarpate, Melissa, Wass, Sam, Leong, Victoria

“…It is intended that this fine-grained coding of play behavior will be easily assimilated with, and inform, future analysis of neural data that is also collected during adult–infant play. …”
Get full text
Get full text

A novel gravity-driven nanofibrous membrane for point-of-use water disinfection: polydopamine-induced in situ silver incorporation by Wang, Jianqiang, Wu, Yichao, Yang, Zhe, Guo, Hao, Cao, Bin, Tang, Chuyang Y.

“…These nanoparticles were uniformly distributed on the surface of nanofibers with no apparent agglomeration at a silver loading up to 4.36 wt.% (cPAN-Ag1.5). The silver-incorporated membrane cPAN-Ag1.5 achieved a high pure water flux of 130 Lm−2 h−1 at 10-cm water head, demonstrating the feasibility of energy-efficient gravity-driven filtration and eliminating the need for electrical power. …”
Get full text
Get full text

The protocol of a clinical effectiveness trial comparing standard step-up care, early combination DMARD therapy and early use of TNF inhibitors for the treatment of moderate to sev... by Watson, M, Tillett, W, Jadon, D, Massa, MS, Francis, A, Gullick, N, Rombach, I, Sinomati, Y, Tucker, L, Coates, LC

“…Early use of biologics has also been shown to be superior to methotrexate but these drugs are costly and not usually funded first line. However, if a short course of biologics can rapidly suppress inflammation allowing treatment to be withdrawn and response maintained on methotrexate, this may be a cost-effective model for early use.…”

Tetratricopeptide repeat domain 9A modulates anxiety-like behavior in female mice by Lim, Lee Wei, Shrestha, Smeeta, Or, Yu Zuan, Tan, Shawn Zheng Kai, Chung, Hwa Hwa, Sun, Yang, Lim, Chew Leng, Khairuddin, Sharafuddin, Lufkin, Thomas, Lin, Valerie Chun Ling

“…Interestingly, the heightened anxiety in TTC9A−/− mice under EB influence is consistent with a greater induction of TPH 2, and 5-HTT by EB in DRN that play key roles in emotion regulation. …”
Get full text
Get full text

An analysis of contact stiffness and frictional receding contacts by Parel, KS

“…The tangential contact stiffness for ground Ti-6Al-4V surfaces is measured to linearly decrease with the application of tangential load, approaching zero at slip. …”

Performance of epoxy-based self-healing mortar by Ariffin, Nur Farhayu

Get full text

Current and future challenges of hybrid electrochemical-mechanical machining process for micro- and nano-manufacturing by Ahmad Shahir, Jamaludin, Mohd Nizar, Muhd Razali, Nurul Nadia, Nor Hamran, Mohd Zairulnizam, Mohd Zawawi, Mohd Amran, Md Ali

“…Through empirical, analytical, and numerical optimization methods, HEMM’s performance can be fine-tuned to meet specific requirements. Its applications span various fields, from microfluidics and micro-optics to aerospace and biomedical devices, underscoring its transformative potential in contemporary manufacturing. …”
Get full text
Get full text
Get full text

Experimental and AI-driven enhancements in gas-phase photocatalytic CO2 conversion over synthesized highly ordered anodic TiO2 nanotubes by Hossen, Md. Arif, Hasan, Md. Munirul, Ahmed, Yunus, Azrina, Abd Aziz, Nurashikin, Yaacof, Leong, Kah Hon

“…The K-fold cross-validation method was employed to fine-tune the hyperparameters of the ML models. Compared to other ML models, the artificial neural networks (ANN) model showed an outstanding rating of performance evaluation metrics, including R2, MSE, RMSE, and MRE. …”
Get full text

A multi-view context-aware approach to Android malware detection and malicious code localization by Narayanan, Annamalai, Chandramohan, Mahinthan, Chen, Lihui, Liu, Yang

“…Besides multi-view learning, MKLDroid’s unique and salient trait is its ability to locate fine-grained malice code portions in dependency graphs (e.g., methods/classes). …”
Get full text

Full-spectrum out-of-distribution detection by Yang, Jingkang, Zhou, Kaiyang, Liu, Ziwei

“…These new benchmarks have a more fine-grained categorization of distributions (i.elet@tokeneonedot, training ID, covariate-shifted ID, near-OOD, and far-OOD) for the purpose of more comprehensively evaluating the pros and cons of algorithms. …”
Get full text