A cross-scale framework for evaluating flexibility values of battery and fuel cell electric vehicles by Liu, Ruixue, He, Guannan, Wang, Xizhe, Mallapragada, Dharik, Zhao, Hongbo, Shao-Horn, Yang, Jiang, Benben

“…This article analyzed and compared the flexibility values of battery electric vehicles and fuel cell electric vehicles for planning and operating interdependent electricity and hydrogen supply chains while considering battery degradation costs. …”
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Characterization of progesterone receptor isoform-selective activities of progesterone receptor modulators in breast cancer cells. by Leo, Joyce Ching Li.

“…This study reveals the effects of progesterone receptor modulators (PRMs) mediated by PR isoforms in PR-transfected MDA-MB-231 cells. Through PR-A and PR-B, PRMs CP8668, AED and Dex-Mes exhibited progesterone agonist effect in which they induced cell spreading, focal adhesion, cell migration and inhibited cell cycle progression. …”
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Elucidating the size-dependency of in vitro digested polystyrene microplastics on human intestinal cells health and function by Ma, Yiyuan, Koh, Cheryl Jie Yan, Lim, Hong Kit, Shi, Pujiang, Tay, Chor Yong

“…Interestingly, it is found that the 0.1 µm PS-MPs can perturb redox homeostasis in NCM460 but not in Caco-2 cells. Based on the in vitro experimental boundaries and findings, it is concluded that ingested PS-MPs pose little acute cytotoxic harm to human gastrointestinal health.…”
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The effect of the amyloid-beta peptide on the fluidity of cell membranes : a study by fluorescence correlation spectroscopy by Ng, Justin Wei Qing

“…We therefore sought to find a conclusive answer to the question of whether Aβ affects cell plasma membrane fluidity. …”
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Cathodoluminescence of self-organized heterogeneous phases in multidimensional perovskite thin films by Cortecchia, Daniele, Lew, Kar Cheng, So, Jin-Kyu, Bruno, Annalisa, Soci, Cesare

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A novel method for segmenting growth of cells in sheared endothelial culture reveals the secretion of an anti-inflammatory mediator by Ghim, Mean, Pang, Kuin T., Arshad, Mehwish, Wang, Xiaomeng, Weinberg, Peter D.

“…In one paradigm, endothelial cells are cultured in devices that produce spatially varying shear stress profiles, and the local profile is compared with the properties of cells at the same position. …”
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Epithelial-mesenchymal transition of cancer cells using bioengineered hybrid scaffold composed of hydrogel/3D-fibrous framework by Pal, Mintu, Chen, Huizhi, Lee, Bae Hoon, Lee, Justin Yin Hao, Yip, Yun Sheng, Tan, Nguan Soon, Tan, Lay Poh

“…Our findings revealed that 3D hybrid scaffold enhances cell proliferation and induces cancer cells to undergo EMT, as demonstrated by significant up-regulation of EMT associated transcriptional factors including Snail1, Zeb1, and Twist2; and mesenchymal markers whereas epithelial marker, E-Cadherin was downregulated. …”
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A Model of Fuel Cell Based Electricity Generation in Malaysia: Life Cycle Approach (S/O 14199) by Mohd Shafie, Shafini, Othman, Zakirah, Hami, Norsiah, Omar, Salmah

“…Moving toward 2050, the fuel cell energy system is targeting to be one of potential green energy. …”
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In vitro and in silico studies of Lawsone on inflammation-induced skin cells for development of skin anti-inflammatory treatment by Abdullah, Shazleen Sofea, Mohammad Latif, Muhammad Alif, Md Tohid, Siti Farah

“…In silico works predicted lawsone’s ability to bind to TNF-α with good binding affinity without disruption to the protein’s structure stability.Lawsone is proven to be safe towards non-pathological cells. …”
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A faster chemical bath deposition method for SnO2 ETLs in perovskite solar cells by Wong, Zi Sheng

“…However, more studies are still required to find out the chemical reaction mechanisms and growth mechanisms to further improve yield.…”
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Cytotoxic effect of Bajong LN rice methanol extract on human squamous cell Carcinoma, ORL-48 by Vivi Noryati Ahmad, Nur Aliana Hidayah Mohamed, Zulkhairi Amom, Khor, Goot Heah, Nurhayati Mohamad Zain, Indah Mohd Amin

“…Morphological analysis and the Trypan blue exclusion assay corroborated the MTS assay's findings. Our preliminary findings provide the first scientific evidence of the cytotoxic effect of BLN-ME specifically against human squamous cell carcinoma, ORL-48 cells. …”
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High expression of MnSOD promotes survival of circulating breast cancer cells and increases their resistance to doxorubicin by Fu, Afu, Ma, Shijun, Wei, Na, Tan, Blanche Xiao Xuan, Tan, Ern Yu, Luo, Kathy Qian

“…Specific siRNA-mediated MnSOD knockdown reversed all three phenotypes. Our findings therefore suggest that MnSOD plays an important integrative role in supporting cancer cell survival in circulation, metastasis, and doxorubicin resistance. …”
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Phytochemical analysis and cytotoxic effects of mango (Mangifera indica L) kernel on breast cancer cell lines by Abdullah, Al-Shwyeh Hussah

“…It is suggested that the anticancer effect of the M.indica extract is via modulation of redox status through its antioxidant constituents and induction of apoptosis. These findings suggest that M. indica kernel extract, with antiproliferative properties towards cancer cells, while relatively innocuous to normal cells, is a good candidate as an alternative to or for supplementation for current chemotherapies in the treatment of breast cancers, without showing the side-effects associated with these anticancer drugs.…”
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Computational modeling of light processing in the habenula and dorsal raphe based on laser ablation of functionally-defined cells by Cheng, Ruey-Kuang, Jagannathan, N. Suhas, Kathrada, Ahmad Ismat, Jesuthasan, Suresh, Tucker-Kellogg, Lisa

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Thermal proteome profiling of breast cancer cells reveals proteasomal activation by CDK4/6 inhibitor palbociclib by Miettinen, Teemu P., Peltier, Julien, Härtlova, Anetta, Gierliński, Marek, Jansen, Valerie M., Trost, Matthias, Björklund, Mikael

“…In order to identify a molecular mechanism responsible for palbociclib‐induced senescence, we performed thermal proteome profiling of MCF7 breast cancer cells. In addition to affecting known CDK4/6 targets, palbociclib induces a thermal stabilization of the 20S proteasome, despite not directly binding to it. …”
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Contribution of zeolitic imidazolate framework-8 in improving the performance of polymer electrolyte membrane for direct methanol fuel cell by Junoh, Hazlina, Awang, Nuha, Ahmad, Siti Nur Afifi, Azhar, Masaud, Jaafar, Juhana, Md. Nordin, Nik Abdul Hadi, Ismail, Ahmad Fauzi, Qtaishat, Mohammed Rasool, Matsuura, Takeshi, Othman, Mohd. Hafiz Dzarfan, Abdul Rahman, Mukhlis, Mohd. Zainoodin, Azran

Ligand-specific factors influencing GLP-1 receptor post-endocytic trafficking and degradation in pancreatic beta cells by Fang, Zijian, Chen, Shiqian, Manchanda, Yusman, Bitsi, Stavroula, Pickford, Philip, David, Alessia, Shchepinova, Maria M., Corrêa, Ivan R., Jr., Hodson, David J., Broichhagen, Johannes, Tate, Edward W., Reimann, Frank, Salem, Victoria, Rutter, Guy A., Tan, Tricia, Bloom, Stephen R., Tomas, Alejandra, Jones, Ben

“…Experiments were performed in primary islet cells, INS-1 832/3 clonal beta cells and HEK293 cells, using biorthogonal labelling of GLP-1R to determine its localisation and degradation after treatment with GLP-1, exendin-4 and several further GLP-1R agonist peptides. …”
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Connecting genomic results for psychiatric disorders to human brain cell types and regions reveals convergence with functional connectivity by Yao, S, Harder, A, Darki, F, Chang, Y, Li, A, Nikouei, K, Volpe, G, Lundström, JN, Zeng, J, Wray, NR, Lu, Y, Sullivan, PF, Hjerling-Leffler, J

“…Using functional MRI connectivity, we further confirmed the significance of the central and lateral amygdala, hippocampal body, and prefrontal cortex in distinguishing schizophrenia cases from controls. Our findings underscore the value of single-cell transcriptomics in understanding the polygenicity of psychiatric disorders and suggest a promising alignment of genomic, transcriptomic, and brain imaging modalities for identifying common biological targets.…”

Interferon-α promotes HLA-B-restricted presentation of conventional and alternative antigens in human pancreatic β-cells by Carré, A, Samassa, F, Zhou, Z, Perez-Hernandez, J, Lekka, C, Manganaro, A, Oshima, M, Liao, H, Parker, R, Nicastri, A, Brandao, B, Colli, ML, Eizirik, DL, Aluri, J, Patel, D, Göransson, M, Burgos Morales, O, Anderson, A, Landry, L, Kobaisi, F, Scharfmann, R, Marselli, L, Marchetti, P, You, S, Ternette, N

“…Interferon (IFN)-α is the earliest cytokine signature observed in individuals at risk for type 1 diabetes (T1D), but the effect of IFN-α on the antigen repertoire of HLA Class I (HLA-I) in pancreatic β-cells is unknown. Here we characterize the HLA-I antigen presentation in resting and IFN-α-exposed β-cells and find that IFN-α increases HLA-I expression and expands peptide repertoire to those derived from alternative mRNA splicing, protein cis-splicing and post-translational modifications. …”

Functionalized sp2 carbon-conjugated covalent organic frameworks for interfacial modulation of inverted perovskite solar cells by Abuzeid, Hesham R., Tay, Darrell Jun Jie, Febriansyah, Benny, Kanwat, Anil, Salim, Teddy, Zhumekenov, Ayan A., Pullarkat, Sumod A., Mathews, Nripan

“…Interfacial modulation utilizing functional materials is proven to be crucial for obtaining high photovoltaic performance in lead halide perovskite solar cells (PSCs). This study investigates, for the first time, the utilization of a pyrene-based sp2 carbon-conjugated covalent organic framework (sp2c-COF) as an interfacial layer in inverted PSCs. …”
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